Cotton leaf curl Kokhran virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_000840425.1
Release date 2015/2/12
Submitter Zhou,X., Liu,Y., Robinson,D.J., Harrison,B.D.
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_004583
ACCGGATGGCCGCGCGATTTTTTTGTGGGCCCTACCATTAACTCTTGTCGGCCAATCATATGACGCGCTCAAAGCTTAAATAATTCTCCCGCTTATTATAAGTACTTCGTTGCTAAGTATGCGTTTGAAAAATGTGGGATCCACTGTTAAATGAGTTCCCCGACACCGTTCACGGTTTTAGGTGTATGTTAGCAGTTAAATATTTGCAGTTAGTAGAGAAAACTTACTCTCCTGATACATTGGGTTACGATTTGATAAGGGATTTAATCCTGGTAATAAGGGCTAGGAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAGAGGATGTGAAGGTCCATGTAAGGTTCAGTCGTTTGAGTCCAGACATGATATTCAGCATATAGGTAAAGTAATGTGTGTTAGTGATGTTACTCGTGGTACTGGGCTGACCCATAGAGTTGGTAAGAGATTTTGTGTTAAGTCTGTTTATGTGTTGGGTAAGATCTGGATGGATGAGAACATTAAGACGAAGAATCACACGAATAGTGTGATGTTTTTCTTGGTTAGAGATCGTAGACCTGTTGATAAACCTCAAGATTTTGGAGAGGTATTTAATATGTTTGATAATGAGCCCAGTACGGCGACTGTGAAGAATGTTCATCGTGATAGGTATCAAGTTCTGCGCAAATGGTATGCAACTGTCACCGGTGGACAATACGCTTCAAAGGAACAAGCTCTCGTGAAGAAATTTATTAGAGTTAATAATTATGTTGTGTATAACCAGCAGGAAGCTGGCAAGTATGAGAATCATTCTGAGAATGCTTTAATGTTGTATATGGCGTGTACTCACGCCTCTAACCCAGTGTATGCTACCTTGAAGATACGGATCTACTTCTATGATTCCGTGACAAATTAATAAATATTGAATTTTATTGAAGATGATTGGTCTACAAATACAACATGTTGTAATACATTCCATAATACATGATCAACTGCTCTAACTACATTATTAATACTGACAATTCCTAAGTTATTTAAATATTTAAGCACTTGAGTCCTAAAGACCCTTAAGAAACGACCAGTCGGAGGCTGTGAGGTCATCCAGATTCGGAAAGCTATGAAACATTTGTGTATCCCCAACGCTTTCCTCAGGTTGTGATTGAACTGTATCTGGACGGTGATGATGTCTCTGTTCATTAGGAATGCTCGATTGTGGTGCTCTGTTATCTTGAAATACAGGGGATTTTGAACCTCCCAGATAAACACGCCATTCTCTGCTTGAGCTGCAGTGATGAGTTCCCCTGTGCGTGAATCCATGGTTGTGGCAGGCTAATGCTATGAAGTACGAACACCCACAAGGGAGATCAACTCTCCGACGTCTGGTCCCCTTCTTGGCTAGCCTGTGCTGCACTTTGATTGGAACCTGAGTAGAGTGGGCTCTCGAGGGTGATGAAGATTGCATTCTTTAAAGCCCAATTTTTGAGTGCAGAATTCTTCTCTTCATCCAAAAACTCTTTATAGCTTGAATTGGGTCCTGGATTGCAGAGGAAGATAGTGGGAATTCCGCCTTTAATTTGAACTGGCTTCCCGTATTTTGTATTTGATTGCCAGTCCTTTTGGGCCCCCATGAACTCCTTAAAGTGCTTTAGGTAATGCGGGTCGACGTCATCAATGACGTTAAACCAGGCGTCATTACTGTATACCCTTGGGCTCAGATCTAGATGTCCACACAGATAATTATGTGGACCTAATGATCTGGCCCACATCGTCTTCCCCGTCCTACTGTCACCCTCAATCACTACACTTATTGGTCTATTGGCCCGCGCAGCGGCACTGACGACGTTCTCGGCAGCCCATACTTCAAGTTCTTCTGGAACTTGATCGAAAGAAGAAGAGGAAAAAGGAGAAACATAAGGAGCTGGTGGCTCCTGAAAGATTCTGTCTAGATTTGCATTTAAATTATGAAATTGCAGCACAAAATCCTTAGGAGCTAGTTCCTTAATGACTCTAAGAGCCTCCGACTTACTTCCCGCGTTAAGTGCTGCGGCGTAAGCGTCATTGGCTGTCTGTTGCCCTCCTCTTGCTGACCTTCCGTCGATCTGAAATTGCCCCCAGTCGAGAATGTCCCCGTCCTTCTCGATGTAGGATTTGACGTCGGAGCTGGATTTAGCTCCCTGTATGTTCGGATGGAAATGTGCTGACCTGCTTGGGGAGACCAAGTCGAAGAATCGCATATTCTGGCACTTGAATTTCCCTTCGAACTGGATGAGAACATGCAAGTGAGGAGTCCCATCTTCGTGAAGCTCTCTGCAGATTCTAATATATTTTTTTGAAGTTGGGGTTTGTATATTTAATAATTGGGAAAGTGCTTCCTCTTTGGTGAGAGAACATTTGGGATAAGTGATGAAATAGTTTTTGGAATAAATACCGTTCCGCTTTGGAGGCATGTTGACTAAAATTGATCACCGATTGACCGCTCTTGCAACTCTCCCCGGTATATCGGTGATCAATATATAGTGATCACCAAATGGCATAATGGTAATAAAAAAACTTTAATTTGAAATTCAAACCAAAAGGCTAAAGCGGCCATCCGTTTAATATT

Gene Information

NCBI Accession NP_795346.1
Location 132-488
Gene Name AV2
Protein Name AV2 protein
Coding Region ATGTGGGATCCACTGTTAAATGAGTTCCCCGACACCGTTCACGGTTTTAGGTGTATGTTAGCAGTTAAATATTTGCAGTTAGTAGAGAAAACTTACTCTCCTGATACATTGGGTTACGATTTGATAAGGGATTTAATCCTGGTAATAAGGGCTAGGAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAG
Protein Sequence MWDPLLNEFPDTVHGFRCMLAVKYLQLVEKTYSPDTLGYDLIRDLILVIRARNYVEATSRYNHFHARFEGTPPSQLRQPICEPCCCPHCPRHQSKSMGEQAHEQKAQDVQDVQKSRCS

NCBI Accession NP_795347.1
Location 292-1062
Gene Name AV1
Protein Name coat protein
Coding Region ATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGTCCAGATGTTCCTAGAGGATGTGAAGGTCCATGTAAGGTTCAGTCGTTTGAGTCCAGACATGATATTCAGCATATAGGTAAAGTAATGTGTGTTAGTGATGTTACTCGTGGTACTGGGCTGACCCATAGAGTTGGTAAGAGATTTTGTGTTAAGTCTGTTTATGTGTTGGGTAAGATCTGGATGGATGAGAACATTAAGACGAAGAATCACACGAATAGTGTGATGTTTTTCTTGGTTAGAGATCGTAGACCTGTTGATAAACCTCAAGATTTTGGAGAGGTATTTAATATGTTTGATAATGAGCCCAGTACGGCGACTGTGAAGAATGTTCATCGTGATAGGTATCAAGTTCTGCGCAAATGGTATGCAACTGTCACCGGTGGACAATACGCTTCAAAGGAACAAGCTCTCGTGAAGAAATTTATTAGAGTTAATAATTATGTTGTGTATAACCAGCAGGAAGCTGGCAAGTATGAGAATCATTCTGAGAATGCTTTAATGTTGTATATGGCGTGTACTCACGCCTCTAACCCAGTGTATGCTACCTTGAAGATACGGATCTACTTCTATGATTCCGTGACAAATTAA
Protein Sequence MSKRPADIIISTPASKVRRRLNFDSPYVSRAAAPIVRVTKAKAWANRPMNRKPRMYRMYRSPDVPRGCEGPCKVQSFESRHDIQHIGKVMCVSDVTRGTGLTHRVGKRFCVKSVYVLGKIWMDENIKTKNHTNSVMFFLVRDRRPVDKPQDFGEVFNMFDNEPSTATVKNVHRDRYQVLRKWYATVTGGQYASKEQALVKKFIRVNNYVVYNQQEAGKYENHSENALMLYMACTHASNPVYATLKIRIYFYDSVTN

NCBI Accession NP_795348.1
Location 1059-1463
Gene Name AC3
Protein Name AC3 protein
Coding Region ATGGATTCACGCACAGGGGAACTCATCACTGCAGCTCAAGCAGAGAATGGCGTGTTTATCTGGGAGGTTCAAAATCCCCTGTATTTCAAGATAACAGAGCACCACAATCGAGCATTCCTAATGAACAGAGACATCATCACCGTCCAGATACAGTTCAATCACAACCTGAGGAAAGCGTTGGGGATACACAAATGTTTCATAGCTTTCCGAATCTGGATGACCTCACAGCCTCCGACTGGTCGTTTCTTAAGGGTCTTTAGGACTCAAGTGCTTAAATATTTAAATAACTTAGGAATTGTCAGTATTAATAATGTAGTTAGAGCAGTTGATCATGTATTATGGAATGTATTACAACATGTTGTATTTGTAGACCAATCATCTTCAATAAAATTCAATATTTATTAA
Protein Sequence MDSRTGELITAAQAENGVFIWEVQNPLYFKITEHHNRAFLMNRDIITVQIQFNHNLRKALGIHKCFIAFRIWMTSQPPTGRFLRVFRTQVLKYLNNLGIVSINNVVRAVDHVLWNVLQHVVFVDQSSSIKFNIY

NCBI Accession NP_795349.1
Location 1204-1608
Gene Name AC2
Protein Name AC2 protein
Coding Region ATGCAATCTTCATCACCCTCGAGAGCCCACTCTACTCAGGTTCCAATCAAAGTGCAGCACAGGCTAGCCAAGAAGGGGACCAGACGTCGGAGAGTTGATCTCCCTTGTGGGTGTTCGTACTTCATAGCATTAGCCTGCCACAACCATGGATTCACGCACAGGGGAACTCATCACTGCAGCTCAAGCAGAGAATGGCGTGTTTATCTGGGAGGTTCAAAATCCCCTGTATTTCAAGATAACAGAGCACCACAATCGAGCATTCCTAATGAACAGAGACATCATCACCGTCCAGATACAGTTCAATCACAACCTGAGGAAAGCGTTGGGGATACACAAATGTTTCATAGCTTTCCGAATCTGGATGACCTCACAGCCTCCGACTGGTCGTTTCTTAAGGGTCTTTAG
Protein Sequence MQSSSPSRAHSTQVPIKVQHRLAKKGTRRRRVDLPCGCSYFIALACHNHGFTHRGTHHCSSSREWRVYLGGSKSPVFQDNRAPQSSIPNEQRHHHRPDTVQSQPEESVGDTQMFHSFPNLDDLTASDWSFLKGL

NCBI Accession NP_795350.1
Location 1511-2593
Gene Name AC1
Protein Name Rep
Coding Region ATGCCTCCAAAGCGGAACGGTATTTATTCCAAAAACTATTTCATCACTTATCCCAAATGTTCTCTCACCAAAGAGGAAGCACTTTCCCAATTATTAAATATACAAACCCCAACTTCAAAAAAATATATTAGAATCTGCAGAGAGCTTCACGAAGATGGGACTCCTCACTTGCATGTTCTCATCCAGTTCGAAGGGAAATTCAAGTGCCAGAATATGCGATTCTTCGACTTGGTCTCCCCAAGCAGGTCAGCACATTTCCATCCGAACATACAGGGAGCTAAATCCAGCTCCGACGTCAAATCCTACATCGAGAAGGACGGGGACATTCTCGACTGGGGGCAATTTCAGATCGACGGAAGGTCAGCAAGAGGAGGGCAACAGACAGCCAATGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCGGAGGCTCTTAGAGTCATTAAGGAACTAGCTCCTAAGGATTTTGTGCTGCAATTTCATAATTTAAATGCAAATCTAGACAGAATCTTTCAGGAGCCACCAGCTCCTTATGTTTCTCCTTTTTCCTCTTCTTCTTTCGATCAAGTTCCAGAAGAACTTGAAGTATGGGCTGCCGAGAACGTCGTCAGTGCCGCTGCGCGGGCCAATAGACCAATAAGTGTAGTGATTGAGGGTGACAGTAGGACGGGGAAGACGATGTGGGCCAGATCATTAGGTCCACATAATTATCTGTGTGGACATCTAGATCTGAGCCCAAGGGTATACAGTAATGACGCCTGGTTTAACGTCATTGATGACGTCGACCCGCATTACCTAAAGCACTTTAAGGAGTTCATGGGGGCCCAAAAGGACTGGCAATCAAATACAAAATACGGGAAGCCAGTTCAAATTAAAGGCGGAATTCCCACTATCTTCCTCTGCAATCCAGGACCCAATTCAAGCTATAAAGAGTTTTTGGATGAAGAGAAGAATTCTGCACTCAAAAATTGGGCTTTAAAGAATGCAATCTTCATCACCCTCGAGAGCCCACTCTACTCAGGTTCCAATCAAAGTGCAGCACAGGCTAGCCAAGAAGGGGACCAGACGTCGGAGAGTTGA
Protein Sequence MPPKRNGIYSKNYFITYPKCSLTKEEALSQLLNIQTPTSKKYIRICRELHEDGTPHLHVLIQFEGKFKCQNMRFFDLVSPSRSAHFHPNIQGAKSSSDVKSYIEKDGDILDWGQFQIDGRSARGGQQTANDAYAAALNAGSKSEALRVIKELAPKDFVLQFHNLNANLDRIFQEPPAPYVSPFSSSSFDQVPEELEVWAAENVVSAAARANRPISVVIEGDSRTGKTMWARSLGPHNYLCGHLDLSPRVYSNDAWFNVIDDVDPHYLKHFKEFMGAQKDWQSNTKYGKPVQIKGGIPTIFLCNPGPNSSYKEFLDEEKNSALKNWALKNAIFITLESPLYSGSNQSAAQASQEGDQTSES

NCBI Accession NP_795351.1
Location 2137-2439
Gene Name AC4
Protein Name AC4 protein
Coding Region ATGGGACTCCTCACTTGCATGTTCTCATCCAGTTCGAAGGGAAATTCAAGTGCCAGAATATGCGATTCTTCGACTTGGTCTCCCCAAGCAGGTCAGCACATTTCCATCCGAACATACAGGGAGCTAAATCCAGCTCCGACGTCAAATCCTACATCGAGAAGGACGGGGACATTCTCGACTGGGGGCAATTTCAGATCGACGGAAGGTCAGCAAGAGGAGGGCAACAGACAGCCAATGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCGGAGGCTCTTAGAGTCATTAAGGAACTAG
Protein Sequence MGLLTCMFSSSSKGNSSARICDSSTWSPQAGQHISIRTYRELNPAPTSNPTSRRTGTFSTGGNFRSTEGQQEEGNRQPMTLTPQHLTREVSRRLLESLRN

References More References in PubMed

1

In silico evaluation of molecular virus-virus interactions taking place between Cotton leaf curl Kokhran virus- Burewala strain and Tomato leaf curl New Delhi virus.

Ali NF, et al.  PeerJ. 2021 Oct 19;9:e12018. doi: 10.7717/peerj.12018. eCollection 2021.

PMID: 34721952
2

Cotton leaf curl Burewala virus with intact or mutant transcriptional activator proteins: complexity of cotton leaf curl disease.

Kumar J, et al.  Arch Virol. 2015 May;160(5):1219-28. doi: 10.1007/s00705-015-2384-4. Epub 2015 Mar 14.

PMID: 25772572
3

Engineered Disease Resistance in Cotton Using RNA-Interference to Knock down Cotton leaf curl Kokhran virus-Burewala and Cotton leaf curl Multan betasatellite Expression.

Ahmad A, et al.  Viruses. 2017 Sep 14;9(9):257. doi: 10.3390/v9090257.

PMID: 28906473
4

The antisense 5' end of the V2 gene confers enhanced resistance against the monopartite begomovirus cotton leaf curl Kokhran virus-Burewala strain.

Ali I, et al.  Acta Virol. 2019;63(1):26-35. doi: 10.4149/av_2019_101.

PMID: 30879310
5

Dominance of recombinant cotton leaf curl Multan-Rajasthan virus associated with cotton leaf curl disease outbreak in northwest India.

Biswas KK, et al.  PLoS One. 2020 Apr 22;15(4):e0231886. doi: 10.1371/journal.pone.0231886. eCollection 2020.

PMID: 32320461
6

Effects of the mutation of selected genes of cotton leaf curl Kokhran virus on infectivity, symptoms and the maintenance of cotton leaf curl Multan betasatellite.

Iqbal Z, et al.  Virus Res. 2012 Oct;169(1):107-16. doi: 10.1016/j.virusres.2012.07.016. Epub 2012 Jul 31.

PMID: 22871297
7

A Yellow Mosaic Disease of Soybean in Northern India is Caused by Cotton leaf curl Kokhran virus.

Raj SK, et al.  Plant Dis. 2006 Jul;90(7):975. doi: 10.1094/PD-90-0975C.

PMID: 30781056
8

Functional Analysis of Cotton Leaf Curl Kokhran Virus/Cotton Leaf Curl Multan Betasatellite RNA Silencing Suppressors.

Saeed M, et al.  Biology (Basel). 2015 Oct 23;4(4):697-714. doi: 10.3390/biology4040697.

PMID: 26512705
9

Sentinel plot surveillance of cotton leaf curl disease in Pakistan- a case study at the cultivated cotton-wild host plant interface.

Iqbal MJ, et al.  Virus Res. 2023 Aug;333:199144. doi: 10.1016/j.virusres.2023.199144. Epub 2023 Jun 7.

PMID: 37271420
10

Dominance of Cotton leaf curl Multan virus-Rajasthan strain associated with third epidemic of cotton leaf curl disease in Pakistan.

Mahmood MA, et al.  Sci Rep. 2024 Jun 12;14(1):13532. doi: 10.1038/s41598-024-63211-8.

PMID: 38866855