Tomato geminivirus 1

Basic Information

Genus Topilevirus
Isolate Brazil
Host
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

MF072688
ACGGATGTGGCCCCAGTTGCGAGCGCTTTAGCGCGAGCCTTTAATAAAGTGATAAAGTGAAACGCTACTTTTGACGTGGCACAATGTGAGCCGTAAAACGTGCAGAAAAAAAATAAAAAAAGCCGACAAGCAAATAACGTGGGCCCCACTAAATAAAGACATCGGAAAAAGGTAACATACTATATTATTCTTGCCTTCGTCCCTAAGTTTTGACTGGTCAAAACTTGCGGCGTACTCTATACGCTTCTTATTTGGTATATAAAGTGGTGTATTTTATACGCATTATGGAGTGGTCTTTTAACGCAGTGGTGTACATTATTGTGTACATTTGTACGCTATTCGTTACGCTCGTTAATGGATATTCCGTTATACGAAGTGAACGACTATCCCGGCGTCTACAATCAATTTCTACAGACTTGCGCCAATCGTCTAATTTCTTGGCAATTATCGAAGGTTCAATTGGAGCTCGACGTGAAAGGAATTTCAATCGACCGGAAGGAGCAGCTTCTGAAACTCCAGTAGTTCCTCGAGGAGTTCAAGAAGTTTAATCGGGTTATATCTTATCAACGCAATCATCTAGTGAAGTGTTGTTTGTATTCTACTTTCATTGCCAAATTTAGGTATGGCGGAGCGGAAGAGGAAGATGGAATGGTCGAAAGCGAATCGGAAGAGGAGTCGTACGACTCTGCCGAGGAATTCTAGGGTGTATGCTAGAAAACGACCTATATTGCGAGGTCCTAAATTGACTAGCAGGGATAAGGTTTATACGTATACGAAATACGAGACACTTACTACAGCGGGTGCGGTTTATCATCTCAATAGTTTTAGTCAGGGTTTAGCTAATAATCAACGTGCGACTTCCGTTGATATTGTTCATAATGTTCAGCTTAGGTTTTCTGTTGAGTTACCTACTGGTGCTATGGTTTTTTGTCGTCGTTACAAGATGTCATGGGCTGTTGTTCAAGATATGATGCCGGGAGATAGTATGCCAGCGGTCAGCGATATTTTTAGTATGACTTCTCCTCCTATTGAAGGTTTGGAGTATATTGCTGATGATAATCATCGCAGATTTCAAGTTAAAAAATTTGGAATTTTGTACTTGGAATCTGGTGGTGCTGACTACTCTGTTAATACTGGAAAGCAGACGTACAACGTACAAGATGCTTTGAAAAGGGTCTTCGTGAAGTGCAATACACGCGGTGTGTATGATAGTAACAGCTCTGCTGGTTCTATCAGTGCTATGAATTCTGGGGCTTTGTATTTTGTTGTAAATCCCACTTTCGCTGGGTATTTGGGTTTCAACATTACTGTGTATCATAATTCACCTGTTTAATACAGGTTTTTATTAATAAAGAAGTATTCTACATTTTGTTGTGACCATTCATAGATATCGCTATTCTGTATAGCTGTTTCGTATGATTGATCAGAATTACATAGGATAATAGATGGTATTCCTCCCTTTATTCTACATTTTTTCTTATATTTTTCGTTTACTGTGAAATCCTTTTGTGCTCCTAGGATTTCTTTTTTACATGGTAAAAACTGGAAAGGAATATCATCGAATACATTATATAACGCCGTGTTGTCATAGTTTGACCAGTCGACTCCTCCGCAGTAGTAATTATGTTTTCCCAAGCTTCTTGCCCATGCTGTTTTTCCACATCTCGTTGGACCTTCAATTATTGCGGTGGTGGGTCGGTCTGGTACCAGTTCTGGTTCCTATAAACAAAATATGAAGGTGACTCAGCTTGGTTTTCCCATGCTTCACGAATTTCCATTTTCGTTGTTTCTGATGCCCAGACCAAGTCTGAAAAATCAGCAGTAGGATTGATGTGAAGATAGGTATCGAAGCTTACGCAGTAGAGGTTTTGATCTGCCCAGTGTTGTAAGGACTCTGGAATGCCAATAAAATTTGTCCATCTGGGTTGATAACTCTCAGGGGGTGTGGGCCATTGTTTATCAGCCATGTATTCGAGGTTTCTATAGTTGTTGGCATACGTGTAGGGCTGTTCGGCCAGTACTCTGGTGAGGAAGTCAGACTTGGATGTGGATTCTGAGAGAATTCTTGTCCAGATAGCGTCTCTATTCTTCTTCGGACTTCTTCGGGAAGCTCTAAGAATACCTCTCTCCTCAAAGGTACCCCCCTTGGAAATGTAGTCCGCAACATCTGCATCCCTTCTTGGGATCTGGATGTTTGGATGATAAATTCCCGATCCGTTAGGGTCGGTGATGTCGAAGAACCTCTGGTTCTGCGTCTGAAACCTCTTCTCAGTCTGTACCAGACAGTGGATGTGTGGCTCTCCATCTTGATGGTTTTCCGTACAAGCTCTAACGTATGTGACGTTATAATCTTTTAGTAATTGAAAAAAGTAATCGATAATGAAAATTGGAATTAGAGGACACTTTGGATAGGTTAGAAAAAAGGATTTGCCCTGGATTTTAAAGGAAGAGGGTTGGCGAGGCATAGCTGCTGGCGCTACAGTGCTTTCTATTGTTTATTGTATTACAAGGATGGTGATCAGTTGATCAGTTATATACTAAATTAAATGGGCCGAATAGTGTTGGGCCGATTTATTGGGCTTCGTCAACTGGGGCACATCCTTTTAATATT

Gene Information

NCBI Accession ASU08499.1
Location 285-548
Protein Name hypothetical protein
Coding Region ATGGAGTGGTCTTTTAACGCAGTGGTGTACATTATTGTGTACATTTGTACGCTATTCGTTACGCTCGTTAATGGATATTCCGTTATACGAAGTGAACGACTATCCCGGCGTCTACAATCAATTTCTACAGACTTGCGCCAATCGTCTAATTTCTTGGCAATTATCGAAGGTTCAATTGGAGCTCGACGTGAAAGGAATTTCAATCGACCGGAAGGAGCAGCTTCTGAAACTCCAGTAGTTCCTCGAGGAGTTCAAGAAGTTTAA
Protein Sequence MEWSFNAVVYIIVYICTLFVTLVNGYSVIRSERLSRRLQSISTDLRQSSNFLAIIEGSIGARRERNFNRPEGAASETPVVPRGVQEV

NCBI Accession ASU08500.1
Location 355-522
Protein Name hypothetical protein
Coding Region ATGGATATTCCGTTATACGAAGTGAACGACTATCCCGGCGTCTACAATCAATTTCTACAGACTTGCGCCAATCGTCTAATTTCTTGGCAATTATCGAAGGTTCAATTGGAGCTCGACGTGAAAGGAATTTCAATCGACCGGAAGGAGCAGCTTCTGAAACTCCAGTAG
Protein Sequence MDIPLYEVNDYPGVYNQFLQTCANRLISWQLSKVQLELDVKGISIDRKEQLLKLQ

NCBI Accession ASU08496.1
Location 623-1333
Protein Name capsid protein
Coding Region ATGGCGGAGCGGAAGAGGAAGATGGAATGGTCGAAAGCGAATCGGAAGAGGAGTCGTACGACTCTGCCGAGGAATTCTAGGGTGTATGCTAGAAAACGACCTATATTGCGAGGTCCTAAATTGACTAGCAGGGATAAGGTTTATACGTATACGAAATACGAGACACTTACTACAGCGGGTGCGGTTTATCATCTCAATAGTTTTAGTCAGGGTTTAGCTAATAATCAACGTGCGACTTCCGTTGATATTGTTCATAATGTTCAGCTTAGGTTTTCTGTTGAGTTACCTACTGGTGCTATGGTTTTTTGTCGTCGTTACAAGATGTCATGGGCTGTTGTTCAAGATATGATGCCGGGAGATAGTATGCCAGCGGTCAGCGATATTTTTAGTATGACTTCTCCTCCTATTGAAGGTTTGGAGTATATTGCTGATGATAATCATCGCAGATTTCAAGTTAAAAAATTTGGAATTTTGTACTTGGAATCTGGTGGTGCTGACTACTCTGTTAATACTGGAAAGCAGACGTACAACGTACAAGATGCTTTGAAAAGGGTCTTCGTGAAGTGCAATACACGCGGTGTGTATGATAGTAACAGCTCTGCTGGTTCTATCAGTGCTATGAATTCTGGGGCTTTGTATTTTGTTGTAAATCCCACTTTCGCTGGGTATTTGGGTTTCAACATTACTGTGTATCATAATTCACCTGTTTAA
Protein Sequence MAERKRKMEWSKANRKRSRTTLPRNSRVYARKRPILRGPKLTSRDKVYTYTKYETLTTAGAVYHLNSFSQGLANNQRATSVDIVHNVQLRFSVELPTGAMVFCRRYKMSWAVVQDMMPGDSMPAVSDIFSMTSPPIEGLEYIADDNHRRFQVKKFGILYLESGGADYSVNTGKQTYNVQDALKRVFVKCNTRGVYDSNSSAGSISAMNSGALYFVVNPTFAGYLGFNITVYHNSPV

NCBI Accession ASU08498.1
Location NA
Protein Name replication-associated protein
Coding Region ATGCCTCGCCAACCCTCTTCCTTTAAAATCCAGGGCAAATCCTTTTTTCTAACCTATCCAAAGTGTCCTCTAATTCCAATTTTCATTATCGATTACTTTTTTCAATTACTAAAAGATTATAACGTCACATACGTTAGAGCTTGTACGGAAAACCATCAAGATGGAGAGCCACACATCCACTGTCTGGTACAGACTGAGAAGAGGTTTCAGACGCAGAACCAGAGGTTCTTCGACATCACCGACCCTAACGGATCGGGAATTTATCATCCAAACATCCAGATCCCAAGAAGGGATGCAGATGTTGCGGACTACATTTCCAAGGGGGGTACCTTTGAGGAGAGAGGTATTCTTAGAGCTTCCCGAAGAAGTCCGAAGAAGAATAGAGACGCTATCTGGACAAGAATTCTCTCAGAATCCACATCCAAGTCTGACTTCCTCACCAGAGTACTGGCCGAACAGCCCTACACGTATGCCAACAACTATAGAAACCTCGAATACATGGCTGATAAACAATGGCCCACACCCCCTGAGAGTTATCAACCCAGATGGACAAATTTTATTGGCATTCCAGAGTCCTTACAACACTGGGCAGATCAAAACCTCTACTGCGAACCAGAACTGGTACCAGACCGACCCACCACCGCAATAATTGAAGGTCCAACGAGATGTGGAAAAACAGCATGGGCAAGAAGCTTGGGAAAACATAATTACTACTGCGGAGGAGTCGACTGGTCAAACTATGACAACACGGCGTTATATAATGTATTCGATGATATTCCTTTCCAGTTTTTACCATGTAAAAAAGAAATCCTAGGAGCACAAAAGGATTTCACAGTAAACGAAAAATATAAGAAAAAATGTAGAATAAAGGGAGGAATACCATCTATTATCCTATGTAATTCTGATCAATCATACGAAACAGCTATACAGAATAGCGATATCTATGAATGGTCACAACAAAATGTAGAATACTTCTTTATTAATAAAAACCTGTATTAA
Protein Sequence MPRQPSSFKIQGKSFFLTYPKCPLIPIFIIDYFFQLLKDYNVTYVRACTENHQDGEPHIHCLVQTEKRFQTQNQRFFDITDPNGSGIYHPNIQIPRRDADVADYISKGGTFEERGILRASRRSPKKNRDAIWTRILSESTSKSDFLTRVLAEQPYTYANNYRNLEYMADKQWPTPPESYQPRWTNFIGIPESLQHWADQNLYCEPELVPDRPTTAIIEGPTRCGKTAWARSLGKHNYYCGGVDWSNYDNTALYNVFDDIPFQFLPCKKEILGAQKDFTVNEKYKKKCRIKGGIPSIILCNSDQSYETAIQNSDIYEWSQQNVEYFFINKNLY

NCBI Accession ASU08497.1
Location 1680-2465
Protein Name RepA
Coding Region ATGCCTCGCCAACCCTCTTCCTTTAAAATCCAGGGCAAATCCTTTTTTCTAACCTATCCAAAGTGTCCTCTAATTCCAATTTTCATTATCGATTACTTTTTTCAATTACTAAAAGATTATAACGTCACATACGTTAGAGCTTGTACGGAAAACCATCAAGATGGAGAGCCACACATCCACTGTCTGGTACAGACTGAGAAGAGGTTTCAGACGCAGAACCAGAGGTTCTTCGACATCACCGACCCTAACGGATCGGGAATTTATCATCCAAACATCCAGATCCCAAGAAGGGATGCAGATGTTGCGGACTACATTTCCAAGGGGGGTACCTTTGAGGAGAGAGGTATTCTTAGAGCTTCCCGAAGAAGTCCGAAGAAGAATAGAGACGCTATCTGGACAAGAATTCTCTCAGAATCCACATCCAAGTCTGACTTCCTCACCAGAGTACTGGCCGAACAGCCCTACACGTATGCCAACAACTATAGAAACCTCGAATACATGGCTGATAAACAATGGCCCACACCCCCTGAGAGTTATCAACCCAGATGGACAAATTTTATTGGCATTCCAGAGTCCTTACAACACTGGGCAGATCAAAACCTCTACTGCGTAAGCTTCGATACCTATCTTCACATCAATCCTACTGCTGATTTTTCAGACTTGGTCTGGGCATCAGAAACAACGAAAATGGAAATTCGTGAAGCATGGGAAAACCAAGCTGAGTCACCTTCATATTTTGTTTATAGGAACCAGAACTGGTACCAGACCGACCCACCACCGCAATAA
Protein Sequence MPRQPSSFKIQGKSFFLTYPKCPLIPIFIIDYFFQLLKDYNVTYVRACTENHQDGEPHIHCLVQTEKRFQTQNQRFFDITDPNGSGIYHPNIQIPRRDADVADYISKGGTFEERGILRASRRSPKKNRDAIWTRILSESTSKSDFLTRVLAEQPYTYANNYRNLEYMADKQWPTPPESYQPRWTNFIGIPESLQHWADQNLYCVSFDTYLHINPTADFSDLVWASETTKMEIREAWENQAESPSYFVYRNQNWYQTDPPPQ

References More References in PubMed

1

Breakdown of Ty-1-Based Resistance to Tomato Yellow Leaf Curl Virus in Tomato Plants at High Temperatures.

Koeda S, et al.  Phytopathology. 2024 Jan;114(1):294-303. doi: 10.1094/PHYTO-04-23-0119-R. Epub 2024 Feb 12.

PMID: 37321561
2

Resistance gene Ty-1 restricts TYLCV infection in tomato by increasing RNA silencing.

Ma X, et al.  Virol J. 2024 Oct 16;21(1):256. doi: 10.1186/s12985-024-02508-6.

PMID: 39415211
3

Sucrose Nonfermenting 1-Related Protein Kinase 1 Phosphorylates a Geminivirus Rep Protein to Impair Viral Replication and Infection.

Shen W, et al.  Plant Physiol. 2018 Sep;178(1):372-389. doi: 10.1104/pp.18.00268. Epub 2018 Jul 13.

PMID: 30006378
4

A New Geminivirus Associated with a Leaf Curl Disease of Tomato in Tanzania.

Chiang BT, et al.  Plant Dis. 1997 Jan;81(1):111. doi: 10.1094/PDIS.1997.81.1.111B.

PMID: 30870927
5

Deciphering gene specific molecular characterization and partial gene sequence for combined resistance to tomato leaf curl virus (ToLCV) (Ty-1, Ty-2 and Ty-3), fusarium wilt (I-2) and root- knot nematode (Mi-1) in selected fresh market breeding line of tomato (Solanum lycopersicom L.).

Nithyanandam A, et al.  Mol Biol Rep. 2024 Dec 18;52(1):59. doi: 10.1007/s11033-024-10150-2.

PMID: 39692918
6

Cy-1, a major QTL for tomato leaf curl New Delhi virus resistance, harbors a gene encoding a DFDGD-Class RNA-dependent RNA polymerase in cucumber (Cucumis sativus).

Koeda S, et al.  BMC Plant Biol. 2024 Oct 2;24(1):879. doi: 10.1186/s12870-024-05591-7.

PMID: 39358692
7

Gene editing in tomatoes.

Van Eck J.  Emerg Top Life Sci. 2017 Nov 10;1(2):183-191. doi: 10.1042/ETLS20170056.

PMID: 33525759
8

Tomato golden mosaic virus leftward gene expression: autoregulation of geminivirus replication protein.

Sunter G, et al.  Virology. 1993 Jul;195(1):275-80. doi: 10.1006/viro.1993.1374.

PMID: 8317105
9

Tomato yellow leaf curl virus: a whitefly-transmitted geminivirus with a single genomic component.

Navot N, et al.  Virology. 1991 Nov;185(1):151-61. doi: 10.1016/0042-6822(91)90763-2.

PMID: 1926771
10

Tomato leaf curl Yunnan virus-encoded C4 induces cell division through enhancing stability of Cyclin D 1.1 via impairing NbSKeta -mediated phosphorylation in Nicotiana benthamiana.

Mei Y, et al.  PLoS Pathog. 2018 Jan 2;14(1):e1006789. doi: 10.1371/journal.ppat.1006789. eCollection 2018 Jan.

PMID: 29293689