Cotton leaf curl Multan virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_000839845.1
Isolate India: Rajasthan, Sriganganagar
Release date 2015/2/12
Submitter Radhakrishnan,G., Malathi,V.G., Varma,A.
Host
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_003199
ACCGGATGGCCGCGCGATTTTTTTGGTGGGCCTTACCATTAACACTTGTCGGCCAATCATATGACTCCCTCAAAGCTAAATAACGCTCCCGCACACTATAAGTACTTGCGCACTAAGTTTCAAATTCAAACATGTGGGATCCACTATTAAACGAATTCCCTGATACGGTTCACGGGTTTCGGTGTATGCTTTCTGTGAAATATTTGCAACTTTTGTCGCAGGATTATTCACCGGATACGCTTGGGTACGAGTTAATACGGGATTTAATTTGTATTTTACGCTCCCGTAGTTATGTCGAAGCGAGCTGCCGATATCGTCATTTCTACGCCCGCGTCGAAAGTACGCCGGCGTCTGAACTTCGGCAGCCCATACACCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAACAACAGGCATGGACAAACAGGCCTATGAACAGGAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAGAGGATGTGAAGGTCCATGTAAGGTTCAGTCGTTTGAGTCCAGACATGATATTCAGCATATAGGTAAAGTAATGTGTGTTAGTGATGTTACTCGTGGTACTGGGCTGACCCATAGAGTTGGTAAGAGATTTTGTGTCAAGTCTGTTTATGTGTTGGGTAAGATATGGATGGATGAGAACATTAAGACGAAGAATCACACGAATAGTGTGATGTTTTTCTTGGTTAGAGATCGTAGACCTGTTGATAAACCTCAAGATTTTGGAGAGGTATTTAATATGTTTGATAATGAGCCCAGTACGGCGACTGTGAAGAATGTTCATCGTGATAGGTATCAAGTTCTGCGCAAATGGTATGCAACTGTCACCGGTGGACAATACGCTTCAAAGGAACAGGCTTTGGTCAAGAAGTTTGTCAGAGTTAACAATTATGTTGTTTACAATCAACAGGAAGCAGGAAAATACGAGAATCATACGGAAAATGCGTTAATGCTTTATATGGCTTGTACTCACGCTAGCAACCCTGTTTATGCTACGTTGAAGATTAGGATATATTTTTATGACTCTGTAACGAATTGATATTAATAAAGTTTAAATTTTATTTCTGAATATTGATCTACATACATAGTTTGTTGGATTACATTGTACAATACATGTTCTACAGCTTTAATAACTAAATTAATTGAAATTACACCGAGATTGTTCAGATATTTGAGGACTTGGTTTTTGAATACCCTTAAGAAAAGACCAGTCTGAGGCTGTAAGGTCGTCCAGATTCGGAAGGTTAGAAAACACTTGTGCAGTCCCAGAGCTTTCCGCGTGTTGTAGTTGAACTGGATCCTGATCGTGAGTATGTCCATATTCGTCGTGAATGGACGGTTGACGTGGCTGATGATCTTGAAATAAAGGGGATTTGGAACCTCCCAGATATATGCGCCATTCCCTGCTTGAGCTGCAGTGATGGGTTCCCCTGTGCGTGAATCCATGGTTGTGGCAGTTGATTGACAGATAATAAGAACACCCGCATTCAAGATCTACTCTCCTCCTCCTGTTGCGCCTCTTCGCTTCCCTGTGCTGTACTTTGATTGGTACCTGAGTACATGGGTCTATCAAGTGTGATGAAGATCGCATTCTTTAAAGCCCAATTTTTTAGTGCAGAATTCTTCTCTTCATCCAAAAACTCTTTATAGCTAGAATTGGGTCCTGGATTGCAGAGGAAGATGGTGGGAATTCCGCCTTTAATTTGAACTGGCTTCCCGTATTTTGTATTTGATTGCCAGTCCTTTTGGGCCCCCATGAACTCCTTAAAGTGCTTTAGGTAATGTGGGTTGACGTCATCAATGACGTTAAACCAGGCGTCATTACTGTATACCCTTGGGCTCAGATCTAGATGTCCACACAGATAATTATGTGGACCTAATGATCTGGCCCACATCGTCTTCCCCGTCCTACTGTCACCCTCAATCACTACACTTATTGGTCTATTGGCCCGCGCAGCGGCACTGACGACGTTCTCGGCAGCCCACACTTCAAGTTCTTCTGGAACTTGATCGAAAGAAGAAGAGGAAAAAGGAGAAACATAAGGAGCTGGTGGCTCCTGAAAGATTCTGTCTAGATTTGCATTTAAATTATGAAATTGCAGTACAAAATCCTTAGGAGCTAGTTCCTTAATGACTCTAAGAGCCTCCGACTTACTTCCCGCGTTAAGTGCTGCGGCGTAAGCGTCATTGGCTGTCTGTTGCCCTCCTCTTGCTGACCTTCCGTCGATCTGAAATTGCCCCCAGTCGAGAATGTCCCCGTCCTTCTCGGTGTAGGATTTGACGTCGGAGCTGGATTTAGCTCCCTGTATGTTCGGATGGAAATGTGCTGACCTGCTTGGGGAGACCAAGTCGAAGAATCGCATATTCTGGCACTTGAAATTCCCTTCGAACTGGATGAGAACATGCAAGTGAGGAGTCCCATCTTCGTGAAGCTCTCTGCAGATTCTAATATATTTTTTTGAAGTTGGGGTTTGTATATTTAATAATTGGGAAAGTGCTTCCTCTTTGGTGAGAGAACATTTGGGATAAGTGATGAAATAGTTTTTGGAATAAATACCGTTCCGCTTTGGAGGCATGTTGACTAAAATTGATCACCGATTGACCGCTCTTGCAACTCTCCCCGGTATATCGGTGATCAATATATAGTGATCACCAAATGGCATAATGGTAATAAAAAAACTTTAATTTGAAATTCAAACCAAAAGGCTAAAGCGGCCATCCGTTTAATATT

Gene Information

NCBI Accession NP_443740.1
Location 132-488
Gene Name AV2
Protein Name movement/pre-coat protein
Coding Region ATGTGGGATCCACTATTAAACGAATTCCCTGATACGGTTCACGGGTTTCGGTGTATGCTTTCTGTGAAATATTTGCAACTTTTGTCGCAGGATTATTCACCGGATACGCTTGGGTACGAGTTAATACGGGATTTAATTTGTATTTTACGCTCCCGTAGTTATGTCGAAGCGAGCTGCCGATATCGTCATTTCTACGCCCGCGTCGAAAGTACGCCGGCGTCTGAACTTCGGCAGCCCATACACCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAACAACAGGCATGGACAAACAGGCCTATGAACAGGAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAG
Protein Sequence MWDPLLNEFPDTVHGFRCMLSVKYLQLLSQDYSPDTLGYELIRDLICILRSRSYVEASCRYRHFYARVESTPASELRQPIHQPCCCPHCPRHKTTGMDKQAYEQEAQDVQDVQKSRCS

NCBI Accession NP_443741.1
Location 292-1062
Gene Name AV1
Protein Name coat protein
Coding Region ATGTCGAAGCGAGCTGCCGATATCGTCATTTCTACGCCCGCGTCGAAAGTACGCCGGCGTCTGAACTTCGGCAGCCCATACACCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAACAACAGGCATGGACAAACAGGCCTATGAACAGGAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAGAGGATGTGAAGGTCCATGTAAGGTTCAGTCGTTTGAGTCCAGACATGATATTCAGCATATAGGTAAAGTAATGTGTGTTAGTGATGTTACTCGTGGTACTGGGCTGACCCATAGAGTTGGTAAGAGATTTTGTGTCAAGTCTGTTTATGTGTTGGGTAAGATATGGATGGATGAGAACATTAAGACGAAGAATCACACGAATAGTGTGATGTTTTTCTTGGTTAGAGATCGTAGACCTGTTGATAAACCTCAAGATTTTGGAGAGGTATTTAATATGTTTGATAATGAGCCCAGTACGGCGACTGTGAAGAATGTTCATCGTGATAGGTATCAAGTTCTGCGCAAATGGTATGCAACTGTCACCGGTGGACAATACGCTTCAAAGGAACAGGCTTTGGTCAAGAAGTTTGTCAGAGTTAACAATTATGTTGTTTACAATCAACAGGAAGCAGGAAAATACGAGAATCATACGGAAAATGCGTTAATGCTTTATATGGCTTGTACTCACGCTAGCAACCCTGTTTATGCTACGTTGAAGATTAGGATATATTTTTATGACTCTGTAACGAATTGA
Protein Sequence MSKRAADIVISTPASKVRRRLNFGSPYTSRAAAPIVRVTKQQAWTNRPMNRKPRMYRMYRSPDVPRGCEGPCKVQSFESRHDIQHIGKVMCVSDVTRGTGLTHRVGKRFCVKSVYVLGKIWMDENIKTKNHTNSVMFFLVRDRRPVDKPQDFGEVFNMFDNEPSTATVKNVHRDRYQVLRKWYATVTGGQYASKEQALVKKFVRVNNYVVYNQQEAGKYENHTENALMLYMACTHASNPVYATLKIRIYFYDSVTN

NCBI Accession NP_443742.1
Location 1065-1469
Gene Name AC3
Protein Name replication enhancer protein
Coding Region ATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCAGGGAATGGCGCATATATCTGGGAGGTTCCAAATCCCCTTTATTTCAAGATCATCAGCCACGTCAACCGTCCATTCACGACGAATATGGACATACTCACGATCAGGATCCAGTTCAACTACAACACGCGGAAAGCTCTGGGACTGCACAAGTGTTTTCTAACCTTCCGAATCTGGACGACCTTACAGCCTCAGACTGGTCTTTTCTTAAGGGTATTCAAAAACCAAGTCCTCAAATATCTGAACAATCTCGGTGTAATTTCAATTAATTTAGTTATTAAAGCTGTAGAACATGTATTGTACAATGTAATCCAACAAACTATGTATGTAGATCAATATTCAGAAATAAAATTTAAACTTTATTAA
Protein Sequence MDSRTGEPITAAQAGNGAYIWEVPNPLYFKIISHVNRPFTTNMDILTIRIQFNYNTRKALGLHKCFLTFRIWTTLQPQTGLFLRVFKNQVLKYLNNLGVISINLVIKAVEHVLYNVIQQTMYVDQYSEIKFKLY

NCBI Accession NP_443743.1
Location 1162-1614
Gene Name AC2
Protein Name transcription activator protein
Coding Region ATGCGATCTTCATCACACTTGATAGACCCATGTACTCAGGTACCAATCAAAGTACAGCACAGGGAAGCGAAGAGGCGCAACAGGAGGAGGAGAGTAGATCTTGAATGCGGGTGTTCTTATTATCTGTCAATCAACTGCCACAACCATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCAGGGAATGGCGCATATATCTGGGAGGTTCCAAATCCCCTTTATTTCAAGATCATCAGCCACGTCAACCGTCCATTCACGACGAATATGGACATACTCACGATCAGGATCCAGTTCAACTACAACACGCGGAAAGCTCTGGGACTGCACAAGTGTTTTCTAACCTTCCGAATCTGGACGACCTTACAGCCTCAGACTGGTCTTTTCTTAAGGGTATTCAAAAACCAAGTCCTCAAATATCTGAACAATCTCGGTGTAATTTCAATTAA
Protein Sequence MRSSSHLIDPCTQVPIKVQHREAKRRNRRRRVDLECGCSYYLSINCHNHGFTHRGTHHCSSSREWRIYLGGSKSPLFQDHQPRQPSIHDEYGHTHDQDPVQLQHAESSGTAQVFSNLPNLDDLTASDWSFLKGIQKPSPQISEQSRCNFN

NCBI Accession NP_443744.1
Location 1511-2599
Gene Name AC1
Protein Name replication initiator protein
Coding Region ATGCCTCCAAAGCGGAACGGTATTTATTCCAAAAACTATTTCATCACTTATCCCAAATGTTCTCTCACCAAAGAGGAAGCACTTTCCCAATTATTAAATATACAAACCCCAACTTCAAAAAAATATATTAGAATCTGCAGAGAGCTTCACGAAGATGGGACTCCTCACTTGCATGTTCTCATCCAGTTCGAAGGGAATTTCAAGTGCCAGAATATGCGATTCTTCGACTTGGTCTCCCCAAGCAGGTCAGCACATTTCCATCCGAACATACAGGGAGCTAAATCCAGCTCCGACGTCAAATCCTACACCGAGAAGGACGGGGACATTCTCGACTGGGGGCAATTTCAGATCGACGGAAGGTCAGCAAGAGGAGGGCAACAGACAGCCAATGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCGGAGGCTCTTAGAGTCATTAAGGAACTAGCTCCTAAGGATTTTGTACTGCAATTTCATAATTTAAATGCAAATCTAGACAGAATCTTTCAGGAGCCACCAGCTCCTTATGTTTCTCCTTTTTCCTCTTCTTCTTTCGATCAAGTTCCAGAAGAACTTGAAGTGTGGGCTGCCGAGAACGTCGTCAGTGCCGCTGCGCGGGCCAATAGACCAATAAGTGTAGTGATTGAGGGTGACAGTAGGACGGGGAAGACGATGTGGGCCAGATCATTAGGTCCACATAATTATCTGTGTGGACATCTAGATCTGAGCCCAAGGGTATACAGTAATGACGCCTGGTTTAACGTCATTGATGACGTCAACCCACATTACCTAAAGCACTTTAAGGAGTTCATGGGGGCCCAAAAGGACTGGCAATCAAATACAAAATACGGGAAGCCAGTTCAAATTAAAGGCGGAATTCCCACCATCTTCCTCTGCAATCCAGGACCCAATTCTAGCTATAAAGAGTTTTTGGATGAAGAGAAGAATTCTGCACTAAAAAATTGGGCTTTAAAGAATGCGATCTTCATCACACTTGATAGACCCATGTACTCAGGTACCAATCAAAGTACAGCACAGGGAAGCGAAGAGGCGCAACAGGAGGAGGAGAGTAGATCTTGA
Protein Sequence MPPKRNGIYSKNYFITYPKCSLTKEEALSQLLNIQTPTSKKYIRICRELHEDGTPHLHVLIQFEGNFKCQNMRFFDLVSPSRSAHFHPNIQGAKSSSDVKSYTEKDGDILDWGQFQIDGRSARGGQQTANDAYAAALNAGSKSEALRVIKELAPKDFVLQFHNLNANLDRIFQEPPAPYVSPFSSSSFDQVPEELEVWAAENVVSAAARANRPISVVIEGDSRTGKTMWARSLGPHNYLCGHLDLSPRVYSNDAWFNVIDDVNPHYLKHFKEFMGAQKDWQSNTKYGKPVQIKGGIPTIFLCNPGPNSSYKEFLDEEKNSALKNWALKNAIFITLDRPMYSGTNQSTAQGSEEAQQEEESRS

NCBI Accession NP_443745.1
Location 2143-2445
Gene Name AC4
Protein Name AC4
Coding Region ATGGGACTCCTCACTTGCATGTTCTCATCCAGTTCGAAGGGAATTTCAAGTGCCAGAATATGCGATTCTTCGACTTGGTCTCCCCAAGCAGGTCAGCACATTTCCATCCGAACATACAGGGAGCTAAATCCAGCTCCGACGTCAAATCCTACACCGAGAAGGACGGGGACATTCTCGACTGGGGGCAATTTCAGATCGACGGAAGGTCAGCAAGAGGAGGGCAACAGACAGCCAATGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCGGAGGCTCTTAGAGTCATTAAGGAACTAG
Protein Sequence MGLLTCMFSSSSKGISSARICDSSTWSPQAGQHISIRTYRELNPAPTSNPTPRRTGTFSTGGNFRSTEGQQEEGNRQPMTLTPQHLTREVSRRLLESLRN

References More References in PubMed

1

LbCas12a mediated suppression of Cotton leaf curl Multan virus.

Ashraf S, et al.  Front Plant Sci. 2023 Aug 11;14:1233295. doi: 10.3389/fpls.2023.1233295. eCollection 2023.

PMID: 37636103
2

Prevalence, transmission and molecular characterization of Cotton leaf curl Multan virus infecting hollyhock plants in Pakistan.

Azeem H, et al.  Mol Biol Rep. 2022 Jun;49(6):5635-5644. doi: 10.1007/s11033-022-07557-0. Epub 2022 May 22.

PMID: 35598198
3

Cotton leaf curl Multan virus differentially regulates innate antiviral immunity of whitefly (Bemisia tabaci) vector to promote cryptic species-dependent virus acquisition.

Farooq T, et al.  Front Plant Sci. 2022 Nov 14;13:1040547. doi: 10.3389/fpls.2022.1040547. eCollection 2022.

PMID: 36452094
4

Cotton leaf curl Multan virus C4 protein suppresses autophagy to facilitate viral infection.

Yang M, et al.  Plant Physiol. 2023 Aug 31;193(1):708-720. doi: 10.1093/plphys/kiad235.

PMID: 37073495
5

Cotton leaf curl Multan betasatellite impaired ToLCNDV ability to maintain cotton leaf curl Multan alphasatellite.

Iqbal Z, et al.  Braz J Biol. 2022 Jul 25;84:e260922. doi: 10.1590/1519-6984.260922. eCollection 2022.

PMID: 35894353
6

Occurrence of Cotton leaf curl Multan virus and associated betasatellites with leaf curl disease of Bhut-Jolokia chillies (Capsicum chinense Jacq.) in India.

Yogindran S, et al.  Mol Biol Rep. 2021 Mar;48(3):2143-2152. doi: 10.1007/s11033-021-06223-1. Epub 2021 Feb 26.

PMID: 33635470
7

An Insight into Cotton Leaf Curl Multan Betasatellite, the Most Important Component of Cotton Leaf Curl Disease Complex.

Zubair M, et al.  Viruses. 2017 Sep 29;9(10):280. doi: 10.3390/v9100280.

PMID: 28961220
8

Dominance of recombinant cotton leaf curl Multan-Rajasthan virus associated with cotton leaf curl disease outbreak in northwest India.

Biswas KK, et al.  PLoS One. 2020 Apr 22;15(4):e0231886. doi: 10.1371/journal.pone.0231886. eCollection 2020.

PMID: 32320461
9

Transmission efficiency of Cotton leaf curl Multan virus by three cryptic species of Bemisia tabaci complex in cotton cultivars.

Chen T, et al.  PeerJ. 2019 Oct 1;7:e7788. doi: 10.7717/peerj.7788. eCollection 2019.

PMID: 31592168
10

Recombinant variants of cotton leaf curl Multan virus is associated with the breakdown of leaf curl resistance in cotton in northwestern India.

Chakrabarty PK, et al.  Virusdisease. 2020 Mar;31(1):45-55. doi: 10.1007/s13337-020-00568-0. Epub 2020 Feb 8.

PMID: 32206698