Tomato leaf curl Kerala virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_000881415.1
Isolate India
Release date 2015/2/22
Submitter Mukhopadhyay,S., Pandey,P., Nazeem,P.A., Mukherjee,S.K.
Host
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_011135
ACCGGATGGCCGCGAATTTTTTTGTGGGCCCCACAACGCACTAACTGACAACGACTAGTGGACCAATCACATGACGCGCTCAAAGCTTAATTGTTTTGTGGTCCCCTATTTATACTTCGGCACTAAGTATTGTACATTGCAAAATGTGGGATCCATTGTTAAACGAATTTCCCGACACTGTTCACGGTTTTAGATGTATGTTAGCAATTAAATATCTACAGTTAGTAGAAAACACTTATTCTCCTGATACATTAGGTTACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGAAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACACCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAGTCAAGAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGCCCAGATGTCCCTAGAGGATGTGAAGGCCCATGTAAGGTACAATCATTTGAGCAAAGGCATGATATTTCTCATATTGGGAAGGTCATGTGTATTAGTGACGTTACTCGTGGGATTGGGCTAACTCATAGGGTTGGTAAGCGTTTCTGTGTTAAATCCGTTTACGTTTTGGGTAAGATATGGATGGATGAGAATATCAAGACCAAGAATCACACGAATAGTGTTATGTTTTTTCTTGTTCGTGATCGTCGTCCTGTTGACAAGCCACAAGACTTTGGAGAGGTGTTCAATATGTTTGACAATGAGCCTAGCACTGCTACTGTGAAGAATGTGCATCGAGATCGTTATCATGTTTTGAGGAAGTGGCATGCAACTGTCACTGGTGGTCAGTACGCTTCAAAGGAACAGGCATTAGTGAAGAAGTTTGTTAACGTAATAATTTATGTTGTTTATAACCAGCAAGAGGCTGGGAAATATGAGAATCATTCTGAGAATGCTTTGATGTTGTATATGGCATGTACTCATGCCTCTAATTCTGTGTACGCTACGCTGAAGATACGTATCTACTTCTATGATTCTGTAACAAACTGAATTAATAAAGATTGTATTTTATTGAATATGATTGGTCTACATATACAATGTGGTGTAATACATTCCATAATACATGATCAACAGCTCTAATTACATTGTTAATACTGATGACTCCTAAATTATTTAAATATTTATACACTTGGGTCTTAAAGACTCTTAAGAAACGACCAGTCTGAGGCTGTGAGGTCATCCAGATTCGGAAGACTAGGAAACATTTGTGTATCCCCAACACTTTCCTCAGGTTGTGATTGAACTGTACTTGGACGGTGATGATGTCTTGGTTCATCAGGAATGGCCGGTTGTGGTGTTCTGTTATCTTGAAAAATAGGGGATTTTGAATCTCCCAGATAAACACGCCATTCTCTGCTTGAGCTGCAGTGATGGGTTCCCCTGTGCGTGAATCCATGGTTGTGGCAGGCTAATGCAATGAAGTATGAACAGCCGCACGGTAGATCAACACGTCGACGCCTGGTCCCCTTCTTGGCTAGCCTGTGCTGCACTTTGATTGGTACCTGAGTACAGTGGGCCTTCGAGGGTGACGAAGATCGCATTCTTTAATGCCCAGTTTTTTAGTGCAGAATTCTTATCTTCATCCAAGAACTCTTTATAGCTGGAATTTGGTCCTGGATTGCAGAGGAAGATAGTGGGAATTCCGCCTTTAATTTGAACTGGCTTCCCGTACTTTGTATTTGATTGCCAGTCCCTTTGGGCCCCCATGAATTCTTTAAAGTGCTTTAGATAGTGGGGGTCTACGTCATCAATGACGTTATACCAGGCATCATTACTGTAGACCTTTGGACTAAGGTCTAAATGACCACACAGATAATTATGTGGTCCCAGTGATCTGGCCCACATAGTCTTTCCCGTACTACTATCACCCCTCATGACTATACTTACAGGTCTCAAAGGCCGCGCAGCGGCACTGACGACGTTCTCAGCAGCCCACTCTTCAAGTTCTTCTGGAACTTGATCAAGGAAGAAAGAAAAAAAGGGGGAAACATAACCTTCTTTAGGAAGTGTAAAATCCCTATCTAAATTAAGATCTAATAATGGAAATTGGAAAACAAAACCTTGGGGTGCTAATTCTTTAATTACTCTAAGAGCCTCTGACTTACTGCCTGCGTTAAGCGCTGCGGCGTAAGCATCATACGCTGACTGTGACCCCCCCTCTGCAGATCTCCATTCGATCTGAAACTCTCCCCAGTCGAGGGTGTCTCCGTCCTTCTCCAGATAGGACTTGACGTCTGAGCTTGATTTAGCTCCCTGAATGTTCGGATGGAAATGTGCTGACCTGGTTGGGGATACCAGGTCGAAGAATCTGTTATTTTGGCACTTGTATTTTCCTTCGAACTGGATGAGCACGTGAAGATGAGGTTCCCCATTTTCATGAAGCTCTCTGCAGATTTTTATGTATTTTTTGTTGGTTGGTGTTGCTAGGTTTTGTAATTGGGAAAGTGCTTCTTCTTTGGTGAGAGAGCATTTGGGATATGTTAGGAAATAATTTTTGGAGTTAATAAGGAAACGCTTTGGAGGCATGTTGACTAAGATAGAGGACCCGATTGACTGCTCTTGCAACTCTCCCCTGTATATCAGGTCTCAATATATAGTGAGACCCAAATGGCATAATGGTAATTAAAAAAACATTAATTTGAAATTCAAAACAAAAGGCTAAAGCGGCCATCCGTATAATATT

Gene Information

NCBI Accession YP_002124294.1
Location 144-500
Gene Name AV2
Protein Name pre-coat protein
Coding Region ATGTGGGATCCATTGTTAAACGAATTTCCCGACACTGTTCACGGTTTTAGATGTATGTTAGCAATTAAATATCTACAGTTAGTAGAAAACACTTATTCTCCTGATACATTAGGTTACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGAAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACACCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAGTCAAGAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGCCCAGATGTCCCTAG
Protein Sequence MWDPLLNEFPDTVHGFRCMLAIKYLQLVENTYSPDTLGYDLIRDLISVIRARNYVEATSRYNHFHTRFEGTPPSQLRQPICQPCCCPHCPRHKVKSMGEQAHEQKAQDVQDVQKPRCP

NCBI Accession YP_002124295.1
Location 304-1074
Gene Name AV1
Protein Name coat protein
Coding Region ATGTCGAAGCGACCAGCAGATATAATCATTTCCACACCCGCTTCGAAGGTACGCCGCCGTCTCAACTTCGACAGCCCATATGTCAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACAAAGTCAAGAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTACAGGATGTACAGAAGCCCAGATGTCCCTAGAGGATGTGAAGGCCCATGTAAGGTACAATCATTTGAGCAAAGGCATGATATTTCTCATATTGGGAAGGTCATGTGTATTAGTGACGTTACTCGTGGGATTGGGCTAACTCATAGGGTTGGTAAGCGTTTCTGTGTTAAATCCGTTTACGTTTTGGGTAAGATATGGATGGATGAGAATATCAAGACCAAGAATCACACGAATAGTGTTATGTTTTTTCTTGTTCGTGATCGTCGTCCTGTTGACAAGCCACAAGACTTTGGAGAGGTGTTCAATATGTTTGACAATGAGCCTAGCACTGCTACTGTGAAGAATGTGCATCGAGATCGTTATCATGTTTTGAGGAAGTGGCATGCAACTGTCACTGGTGGTCAGTACGCTTCAAAGGAACAGGCATTAGTGAAGAAGTTTGTTAACGTAATAATTTATGTTGTTTATAACCAGCAAGAGGCTGGGAAATATGAGAATCATTCTGAGAATGCTTTGATGTTGTATATGGCATGTACTCATGCCTCTAATTCTGTGTACGCTACGCTGAAGATACGTATCTACTTCTATGATTCTGTAACAAACTGA
Protein Sequence MSKRPADIIISTPASKVRRRLNFDSPYVSRAAAPIVRVTKSRAWANRPMNRKPRMYRMYRSPDVPRGCEGPCKVQSFEQRHDISHIGKVMCISDVTRGIGLTHRVGKRFCVKSVYVLGKIWMDENIKTKNHTNSVMFFLVRDRRPVDKPQDFGEVFNMFDNEPSTATVKNVHRDRYHVLRKWHATVTGGQYASKEQALVKKFVNVIIYVVYNQQEAGKYENHSENALMLYMACTHASNSVYATLKIRIYFYDSVTN

NCBI Accession YP_002124296.1
Location 1076-1480
Gene Name AC3
Protein Name AC3
Coding Region ATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCAGAGAATGGCGTGTTTATCTGGGAGATTCAAAATCCCCTATTTTTCAAGATAACAGAACACCACAACCGGCCATTCCTGATGAACCAAGACATCATCACCGTCCAAGTACAGTTCAATCACAACCTGAGGAAAGTGTTGGGGATACACAAATGTTTCCTAGTCTTCCGAATCTGGATGACCTCACAGCCTCAGACTGGTCGTTTCTTAAGAGTCTTTAAGACCCAAGTGTATAAATATTTAAATAATTTAGGAGTCATCAGTATTAACAATGTAATTAGAGCTGTTGATCATGTATTATGGAATGTATTACACCACATTGTATATGTAGACCAATCATATTCAATAAAATACAATCTTTATTAA
Protein Sequence MDSRTGEPITAAQAENGVFIWEIQNPLFFKITEHHNRPFLMNQDIITVQVQFNHNLRKVLGIHKCFLVFRIWMTSQPQTGRFLRVFKTQVYKYLNNLGVISINNVIRAVDHVLWNVLHHIVYVDQSYSIKYNLY

NCBI Accession YP_002124297.1
Location 1221-1625
Gene Name AC2
Protein Name AC2
Coding Region ATGCGATCTTCGTCACCCTCGAAGGCCCACTGTACTCAGGTACCAATCAAAGTGCAGCACAGGCTAGCCAAGAAGGGGACCAGGCGTCGACGTGTTGATCTACCGTGCGGCTGTTCATACTTCATTGCATTAGCCTGCCACAACCATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCAGAGAATGGCGTGTTTATCTGGGAGATTCAAAATCCCCTATTTTTCAAGATAACAGAACACCACAACCGGCCATTCCTGATGAACCAAGACATCATCACCGTCCAAGTACAGTTCAATCACAACCTGAGGAAAGTGTTGGGGATACACAAATGTTTCCTAGTCTTCCGAATCTGGATGACCTCACAGCCTCAGACTGGTCGTTTCTTAAGAGTCTTTAA
Protein Sequence MRSSSPSKAHCTQVPIKVQHRLAKKGTRRRRVDLPCGCSYFIALACHNHGFTHRGTHHCSSSREWRVYLGDSKSPIFQDNRTPQPAIPDEPRHHHRPSTVQSQPEESVGDTQMFPSLPNLDDLTASDWSFLKSL

NCBI Accession YP_002124298.1
Location 1528-2610
Gene Name AC1
Protein Name AC1
Coding Region ATGCCTCCAAAGCGTTTCCTTATTAACTCCAAAAATTATTTCCTAACATATCCCAAATGCTCTCTCACCAAAGAAGAAGCACTTTCCCAATTACAAAACCTAGCAACACCAACCAACAAAAAATACATAAAAATCTGCAGAGAGCTTCATGAAAATGGGGAACCTCATCTTCACGTGCTCATCCAGTTCGAAGGAAAATACAAGTGCCAAAATAACAGATTCTTCGACCTGGTATCCCCAACCAGGTCAGCACATTTCCATCCGAACATTCAGGGAGCTAAATCAAGCTCAGACGTCAAGTCCTATCTGGAGAAGGACGGAGACACCCTCGACTGGGGAGAGTTTCAGATCGAATGGAGATCTGCAGAGGGGGGGTCACAGTCAGCGTATGATGCTTACGCCGCAGCGCTTAACGCAGGCAGTAAGTCAGAGGCTCTTAGAGTAATTAAAGAATTAGCACCCCAAGGTTTTGTTTTCCAATTTCCATTATTAGATCTTAATTTAGATAGGGATTTTACACTTCCTAAAGAAGGTTATGTTTCCCCCTTTTTTTCTTTCTTCCTTGATCAAGTTCCAGAAGAACTTGAAGAGTGGGCTGCTGAGAACGTCGTCAGTGCCGCTGCGCGGCCTTTGAGACCTGTAAGTATAGTCATGAGGGGTGATAGTAGTACGGGAAAGACTATGTGGGCCAGATCACTGGGACCACATAATTATCTGTGTGGTCATTTAGACCTTAGTCCAAAGGTCTACAGTAATGATGCCTGGTATAACGTCATTGATGACGTAGACCCCCACTATCTAAAGCACTTTAAAGAATTCATGGGGGCCCAAAGGGACTGGCAATCAAATACAAAGTACGGGAAGCCAGTTCAAATTAAAGGCGGAATTCCCACTATCTTCCTCTGCAATCCAGGACCAAATTCCAGCTATAAAGAGTTCTTGGATGAAGATAAGAATTCTGCACTAAAAAACTGGGCATTAAAGAATGCGATCTTCGTCACCCTCGAAGGCCCACTGTACTCAGGTACCAATCAAAGTGCAGCACAGGCTAGCCAAGAAGGGGACCAGGCGTCGACGTGTTGA
Protein Sequence MPPKRFLINSKNYFLTYPKCSLTKEEALSQLQNLATPTNKKYIKICRELHENGEPHLHVLIQFEGKYKCQNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYLEKDGDTLDWGEFQIEWRSAEGGSQSAYDAYAAALNAGSKSEALRVIKELAPQGFVFQFPLLDLNLDRDFTLPKEGYVSPFFSFFLDQVPEELEEWAAENVVSAAARPLRPVSIVMRGDSSTGKTMWARSLGPHNYLCGHLDLSPKVYSNDAWYNVIDDVDPHYLKHFKEFMGAQRDWQSNTKYGKPVQIKGGIPTIFLCNPGPNSSYKEFLDEDKNSALKNWALKNAIFVTLEGPLYSGTNQSAAQASQEGDQASTC

NCBI Accession YP_002124299.1
Location 2166-2462
Gene Name AC4
Protein Name AC4
Coding Region ATGAAAATGGGGAACCTCATCTTCACGTGCTCATCCAGTTCGAAGGAAAATACAAGTGCCAAAATAACAGATTCTTCGACCTGGTATCCCCAACCAGGTCAGCACATTTCCATCCGAACATTCAGGGAGCTAAATCAAGCTCAGACGTCAAGTCCTATCTGGAGAAGGACGGAGACACCCTCGACTGGGGAGAGTTTCAGATCGAATGGAGATCTGCAGAGGGGGGGTCACAGTCAGCGTATGATGCTTACGCCGCAGCGCTTAACGCAGGCAGTAAGTCAGAGGCTCTTAGAGTAA
Protein Sequence MKMGNLIFTCSSSSKENTSAKITDSSTWYPQPGQHISIRTFRELNQAQTSSPIWRRTETPSTGESFRSNGDLQRGGHSQRMMLTPQRLTQAVSQRLLE

References More References in PubMed

1

Nano-PCR for the early detection of tomato leaf curl virus.

Devika PP, et al.  3 Biotech. 2024 Jan;14(1):5. doi: 10.1007/s13205-023-03842-2. Epub 2023 Dec 6.

PMID: 38074290
2

Association of chili leaf curl Vellanad virus with tomato leaf curl Joydebpur betasatellite in chili from Kerala, India.

Nizar I, et al.  Virusdisease. 2026 Mar;37(1):87-93. doi: 10.1007/s13337-026-00954-0. Epub 2026 Mar 7.

PMID: 42021941
3

Molecular characterization and infectivity analysis of tomato leaf curl New Delhi virus isolates infecting potato.

Jeevalatha A, et al.  3 Biotech. 2021 Apr;11(4):203. doi: 10.1007/s13205-021-02752-5. Epub 2021 Mar 30.

PMID: 33927993
4

Rapid detection of tomato leaf curl Bengaluru virus through loop mediated isothermal amplification assay.

Arutselvan R, et al.  Virusdisease. 2017 Sep;28(3):303-308. doi: 10.1007/s13337-017-0385-5. Epub 2017 Jun 13.

PMID: 29291217
5

RNA-seq analysis reveals an early defense response to tomato leaf curl New Delhi virus in potato cultivar Kufri Bahar.

Jeevalatha A, et al.  Funct Integr Genomics. 2023 Jun 30;23(3):215. doi: 10.1007/s10142-023-01138-5.

PMID: 37389664
6

Tomato leaf curl Kerala virus (ToLCKeV) AC3 protein forms a higher order oligomer and enhances ATPase activity of replication initiator protein (Rep/AC1).

Pasumarthy KK, et al.  Virol J. 2010 Jun 14;7:128. doi: 10.1186/1743-422X-7-128.

PMID: 20546567
7

The presence of tomato leaf curl Kerala virus AC3 protein enhances viral DNA replication and modulates virus induced gene-silencing mechanism in tomato plants.

Pasumarthy KK, et al.  Virol J. 2011 Apr 18;8:178. doi: 10.1186/1743-422X-8-178.

PMID: 21496351
8

Beneficial fungal root endophyte Piriformospora indica inhibits bitter gourd mosaic complex disease incited by combined infection of tomato leaf curl, papaya ringspot, and cucumber mosaic viruses without compromising crop growth and yield by orchestrating ROS production and scavenging through retrograde signaling.

Chandran DR, et al.  Front Microbiol. 2026 Mar 18;17:1781341. doi: 10.3389/fmicb.2026.1781341. eCollection 2026.

PMID: 41929680
9

A New Begomovirus Species in Association with Betasatellite Causing Tomato Leaf Curl Disease in Gandhinagar, India.

Rathore S, et al.  Plant Dis. 2014 Mar;98(3):428. doi: 10.1094/PDIS-07-13-0719-PDN.

PMID: 30708408
10

Recombinase polymerase amplification applied to plant virus detection and potential implications.

Babu B, et al.  Anal Biochem. 2018 Apr 1;546:72-77. doi: 10.1016/j.ab.2018.01.021. Epub 2018 Jan 31.

PMID: 29408177