Tomato apical leaf curl virus

Basic Information

Genus Topilevirus
NCBI Assembly GCF_002890115.1
Isolate Argentina
Release date 2018/1/18
Submitter Vaghi Medina,G., Teppa,E., Bornancini,V.A., Flores,C.R., Marino Buslje,C., Lopez Lambertini,P.M.
Host
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_036591
ACGGCTTTGCCCCTCACTCTCTGTCCCATATTATCTGCCACGTGGTTGGTCAGCCTTAACTTACGGAAAAGTTGTCGGGTAAAGTAAAAAGTAGCCGCATCTTTTGACTTATTTCAAAAGTGTATGGCCCCTATGTTTTGGCGGGAAACCTTTCCGTAACCTCTATTACTTGCTTCGCAAGTAATCTTATTATAAAAGTATAAAGAAATGAATAAAAAATTCAATGGACTGGACCTTTAACGCCTGGGTCTATCTATTTGTTTTTATAAGTACAGTTATAATTACTGTATTTAATGGAGTTACCAGTATACAGCTCCTCAGAATATCCGAAAAGTTACAACGCATTTCTGCAGACTTGCGCGGATCGATTAGTCACCTGGCAATTACAATTGGTGTGGCAGAAGGTCGAGTATTTCAACCGTCACAAGGCGGACGAGTTCTTCGAGTGGGAAGAACTGTATCAGTTCCTAATAGAGTTCAGGAAGACCGTCCGACGGGCGGGGAGACGCAAGTCTCACCATAAAAAAATAGAAATCTATAATCTCTTTTGGATCAAAAGAGATGGGAGCAAATCAGGCGTTAATAAGTTGGGGTGCGAAGAAAAAGCGAAGTACTCCAAACCGTTCGAGTTGGACTCGGAGAGTTCGTAGGCGTCTTTCTTATTACCCTAGGTATATACCTAGGGGTCCTAAAAAAAATACCCGTGATAAGGTGTATACCTTTACAAGTTATAAGGCCTTTAGCGATTTAGGTGGTGTATGGTTGTTAAATGGTTTTGCCCAAGGTTTGGGTAATAACCAAAGAAATGGAAGCGTTGAAATTATTCGCGCTTTAAATTTGCGTTTAGGTGTTGCTATAGCAGAAGGTGCCACAGCATTAAATTTTGCTAGGGACTGGAACTGTACATGGTATGTAATTGCAGACCAGAGTCCTGGCACAACTATTCCAGCATTTACAGACATTTTTACCACAGGTTCTGCTGCTGTTGATGGTCTGGAATATATTCCAGATGATATGCATCTTCGTTTTCAGATTAAGATGAAGGGTAAATTGAAGTTCATTACTTCTGGAGTTAGTTATTCTACAGCAGTTACTTCCAAAACTGGCTACAATAAGTGCCATGATATTGTTAGAAAATTTAAATCAAAGTTGAATGTAAGAACTGATTATGATAGTAACAGTTCTGGAGGTGCTATTACAGATATAAAAAAGGGTGCTTTGTATTTAGTTATTAATCCTGAATTCAGCTGTTATGCTGGTGTAAATTGCACTATTTATCATAGTGGTCCTTATTATAAATAAAATATTTTACTTTGTTCTTACGTATATCAATCGTCACCCTCACTTTCCCCCCCAAGAAAGTGTTCATACGGTTGAGTCCTGAGCCCTCACCTTCCCCCCCAAATAAGCACGCGTTCTTTGATTTGGTAGGGCTTTAGCCCTACCAAATCAAAAGAACAAGATGGATGAAAAAATTAGTGGTTTATCTTGGTAGCAATTCCCTAAAGGGTTCAGCAATAGCAGAGTTACATTCATACGGAACAGGGTATAGTATGATATTAAAATTCTAAAAAAGCGATCCATCAATGAACTCATAAAGGACATTAGACTGACACCAAACATACAAATCAGAACGACTAATAGCCTCCTTATAAGAGCTATCAGGATTACATAATACTATTGAAGGAATGCCTCCTTTTATTGTACATTTTTTCCTATACTTTTCATTAACCGTGAAATCTTTTTGTGCTCCAAGTATTTCCTTTTTGCACGGCAAGTATTGAAATGGTATGTCGTCGAAAACATTATATATAGCGTGGGGATTGTACTCAGTCCAGTTCACTCCTCCGCAGAAATAATTGTGTAGTCCGAAGCTTCTTGCCCATGCTGTTTTACCTGTTCTTGTTGGGCCTTCAACAATGAGTGTTAATGGCCTATCGGGCTTATTCTCCGGGTCCTGAATCATTATAAATGTGTGGTCTAATGTTAGTAAAGTTATCTGGGTTTTCAAGAATCTGTTCTATAGATTCTTGTGCCATACTATCGTAAAAATCTAAATCATTTTGTGTTAATTGTGGAACGTCTAACAAAATGAAATCTCTATGTACCACGCATATGTTCTGTTCTACCCAATTTTTAATGGGCTCGGGTACGCCATTGAATATTGAGAATTTGGGTGTAAAATTCGCACTTGGTTTTGGCCACTTTTTGTTGGCCATGTATTCGAGGTTTCGCAGTTGTGTTGCGTATGTATAAGGTTGTTCTCGTTGACATCTGCTGAGGAAGTCCTCGGCGTTAGTGGATTCCTCGATGATCTTTCCCCATATAGTATCCCGAGATTTCTTAGGACTGCGTCTTGAAGCTCTAAGTAATCCTCGTTCCTCATATACTCCTCCCTTAGCGATGTAGTCTGCAACGTCAGCGTCCCTTCTTGGAATCTGGGCGTTTGGATGGTATGTGCTCTCTCTATTAGGGTCTGAAATGTCGAAGAATCTTGGGTTTCTTGTACTGAACTTCTCCTCCAATTGGACGAGGCAGTGGAGATGCAGCTCCCCATCTTGATGAGTTTCTTGACAGACCCTTGCATATGTAATTTTAAAATCATTTAATAGCTGAAATAAATAGTCTATGACGAATAATGGAATAAGAGGGCATTTTGGGTATGTAAGGAAAATTGATTTTCCCTGTAGGCGGAAGGTGTTTGGTGTTCTTGGCATTTTTCTCTCTATTATATTCTATTACTATGGCTTTGCGGAGTCAGAGCCAATTTATAGTCGAAGGTGTTAAATGGGCTTTGTGGCTCTATTCATGTGAGCCGTTGATTGTTGTAGTACGTGGCAGAAATCCGTGAAGGGGCAAAGCCATATAATATT

Gene Information

NCBI Accession YP_009448197.1
Location 224-523
Gene Name V3
Protein Name putative ssDNA-dsDNA regulatory protein
Coding Region ATGGACTGGACCTTTAACGCCTGGGTCTATCTATTTGTTTTTATAAGTACAGTTATAATTACTGTATTTAATGGAGTTACCAGTATACAGCTCCTCAGAATATCCGAAAAGTTACAACGCATTTCTGCAGACTTGCGCGGATCGATTAGTCACCTGGCAATTACAATTGGTGTGGCAGAAGGTCGAGTATTTCAACCGTCACAAGGCGGACGAGTTCTTCGAGTGGGAAGAACTGTATCAGTTCCTAATAGAGTTCAGGAAGACCGTCCGACGGGCGGGGAGACGCAAGTCTCACCATAA
Protein Sequence MDWTFNAWVYLFVFISTVIITVFNGVTSIQLLRISEKLQRISADLRGSISHLAITIGVAEGRVFQPSQGGRVLRVGRTVSVPNRVQEDRPTGGETQVSP

NCBI Accession YP_009448198.1
Location 294-650
Gene Name V2
Protein Name putative movement protein
Coding Region ATGGAGTTACCAGTATACAGCTCCTCAGAATATCCGAAAAGTTACAACGCATTTCTGCAGACTTGCGCGGATCGATTAGTCACCTGGCAATTACAATTGGTGTGGCAGAAGGTCGAGTATTTCAACCGTCACAAGGCGGACGAGTTCTTCGAGTGGGAAGAACTGTATCAGTTCCTAATAGAGTTCAGGAAGACCGTCCGACGGGCGGGGAGACGCAAGTCTCACCATAAAAAAATAGAAATCTATAATCTCTTTTGGATCAAAAGAGATGGGAGCAAATCAGGCGTTAATAAGTTGGGGTGCGAAGAAAAAGCGAAGTACTCCAAACCGTTCGAGTTGGACTCGGAGAGTTCGTAG
Protein Sequence MELPVYSSSEYPKSYNAFLQTCADRLVTWQLQLVWQKVEYFNRHKADEFFEWEELYQFLIEFRKTVRRAGRRKSHHKKIEIYNLFWIKRDGSKSGVNKLGCEEKAKYSKPFELDSESS

NCBI Accession YP_009448199.1
Location 562-1302
Gene Name V1
Protein Name putative coat protein
Coding Region ATGGGAGCAAATCAGGCGTTAATAAGTTGGGGTGCGAAGAAAAAGCGAAGTACTCCAAACCGTTCGAGTTGGACTCGGAGAGTTCGTAGGCGTCTTTCTTATTACCCTAGGTATATACCTAGGGGTCCTAAAAAAAATACCCGTGATAAGGTGTATACCTTTACAAGTTATAAGGCCTTTAGCGATTTAGGTGGTGTATGGTTGTTAAATGGTTTTGCCCAAGGTTTGGGTAATAACCAAAGAAATGGAAGCGTTGAAATTATTCGCGCTTTAAATTTGCGTTTAGGTGTTGCTATAGCAGAAGGTGCCACAGCATTAAATTTTGCTAGGGACTGGAACTGTACATGGTATGTAATTGCAGACCAGAGTCCTGGCACAACTATTCCAGCATTTACAGACATTTTTACCACAGGTTCTGCTGCTGTTGATGGTCTGGAATATATTCCAGATGATATGCATCTTCGTTTTCAGATTAAGATGAAGGGTAAATTGAAGTTCATTACTTCTGGAGTTAGTTATTCTACAGCAGTTACTTCCAAAACTGGCTACAATAAGTGCCATGATATTGTTAGAAAATTTAAATCAAAGTTGAATGTAAGAACTGATTATGATAGTAACAGTTCTGGAGGTGCTATTACAGATATAAAAAAGGGTGCTTTGTATTTAGTTATTAATCCTGAATTCAGCTGTTATGCTGGTGTAAATTGCACTATTTATCATAGTGGTCCTTATTATAAATAA
Protein Sequence MGANQALISWGAKKKRSTPNRSSWTRRVRRRLSYYPRYIPRGPKKNTRDKVYTFTSYKAFSDLGGVWLLNGFAQGLGNNQRNGSVEIIRALNLRLGVAIAEGATALNFARDWNCTWYVIADQSPGTTIPAFTDIFTTGSAAVDGLEYIPDDMHLRFQIKMKGKLKFITSGVSYSTAVTSKTGYNKCHDIVRKFKSKLNVRTDYDSNSSGGAITDIKKGALYLVINPEFSCYAGVNCTIYHSGPYYK

NCBI Accession YP_009448200.1
Location 1568-1957,2109-2717
Gene Name C1:C2
Protein Name putative replication associated protein
Coding Region ATGCCAAGAACACCAAACACCTTCCGCCTACAGGGAAAATCAATTTTCCTTACATACCCAAAATGCCCTCTTATTCCATTATTCGTCATAGACTATTTATTTCAGCTATTAAATGATTTTAAAATTACATATGCAAGGGTCTGTCAAGAAACTCATCAAGATGGGGAGCTGCATCTCCACTGCCTCGTCCAATTGGAGGAGAAGTTCAGTACAAGAAACCCAAGATTCTTCGACATTTCAGACCCTAATAGAGAGAGCACATACCATCCAAACGCCCAGATTCCAAGAAGGGACGCTGACGTTGCAGACTACATCGCTAAGGGAGGAGTATATGAGGAACGAGGATTACTTAGAGCTTCAAGACGCAGTCCTAAGAAATCTCGGGATACTATATGGGGAAAGATCATCGAGGAATCCACTAACGCCGAGGACTTCCTCAGCAGATGTCAACGAGAACAACCTTATACATACGCAACACAACTGCGAAACCTCGAATACATGGCCAACAAAAAGTGGCCAAAACCAAGTGCGAATTTTACACCCAAATTCTCAATATTCAATGGCGTACCCGAGCCCATTAAAAATTGGGTAGAACAGAACATATGCGTGGACCCGGAGAATAAGCCCGATAGGCCATTAACACTCATTGTTGAAGGCCCAACAAGAACAGGTAAAACAGCATGGGCAAGAAGCTTCGGACTACACAATTATTTCTGCGGAGGAGTGAACTGGACTGAGTACAATCCCCACGCTATATATAATGTTTTCGACGACATACCATTTCAATACTTGCCGTGCAAAAAGGAAATACTTGGAGCACAAAAAGATTTCACGGTTAATGAAAAGTATAGGAAAAAATGTACAATAAAAGGAGGCATTCCTTCAATAGTATTATGTAATCCTGATAGCTCTTATAAGGAGGCTATTAGTCGTTCTGATTTGTATGTTTGGTGTCAGTCTAATGTCCTTTATGAGTTCATTGATGGATCGCTTTTTTAG
Protein Sequence MPRTPNTFRLQGKSIFLTYPKCPLIPLFVIDYLFQLLNDFKITYARVCQETHQDGELHLHCLVQLEEKFSTRNPRFFDISDPNRESTYHPNAQIPRRDADVADYIAKGGVYEERGLLRASRRSPKKSRDTIWGKIIEESTNAEDFLSRCQREQPYTYATQLRNLEYMANKKWPKPSANFTPKFSIFNGVPEPIKNWVEQNICVDPENKPDRPLTLIVEGPTRTGKTAWARSFGLHNYFCGGVNWTEYNPHAIYNVFDDIPFQYLPCKKEILGAQKDFTVNEKYRKKCTIKGGIPSIVLCNPDSSYKEAISRSDLYVWCQSNVLYEFIDGSLF

NCBI Accession YP_009448201.1
Location 1944-2717
Gene Name C1
Protein Name RepA
Coding Region ATGCCAAGAACACCAAACACCTTCCGCCTACAGGGAAAATCAATTTTCCTTACATACCCAAAATGCCCTCTTATTCCATTATTCGTCATAGACTATTTATTTCAGCTATTAAATGATTTTAAAATTACATATGCAAGGGTCTGTCAAGAAACTCATCAAGATGGGGAGCTGCATCTCCACTGCCTCGTCCAATTGGAGGAGAAGTTCAGTACAAGAAACCCAAGATTCTTCGACATTTCAGACCCTAATAGAGAGAGCACATACCATCCAAACGCCCAGATTCCAAGAAGGGACGCTGACGTTGCAGACTACATCGCTAAGGGAGGAGTATATGAGGAACGAGGATTACTTAGAGCTTCAAGACGCAGTCCTAAGAAATCTCGGGATACTATATGGGGAAAGATCATCGAGGAATCCACTAACGCCGAGGACTTCCTCAGCAGATGTCAACGAGAACAACCTTATACATACGCAACACAACTGCGAAACCTCGAATACATGGCCAACAAAAAGTGGCCAAAACCAAGTGCGAATTTTACACCCAAATTCTCAATATTCAATGGCGTACCCGAGCCCATTAAAAATTGGGTAGAACAGAACATATGCGTGGTACATAGAGATTTCATTTTGTTAGACGTTCCACAATTAACACAAAATGATTTAGATTTTTACGATAGTATGGCACAAGAATCTATAGAACAGATTCTTGAAAACCCAGATAACTTTACTAACATTAGACCACACATTTATAATGATTCAGGACCCGGAGAATAA
Protein Sequence MPRTPNTFRLQGKSIFLTYPKCPLIPLFVIDYLFQLLNDFKITYARVCQETHQDGELHLHCLVQLEEKFSTRNPRFFDISDPNRESTYHPNAQIPRRDADVADYIAKGGVYEERGLLRASRRSPKKSRDTIWGKIIEESTNAEDFLSRCQREQPYTYATQLRNLEYMANKKWPKPSANFTPKFSIFNGVPEPIKNWVEQNICVVHRDFILLDVPQLTQNDLDFYDSMAQESIEQILENPDNFTNIRPHIYNDSGPGE

NCBI Accession YP_009448202.1
Location 2126-2605
Gene Name C3
Protein Name C3
Coding Region ATGATTTTAAAATTACATATGCAAGGGTCTGTCAAGAAACTCATCAAGATGGGGAGCTGCATCTCCACTGCCTCGTCCAATTGGAGGAGAAGTTCAGTACAAGAAACCCAAGATTCTTCGACATTTCAGACCCTAATAGAGAGAGCACATACCATCCAAACGCCCAGATTCCAAGAAGGGACGCTGACGTTGCAGACTACATCGCTAAGGGAGGAGTATATGAGGAACGAGGATTACTTAGAGCTTCAAGACGCAGTCCTAAGAAATCTCGGGATACTATATGGGGAAAGATCATCGAGGAATCCACTAACGCCGAGGACTTCCTCAGCAGATGTCAACGAGAACAACCTTATACATACGCAACACAACTGCGAAACCTCGAATACATGGCCAACAAAAAGTGGCCAAAACCAAGTGCGAATTTTACACCCAAATTCTCAATATTCAATGGCGTACCCGAGCCCATTAAAAATTGGGTAG
Protein Sequence MILKLHMQGSVKKLIKMGSCISTASSNWRRSSVQETQDSSTFQTLIERAHTIQTPRFQEGTLTLQTTSLREEYMRNEDYLELQDAVLRNLGILYGERSSRNPLTPRTSSADVNENNLIHTQHNCETSNTWPTKSGQNQVRILHPNSQYSMAYPSPLKIG

References More References in PubMed

1

First Report of Tomato Yellow Leaf Curl Virus Infecting Upland Cotton (Gossypium hirsutum) in Alabama, USA.

McLaughlin A, et al.  Plant Dis. 2022 Apr 12. doi: 10.1094/PDIS-09-20-2041-PDN. Online ahead of print.

PMID: 35412338
2

Tomato Apical Leaf Curl Virus: A Novel, Monopartite Geminivirus Detected in Tomatoes in Argentina.

Vaghi Medina CG, et al.  Front Microbiol. 2018 Jan 12;8:2665. doi: 10.3389/fmicb.2017.02665. eCollection 2017.

PMID: 29375528
3

Molecular characterization and infectivity analysis of tomato leaf curl New Delhi virus isolates infecting potato.

Jeevalatha A, et al.  3 Biotech. 2021 Apr;11(4):203. doi: 10.1007/s13205-021-02752-5. Epub 2021 Mar 30.

PMID: 33927993
4

Investigating the Interplay between Tomato Leaf Curl New Delhi Virus Infection, Starch Metabolism and Antioxidant Defence System in Potato (Solanum tuberosum L.).

Kumar R, et al.  Antioxidants (Basel). 2023 Jul 18;12(7):1447. doi: 10.3390/antiox12071447.

PMID: 37507984
5

First report of Tomato brown rugose fruit virus in tomato in Spain.

Alfaro-Fernández A, et al.  Plant Dis. 2020 Sep 23. doi: 10.1094/PDIS-06-20-1251-PDN. Online ahead of print.

PMID: 32967554
6

An insight into differentially regulated genes in resistant and susceptible genotypes of potato in response to tomato leaf curl New Delhi virus-[potato] infection.

Jeevalatha A, et al.  Virus Res. 2017 Mar 15;232:22-33. doi: 10.1016/j.virusres.2017.01.015. Epub 2017 Jan 20.

PMID: 28115198
7

RNA-seq analysis reveals an early defense response to tomato leaf curl New Delhi virus in potato cultivar Kufri Bahar.

Jeevalatha A, et al.  Funct Integr Genomics. 2023 Jun 30;23(3):215. doi: 10.1007/s10142-023-01138-5.

PMID: 37389664
8

Uniplex and duplex PCR detection of geminivirus associated with potato apical leaf curl disease in India.

Jeevalatha A, et al.  J Virol Methods. 2013 Oct;193(1):62-7. doi: 10.1016/j.jviromet.2013.05.012. Epub 2013 May 24.

PMID: 23711886
9

Effect of potato apical leaf curl disease on glycemic index and resistant starch of potato (Solanum tuberosum L.) tubers.

Lal MK, et al.  Food Chem. 2021 Oct 15;359:129939. doi: 10.1016/j.foodchem.2021.129939. Epub 2021 Apr 23.

PMID: 33957333
10

Infection of tomato by the tomato yellow leaf curl virus: susceptibility to infection, symptom development, and accumulation of viral DNA.

Ber R, et al.  Arch Virol. 1990;112(3-4):169-80. doi: 10.1007/BF01323162.

PMID: 2378566