Beet curly top virus

Basic Information

Genus	Curtovirus
NCBI Assembly	GCF_000843505.1
Release date	2018/11/26
Submitter	Stanley,J., Markham,P.G., Callis,R.J., Pinner,M.S.
Download	Genome \|GFF3 \|PEP \|CDS

Genomic Organization

JBrowse

Genome

NC_001412

TGTACTCCGATGACGTGGCTTAGCATATTAACATATCTATTGGAGTATTGGAGTATTATATATATTAGTACAACTTTCATAAGGGCCATCCGTTATAATATTACCGGATGGCCCGAAAAAAATGGGCACCCAATCAAAACGTGACACGTGGAAGGGGACTGTTGAATGATGTGACGTTTTTGAGCGGGAAACTTCCTGAAGAAGATTCCTGCGGGAAACTTCCTGAAGAAGATTCCTTTCAGATAAGATTTGTTGACTGGTCAAAAGAAGGGGACAACTTTATTAAAGTAACTTTACTTTAGTAAAAGTAAAGTAAGTGTGCCCCACAGGAAACTTGCTCAGCAAGTTTTGAATTATGTCGTTTTATATACGTTATTTTTACATGTATATGTAATTATAAATGATGGTCTGTCTACCAGACTGGTTATTTTTGCTATTTATCTTCAGTATTCTACTGCAATCAGGTACGAACTTTTATGGGACCTTTCAGAGTGGATCAATTTCCAGACAATTATCCAGCCTTTCTAGCAGTATCGACCAGTTGTTTCTTAAGGTACAACAGGTGGTGTATACTAGGTATCCATCAAGAGATAGGGTCTCTGACCCTAGAAGAAGGCGAGGTCTTTCGTCAATTCCAGAAGGAAGTGAAGAAGCTACTGAGGTGTAAGGTTAATTTTCATAGGAAGTGTTCGTTGTATGAGGAAATATACAAGAAATACGTATACAATGTCCCAGAAAAGAAAGGTGAATCCTCAAAGTGCGTGGCCGAAGAAGAGGAGGACTAGTACGACTTCGAGGAAATACCAATGGAGGAGACCTGTGACAAAAAACAGGACTCTGAAGTTAAAGATGTATGATGATATGTTGGGTGCTGGTGGTATAGGATCTACCATTAGTAATAATGGTATGATTACTATGTTGAATAATTATGTCCAGGGTATTGGTGATAGTCAGAGAGCGAAGAACGTTACTGTGACGAAGCATTTGAAGTTTGATATGGCTCTTATGGGGAGTTCTCAGTTCTGGGAGACTCCTAATTATATGACCCAATATCATTGGATTATCATAGACAAGGATGTTGGGTCAGTGTTTCCTACTAAGTTATCGAGTATATTTGATATTCCCGATAACGGTCAGGCTATGCCGTCTACTTATCGTATTCGAAGAGATATGAACGAGAGGTTTATTGGGAAGAAGAAATGGAGAACTCATTGGATGTCTACTGGTACTGGATATGGAGGGAAGGAGACTTACAAGGCTCCTTCAATGCCAAATTACAAGAAACCGATGAATATCAATGTGCGCAATTTGAACATGAGGACTATTTGGAAAGACACCGGTGGTGGGAAGTATGAAGACGTGAAGGAGAATGCTTTACTCTATGTTGTTGTTAATGATAATACGGATAATACTAATATGTATGCCACATTATTTGGCAATTGTAGATGCTATTTTTATTAATAATATTTATTATTAATAATGAAATTAGTACAAGTTCATTGCAACACTCTGGTTCTGAATTACACTTGATACAAAAGTAAATTCTTCATACAGGACATGATTTAAACCTCTAATTACATTATTAATACAAATTAAACCTAGATTATCCAAGTATATCTCTAGTCTCTTTTTCAAGACCTTCAAGAAACGGGGTCCAGTCAATATCCTGTTCGATCCAGTTATCGTCAGCTCTATCCAGCACTTGTGAAGATTCAACGCTCTCCGGAGGTTGTAGTTGAATCTGATTTGTATCTTCAGTTGATAGATTGGCCCGTATCTCTCGAACCATAGGAGTTTCATATACAGTGGATTCGGTACATTCTCGAATTCGACGGAATTTGTTGCCTGATGGAGAGTAATAGGTTCCCCTGTGCGAAAATCCTCTATTACATTCATGGTGTATTGTGAAGTGGCAGTTACAGGGTAGAGTCACCTTGCGAGGATGCTGCTGCTTGGTTATTAAAGAGCGGACCTTGGAGTTTGCAGAAGGTTGAATTATGTAATGTCCAGGACTTAAGGGCTTCATTTTCTGGTTTTTCAAGAAATTGTTGGTATGAGCTCTCAGGTCCTGGATTGCATAATATAATGCAGGGGATACCACCTTTAATGACACGTGGTTTTCCATACTTTAAGTTTGTCTGCCACTCCTTTTGTGCTCCAATAAGGTGTTTCCAGTGTTTCATCTTTAAGTAAGTGGGATCTACGTCATCAATGACGTTGTATTCCACTTCATCATAATACGTTCTAGGGCTAAAATCTAAGTGCCCTGTGATGTAATTGTGGGCCCCTAAAGATCTAGCCCACATAGTCTTCCCTGTTCTTGAATCACCCTCTACTATGATACTATTATATCTTAAAGGCCGCGCAGCGGCATCAACCCCGAAATATGCATCAGCCCATTCTTGCATTTCCTCAGGAACGTTTGTGAATGAGGACAGAGGAAATAGTGGAGTCCATGGATCAGGTGGCCTCTGAAATATCTTTTGAGCATTGTTCAAAAGATTGTGATGTTGAAGGAAGTAATCCTTTGGTTGTTCTTCCTTCAATATTTGAAGTGCTTGGTCAAGAGAAGTTGCGTTTAACGCCTTGGCATATGAGTCGTTAGCTGTCTGTTGACCTCCTCTAGCACTTCTACCGTCGATCTGGAATTCTCCCCATTCAATTGTGTCTCCGTCCTTGTCGACGTAGGACTTGACGTCGGAGCTGGATTTAGCTCTCTGAATGTTTGGATGGAAATGTGCTGACCTGGTTGGGGATACCAGGTCGAATAATCTGATATTTGTGATCTGAACTTTTCCTTCGAGTTGAAGCAGGACGTGGAGATGAGGTTGCCCATCTTCGTGTAGCTCTCTGGCAATTTTAATATATTTTTTATTAGATGAAAGTTGTATTCTTTGAATTTGCTCAAGAGCTTCTTCTTTTGAAAGAGAACACTGAGGATATGTAAGAAATATGTTTTTTGCTTGAATACGAAATCTTTTAGTAGGAGGCATN

Gene Information

NCBI Accession	NP_040557.1
Location	1917-2994,1-80
Protein Name	replication-associated protein
Coding Region	ATGAAAGTTGTACTAATATATATAATACTCCAATACTCCAATAGATATGTTAATATGCTAAGCCACGTCATCGGAGTACANATGCCTCCTACTAAAAGATTTCGTATTCAAGCAAAAAACATATTTCTTACATATCCTCAGTGTTCTCTTTCAAAAGAAGAAGCTCTTGAGCAAATTCAAAGAATACAACTTTCATCTAATAAAAAATATATTAAAATTGCCAGAGAGCTACACGAAGATGGGCAACCTCATCTCCACGTCCTGCTTCAACTCGAAGGAAAAGTTCAGATCACAAATATCAGATTATTCGACCTGGTATCCCCAACCAGGTCAGCACATTTCCATCCAAACATTCAGAGAGCTAAATCCAGCTCCGACGTCAAGTCCTACGTCGACAAGGACGGAGACACAATTGAATGGGGAGAATTCCAGATCGACGGTAGAAGTGCTAGAGGAGGTCAACAGACAGCTAACGACTCATATGCCAAGGCGTTAAACGCAACTTCTCTTGACCAAGCACTTCAAATATTGAAGGAAGAACAACCAAAGGATTACTTCCTTCAACATCACAATCTTTTGAACAATGCTCAAAAGATATTTCAGAGGCCACCTGATCCATGGACTCCACTATTTCCTCTGTCCTCATTCACAAACGTTCCTGAGGAAATGCAAGAATGGGCTGATGCATATTTCGGGGTTGATGCCGCTGCGCGGCCTTTAAGATATAATAGTATCATAGTAGAGGGTGATTCAAGAACAGGGAAGACTATGTGGGCTAGATCTTTAGGGGCCCACAATTACATCACAGGGCACTTAGATTTTAGCCCTAGAACGTATTATGATGAAGTGGAATACAACGTCATTGATGACGTAGATCCCACTTACTTAAAGATGAAACACTGGAAACACCTTATTGGAGCACAAAAGGAGTGGCAGACAAACTTAAAGTATGGAAAACCACGTGTCATTAAAGGTGGTATCCCCTGCATTATATTATGCAATCCAGGACCTGAGAGCTCATACCAACAATTTCTTGAAAAACCAGAAAATGAAGCCCTTAAGTCCTGGACATTACATAATTCAACCTTCTGCAAACTCCAAGGTCCGCTCTTTAATAACCAAGCAGCAGCATCCTCGCAAGGTGACTCTACCCTGTAA
Protein Sequence	MKVVLIYIILQYSNRYVNMLSHVIGVXMPPTKRFRIQAKNIFLTYPQCSLSKEEALEQIQRIQLSSNKKYIKIARELHEDGQPHLHVLLQLEGKVQITNIRLFDLVSPTRSAHFHPNIQRAKSSSDVKSYVDKDGDTIEWGEFQIDGRSARGGQQTANDSYAKALNATSLDQALQILKEEQPKDYFLQHHNLLNNAQKIFQRPPDPWTPLFPLSSFTNVPEEMQEWADAYFGVDAAARPLRYNSIIVEGDSRTGKTMWARSLGAHNYITGHLDFSPRTYYDEVEYNVIDDVDPTYLKMKHWKHLIGAQKEWQTNLKYGKPRVIKGGIPCIILCNPGPESSYQQFLEKPENEALKSWTLHNSTFCKLQGPLFNNQAAASSQGDSTL

NCBI Accession	NP_899663.1
Location	401-667
Protein Name	movement protein
Coding Region	ATGATGGTCTGTCTACCAGACTGGTTATTTTTGCTATTTATCTTCAGTATTCTACTGCAATCAGGTACGAACTTTTATGGGACCTTTCAGAGTGGATCAATTTCCAGACAATTATCCAGCCTTTCTAGCAGTATCGACCAGTTGTTTCTTAAGGTACAACAGGTGGTGTATACTAGGTATCCATCAAGAGATAGGGTCTCTGACCCTAGAAGAAGGCGAGGTCTTTCGTCAATTCCAGAAGGAAGTGAAGAAGCTACTGAGGTGTAA
Protein Sequence	MMVCLPDWLFLLFIFSILLQSGTNFYGTFQSGSISRQLSSLSSSIDQLFLKVQQVVYTRYPSRDRVSDPRRRRGLSSIPEGSEEATEV

NCBI Accession	NP_040558.1
Location	477-785
Protein Name	hypothetical protein
Coding Region	ATGGGACCTTTCAGAGTGGATCAATTTCCAGACAATTATCCAGCCTTTCTAGCAGTATCGACCAGTTGTTTCTTAAGGTACAACAGGTGGTGTATACTAGGTATCCATCAAGAGATAGGGTCTCTGACCCTAGAAGAAGGCGAGGTCTTTCGTCAATTCCAGAAGGAAGTGAAGAAGCTACTGAGGTGTAAGGTTAATTTTCATAGGAAGTGTTCGTTGTATGAGGAAATATACAAGAAATACGTATACAATGTCCCAGAAAAGAAAGGTGAATCCTCAAAGTGCGTGGCCGAAGAAGAGGAGGACTAG
Protein Sequence	MGPFRVDQFPDNYPAFLAVSTSCFLRYNRWCILGIHQEIGSLTLEEGEVFRQFQKEVKKLLRCKVNFHRKCSLYEEIYKKYVYNVPEKKGESSKCVAEEEED

NCBI Accession	NP_040559.1
Location	697-1461
Protein Name	coat protein
Coding Region	ATGAGGAAATATACAAGAAATACGTATACAATGTCCCAGAAAAGAAAGGTGAATCCTCAAAGTGCGTGGCCGAAGAAGAGGAGGACTAGTACGACTTCGAGGAAATACCAATGGAGGAGACCTGTGACAAAAAACAGGACTCTGAAGTTAAAGATGTATGATGATATGTTGGGTGCTGGTGGTATAGGATCTACCATTAGTAATAATGGTATGATTACTATGTTGAATAATTATGTCCAGGGTATTGGTGATAGTCAGAGAGCGAAGAACGTTACTGTGACGAAGCATTTGAAGTTTGATATGGCTCTTATGGGGAGTTCTCAGTTCTGGGAGACTCCTAATTATATGACCCAATATCATTGGATTATCATAGACAAGGATGTTGGGTCAGTGTTTCCTACTAAGTTATCGAGTATATTTGATATTCCCGATAACGGTCAGGCTATGCCGTCTACTTATCGTATTCGAAGAGATATGAACGAGAGGTTTATTGGGAAGAAGAAATGGAGAACTCATTGGATGTCTACTGGTACTGGATATGGAGGGAAGGAGACTTACAAGGCTCCTTCAATGCCAAATTACAAGAAACCGATGAATATCAATGTGCGCAATTTGAACATGAGGACTATTTGGAAAGACACCGGTGGTGGGAAGTATGAAGACGTGAAGGAGAATGCTTTACTCTATGTTGTTGTTAATGATAATACGGATAATACTAATATGTATGCCACATTATTTGGCAATTGTAGATGCTATTTTTATTAA
Protein Sequence	MRKYTRNTYTMSQKRKVNPQSAWPKKRRTSTTSRKYQWRRPVTKNRTLKLKMYDDMLGAGGIGSTISNNGMITMLNNYVQGIGDSQRAKNVTVTKHLKFDMALMGSSQFWETPNYMTQYHWIIIDKDVGSVFPTKLSSIFDIPDNGQAMPSTYRIRRDMNERFIGKKKWRTHWMSTGTGYGGKETYKAPSMPNYKKPMNINVRNLNMRTIWKDTGGGKYEDVKENALLYVVVNDNTDNTNMYATLFGNCRCYFY

NCBI Accession	NP_040560.1
Location	1486-1896
Protein Name	replication enhancer protein
Coding Region	ATGAATGTAATAGAGGATTTTCGCACAGGGGAACCTATTACTCTCCATCAGGCAACAAATTCCGTCGAATTCGAGAATGTACCGAATCCACTGTATATGAAACTCCTATGGTTCGAGAGATACGGGCCAATCTATCAACTGAAGATACAAATCAGATTCAACTACAACCTCCGGAGAGCGTTGAATCTTCACAAGTGCTGGATAGAGCTGACGATAACTGGATCGAACAGGATATTGACTGGACCCCGTTTCTTGAAGGTCTTGAAAAAGAGACTAGAGATATACTTGGATAATCTAGGTTTAATTTGTATTAATAATGTAATTAGAGGTTTAAATCATGTCCTGTATGAAGAATTTACTTTTGTATCAAGTGTAATTCAGAACCAGAGTGTTGCAATGAACTTGTACTAA
Protein Sequence	MNVIEDFRTGEPITLHQATNSVEFENVPNPLYMKLLWFERYGPIYQLKIQIRFNYNLRRALNLHKCWIELTITGSNRILTGPRFLKVLKKRLEIYLDNLGLICINNVIRGLNHVLYEEFTFVSSVIQNQSVAMNLY

NCBI Accession	NP_040561.1
Location	1604-2125
Protein Name	pathogenicity determinant protein
Coding Region	ATGGAAAACCACGTGTCATTAAAGGTGGTATCCCCTGCATTATATTATGCAATCCAGGACCTGAGAGCTCATACCAACAATTTCTTGAAAAACCAGAAAATGAAGCCCTTAAGTCCTGGACATTACATAATTCAACCTTCTGCAAACTCCAAGGTCCGCTCTTTAATAACCAAGCAGCAGCATCCTCGCAAGGTGACTCTACCCTGTAACTGCCACTTCACAATACACCATGAATGTAATAGAGGATTTTCGCACAGGGGAACCTATTACTCTCCATCAGGCAACAAATTCCGTCGAATTCGAGAATGTACCGAATCCACTGTATATGAAACTCCTATGGTTCGAGAGATACGGGCCAATCTATCAACTGAAGATACAAATCAGATTCAACTACAACCTCCGGAGAGCGTTGAATCTTCACAAGTGCTGGATAGAGCTGACGATAACTGGATCGAACAGGATATTGACTGGACCCCGTTTCTTGAAGGTCTTGAAAAAGAGACTAGAGATATACTTGGATAA
Protein Sequence	MENHVSLKVVSPALYYAIQDLRAHTNNFLKNQKMKPLSPGHYIIQPSANSKVRSLITKQQHPRKVTLPCNCHFTIHHECNRGFSHRGTYYSPSGNKFRRIRECTESTVYETPMVREIRANLSTEDTNQIQLQPPESVESSQVLDRADDNWIEQDIDWTPFLEGLEKETRDILG

References More References in PubMed

1	Pest categorisation of Beet curly top virus (non-EU isolates). EFSA Panel on Plant Health (PLH), et al. EFSA J. 2017 Oct 11;15(10):e04998. doi: 10.2903/j.efsa.2017.4998. eCollection 2017 Oct. PMID: 32625295
2	First Report of Beet Curly Top Virus Infecting Industrial Hemp (Cannabis sativa) in Arizona. Hu J, et al. Plant Dis. 2020 Dec 14. doi: 10.1094/PDIS-11-20-2330-PDN. Online ahead of print. PMID: 33315484
3	Regulatory Roles of Small Non-coding RNAs in Sugar Beet Resistance Against Beet curly top virus. Majumdar R, et al. Front Plant Sci. 2022 Jan 10;12:780877. doi: 10.3389/fpls.2021.780877. eCollection 2021. PMID: 35082811
4	Beet curly top virus Strains Associated with Sugar Beet in Idaho, Oregon, and a Western U.S. Collection. Strausbaugh CA, et al. Plant Dis. 2017 Aug;101(8):1373-1382. doi: 10.1094/PDIS-03-17-0381-RE. Epub 2017 May 25. PMID: 30678603
5	Complementary-sense gene regulation in beet curly top virus-SpCT. Guerrero J, et al. Arch Virol. 2019 Nov;164(11):2823-2828. doi: 10.1007/s00705-019-04385-9. Epub 2019 Sep 4. PMID: 31485748
6	Beet Curly Top Iran Virus Rep and V2 Suppress Post-Transcriptional Gene Silencing via Distinct Modes of Action. Ebrahimi S, et al. Viruses. 2023 Sep 26;15(10):1996. doi: 10.3390/v15101996. PMID: 37896771
7	Curly Top Disease of Hemp (Cannabis sativa) in California Is Caused by Mild-Type Strains of Beet curly top virus Often in Mixed Infection. Melgarejo TA, et al. Plant Dis. 2022 Dec;106(12):3022-3026. doi: 10.1094/PDIS-04-22-0856-SC. Epub 2022 Nov 17. PMID: 35549320
8	First report of Pepper yellow dwarf strain of Beet curly top virus and Spinach curly top Arizona virus in red table beet in Idaho, United States. Ramachandran V, et al. Plant Dis. 2023 Apr 27. doi: 10.1094/PDIS-12-22-2855-PDN. Online ahead of print. PMID: 37102723
9	Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components. Eini O, et al. N Biotechnol. 2022 Mar 25;67:1-11. doi: 10.1016/j.nbt.2021.12.002. Epub 2021 Dec 8. PMID: 34896246
10	First Report of Curly Top of Coriandrum sativum Caused by Beet curly top virus in the Columbia Basin of Washington State. Swisher Grimm KD, et al. Plant Dis. 2021 Apr 6. doi: 10.1094/PDIS-01-21-0041-PDN. Online ahead of print. PMID: 33823609