Tobacco mottle leaf curl virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_002986925.1
Isolate Cuba:Sancti Spiritus
Release date 2018/8/26
Submitter Dominguez,M., Ramos,P.L., Sanchez,Y., Crespo,J., Andino,V., Pujol,M., Borroto,C., Milagros,D.M.
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_038893
ACCGGATGGCCGCGCGCTCCCCCAGGTGCCGTACTCTCGGGCGCGCAACGCTTTTCTTCGCATGCGCTGTCTTCCAATCATGTTGCGTCTGACGGGCCTAGATATTTTCAACAACTTGGTCGCTAAGTTGTTGCCCCGTCTATAAAGGAAAAGCGGGCTGGGCCAACGTCTTTAACTCAAAATGCCTAAGCGCGATCTCCCATGGCGCCCTTACGCGAAAATATCCAAGGTGAGCCGCAATGCGAATTACTCGCCCCGTACAAGAGTTGGCCCAATTGTCGACAAGGCCGCTGAATGGGTGAACAGGCCCATGTATAGGAAGCCCAGGATCTATCGGACGGTGAGAACCCCCGATGTGCCCAGGGGATGTGAAGGGCCTTGTAAGGTCCAGTCCTATGAACAGCGCCACGACATCTCGCACGTGGGCAAGGTCATGTGTATATCCGACGTGACACGTGGTAATGGCATTACCCATCGTGTTGGTAAGCGTTTTTGTGTTAAGTCTGTGTATATCCTAGGGAAGATCGGGAAAATTTGGATGGATGAGAACATCAAGCTCAAGAACCACACGAACAGCGTCATGTTCTGGTTGGTCAGGGACCGTAGACCGTATGGAACGCCGATGGATTTCGGTCAGGTGTTCAACATGTTCGACAACGAGCCCAGTACCGCTACGGTTAAGAACGATCTACGTGATCGTTACCAGGTCATGCATCGGTTCCATGCTAAGGTCACGGGTGGACAGTATGCCAGCAACGAGCAGGCGATTGTGAGGCGGTTTTGGAAGGTCAACAACCACGTGGTCTACAACCACCAGGAGGCTGGCAAGTACGAGAACCACACGGAGAACGCCCTGTTATTGTATATGGCATGTACTCATGCCTCTAATCCTGTATATGCAACTCTGAAGATACGAATCTATTTTTATGATTCGGTCATGAATTAATAAATTTTGAATTTTATTGAGTGATTTTCCAGTACATGATTTACATATGGTCTGTCTGTCGCGAAACGAACAGCTCTAATTACATTGTTAATGGAAATCACGCCTAATTGATCTAAGTACATGTTAACTAAGTGCCTAAACCTAAGCAAATATGTCGTTCCAGAAGCTGTCGTCGATGTCGTCCAGACTTGGAAGTTCAGGTAAGCCTTGTGGAGATCCAACGCTCTCCTGAGGTTGTGGTTGAACCGTATCTGGATGTGGTATATTCGTGTCCTGGTGTATGGAAGGTCCTCTACGTTGTATATCTTGAAATACAGGGGATTTTCTATCTCCCAGATATACGCGCCATTCTCCGCCTGATGTGCAGTGATGGGTTCCCCGGTGCGTGAATCCATGTCCCCGGCAGTCTATGTGGAAGTATATGGAGCACCCGCACTCTAGATCAATGCGTCTCCTCCTGATGGCCCTCCTCTCTGGCTTGCCTGTGTGCCTTCTTGATAGAGGGGGGCTGGAGGGGACGAGCCGCATCTGTCCCCAAAATTCCTGAGTGATGAGTTTTCCTCTTTGTCTAGGAAATCTTTATAGCTGGCACCCTCACCAGGATTGCATAGCACGATTGCTGGGATCCCGCCTTTAATTTGAACTGGCTTTCCGTATTTGCAGTTTGACTGCCAGTCTTTTTGTGACCCCAGCAATTCTTTCCAGTGCTTTAGCTTTAGATAGTGCGGTGCGACGTCATCAATTACGTTATACTCCACTTCGTTCGAGTAGACCCGGTGATTGAAGTCTAGGTGACCAGAGAGATAGTTATGTGGGCCTAACGCACGTGCCCACATTGTCTTACTGCAGGCCCACATTGTCTTCCCGGTCCTTGAATCACCTTCGACGATGATACTCATAGGTCTCTCCGGCCGCGCAGCGGAACCCCTTCCAAAATACTCATCGGCCCACTCTTGCATTTCTTCCGGGACGTTAGTGAGCGAGGAGAGTTGAAACGGAGGGACCCACGGTTCCGGAGCCTTTTGAAAGATCCTTTGTGCATTTGCGACGAGGTTATGATGTTGGAGGAAGAAATGTTGAGGCTGCTCTTCTTTTATTATTTGTAGAGCCTCTTCTGCAGAAGAGGCATTTAACGCCTTGGCATACGTGTCGTTAGCCGATTGGCAGCCTCCTCTAGCACTTCTTCCGTCGACCTGGAACTCTCCCCATTCCAGTGTATCTCCGTCCTTGTCGATGTAGGACTTGACGTCGGAGCTCGATTTAGCTCCCTGAACGTTCGGATGGAAATGTGCTGACCGAGATGGGGAGACCAAGTCGAAGAATCTGTAATTCGTGCAGACGTACTTGCCTTCGAATTGGACAAGCACGTGGAGATGAGGCTCCCCATTCTCATGAAGCTCTCTGCATATCTTGATGAACTTCTTGTTTACTGGTGTGTCTAGGTTTTGTAATTGGGAAAGTGCCTCCTCTTTGCTAAGAGAGCACTGTGGATAAGTGAGAAAATAATTTCTTGACTGAACTCTAAATTTCTTAACCGATGGCATTTTTGTAATAATAGGGGGGGTCTCCAATTGAGTTCTCTCAAAACTTGCTCATGCCAATTGGAGACCGGAGTACCTTATATACTAGAACCCTCAATAGAACTCTCAATCTCGTTCGCACACGTGGCGGCCATCCGCTATAATATT

Gene Information

NCBI Accession YP_009508169.1
Location 182-946
Gene Name AV1
Protein Name coat protein
Coding Region ATGCCTAAGCGCGATCTCCCATGGCGCCCTTACGCGAAAATATCCAAGGTGAGCCGCAATGCGAATTACTCGCCCCGTACAAGAGTTGGCCCAATTGTCGACAAGGCCGCTGAATGGGTGAACAGGCCCATGTATAGGAAGCCCAGGATCTATCGGACGGTGAGAACCCCCGATGTGCCCAGGGGATGTGAAGGGCCTTGTAAGGTCCAGTCCTATGAACAGCGCCACGACATCTCGCACGTGGGCAAGGTCATGTGTATATCCGACGTGACACGTGGTAATGGCATTACCCATCGTGTTGGTAAGCGTTTTTGTGTTAAGTCTGTGTATATCCTAGGGAAGATCGGGAAAATTTGGATGGATGAGAACATCAAGCTCAAGAACCACACGAACAGCGTCATGTTCTGGTTGGTCAGGGACCGTAGACCGTATGGAACGCCGATGGATTTCGGTCAGGTGTTCAACATGTTCGACAACGAGCCCAGTACCGCTACGGTTAAGAACGATCTACGTGATCGTTACCAGGTCATGCATCGGTTCCATGCTAAGGTCACGGGTGGACAGTATGCCAGCAACGAGCAGGCGATTGTGAGGCGGTTTTGGAAGGTCAACAACCACGTGGTCTACAACCACCAGGAGGCTGGCAAGTACGAGAACCACACGGAGAACGCCCTGTTATTGTATATGGCATGTACTCATGCCTCTAATCCTGTATATGCAACTCTGAAGATACGAATCTATTTTTATGATTCGGTCATGAATTAA
Protein Sequence MPKRDLPWRPYAKISKVSRNANYSPRTRVGPIVDKAAEWVNRPMYRKPRIYRTVRTPDVPRGCEGPCKVQSYEQRHDISHVGKVMCISDVTRGNGITHRVGKRFCVKSVYILGKIGKIWMDENIKLKNHTNSVMFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATVKNDLRDRYQVMHRFHAKVTGGQYASNEQAIVRRFWKVNNHVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSVMN

NCBI Accession YP_009508170.1
Location 943-1341
Gene Name AC3
Protein Name replication enhancement protein
Coding Region ATGGATTCACGCACCGGGGAACCCATCACTGCACATCAGGCGGAGAATGGCGCGTATATCTGGGAGATAGAAAATCCCCTGTATTTCAAGATATACAACGTAGAGGACCTTCCATACACCAGGACACGAATATACCACATCCAGATACGGTTCAACCACAACCTCAGGAGAGCGTTGGATCTCCACAAGGCTTACCTGAACTTCCAAGTCTGGACGACATCGACGACAGCTTCTGGAACGACATATTTGCTTAGGTTTAGGCACTTAGTTAACATGTACTTAGATCAATTAGGCGTGATTTCCATTAACAATGTAATTAGAGCTGTTCGTTTCGCGACAGACAGACCATATGTAAATCATGTACTGGAAAATCACTCAATAAAATTCAAAATTTATTAA
Protein Sequence MDSRTGEPITAHQAENGAYIWEIENPLYFKIYNVEDLPYTRTRIYHIQIRFNHNLRRALDLHKAYLNFQVWTTSTTASGTTYLLRFRHLVNMYLDQLGVISINNVIRAVRFATDRPYVNHVLENHSIKFKIY

NCBI Accession YP_009508171.1
Location 1088-1474
Gene Name AC2
Protein Name transactivator protein
Coding Region ATGCGGCTCGTCCCCTCCAGCCCCCCTCTATCAAGAAGGCACACAGGCAAGCCAGAGAGGAGGGCCATCAGGAGGAGACGCATTGATCTAGAGTGCGGGTGCTCCATATACTTCCACATAGACTGCCGGGGACATGGATTCACGCACCGGGGAACCCATCACTGCACATCAGGCGGAGAATGGCGCGTATATCTGGGAGATAGAAAATCCCCTGTATTTCAAGATATACAACGTAGAGGACCTTCCATACACCAGGACACGAATATACCACATCCAGATACGGTTCAACCACAACCTCAGGAGAGCGTTGGATCTCCACAAGGCTTACCTGAACTTCCAAGTCTGGACGACATCGACGACAGCTTCTGGAACGACATATTTGCTTAG
Protein Sequence MRLVPSSPPLSRRHTGKPERRAIRRRRIDLECGCSIYFHIDCRGHGFTHRGTHHCTSGGEWRVYLGDRKSPVFQDIQRRGPSIHQDTNIPHPDTVQPQPQESVGSPQGLPELPSLDDIDDSFWNDIFA

NCBI Accession YP_009508172.1
Location 1384-2490
Gene Name AC1
Protein Name replication associated protein
Coding Region ATGCCATCGGTTAAGAAATTTAGAGTTCAGTCAAGAAATTATTTTCTCACTTATCCACAGTGCTCTCTTAGCAAAGAGGAGGCACTTTCCCAATTACAAAACCTAGACACACCAGTAAACAAGAAGTTCATCAAGATATGCAGAGAGCTTCATGAGAATGGGGAGCCTCATCTCCACGTGCTTGTCCAATTCGAAGGCAAGTACGTCTGCACGAATTACAGATTCTTCGACTTGGTCTCCCCATCTCGGTCAGCACATTTCCATCCGAACGTTCAGGGAGCTAAATCGAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGATACACTGGAATGGGGAGAGTTCCAGGTCGACGGAAGAAGTGCTAGAGGAGGCTGCCAATCGGCTAACGACACGTATGCCAAGGCGTTAAATGCCTCTTCTGCAGAAGAGGCTCTACAAATAATAAAAGAAGAGCAGCCTCAACATTTCTTCCTCCAACATCATAACCTCGTCGCAAATGCACAAAGGATCTTTCAAAAGGCTCCGGAACCGTGGGTCCCTCCGTTTCAACTCTCCTCGCTCACTAACGTCCCGGAAGAAATGCAAGAGTGGGCCGATGAGTATTTTGGAAGGGGTTCCGCTGCGCGGCCGGAGAGACCTATGAGTATCATCGTCGAAGGTGATTCAAGGACCGGGAAGACAATGTGGGCCTGCAGTAAGACAATGTGGGCACGTGCGTTAGGCCCACATAACTATCTCTCTGGTCACCTAGACTTCAATCACCGGGTCTACTCGAACGAAGTGGAGTATAACGTAATTGATGACGTCGCACCGCACTATCTAAAGCTAAAGCACTGGAAAGAATTGCTGGGGTCACAAAAAGACTGGCAGTCAAACTGCAAATACGGAAAGCCAGTTCAAATTAAAGGCGGGATCCCAGCAATCGTGCTATGCAATCCTGGTGAGGGTGCCAGCTATAAAGATTTCCTAGACAAAGAGGAAAACTCATCACTCAGGAATTTTGGGGACAGATGCGGCTCGTCCCCTCCAGCCCCCCTCTATCAAGAAGGCACACAGGCAAGCCAGAGAGGAGGGCCATCAGGAGGAGACGCATTGATCTAG
Protein Sequence MPSVKKFRVQSRNYFLTYPQCSLSKEEALSQLQNLDTPVNKKFIKICRELHENGEPHLHVLVQFEGKYVCTNYRFFDLVSPSRSAHFHPNVQGAKSSSDVKSYIDKDGDTLEWGEFQVDGRSARGGCQSANDTYAKALNASSAEEALQIIKEEQPQHFFLQHHNLVANAQRIFQKAPEPWVPPFQLSSLTNVPEEMQEWADEYFGRGSAARPERPMSIIVEGDSRTGKTMWACSKTMWARALGPHNYLSGHLDFNHRVYSNEVEYNVIDDVAPHYLKLKHWKELLGSQKDWQSNCKYGKPVQIKGGIPAIVLCNPGEGASYKDFLDKEENSSLRNFGDRCGSSPPAPLYQEGTQASQRGGPSGGDALI

NCBI Accession YP_009508173.1
Location 2076-2339
Gene Name AC4
Protein Name AC4 protein
Coding Region ATGAGAATGGGGAGCCTCATCTCCACGTGCTTGTCCAATTCGAAGGCAAGTACGTCTGCACGAATTACAGATTCTTCGACTTGGTCTCCCCATCTCGGTCAGCACATTTCCATCCGAACGTTCAGGGAGCTAAATCGAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGATACACTGGAATGGGGAGAGTTCCAGGTCGACGGAAGAAGTGCTAGAGGAGGCTGCCAATCGGCTAACGACACGTATGCCAAGGCGTTAA
Protein Sequence MRMGSLISTCLSNSKASTSARITDSSTWSPHLGQHISIRTFRELNRAPTSSPTSTRTEIHWNGESSRSTEEVLEEAANRLTTRMPRR

References More References in PubMed

1

Occurrence of Sweet potato feathery mottle virus and Sweet potato leaf curl Georgia virus on Sweet Potato in India.

Prasanth G, et al.  Plant Dis. 2008 Feb;92(2):311. doi: 10.1094/PDIS-92-2-0311B.

PMID: 30769415
2

Evidence of local evolution of tomato-infecting begomovirus species in West Africa: characterization of tomato leaf curl Mali virus and tomato yellow leaf crumple virus from Mali.

Zhou YC, et al.  Arch Virol. 2008;153(4):693-706. doi: 10.1007/s00705-008-0042-9. Epub 2008 Feb 16.

PMID: 18278427
3

Pest categorisation of non-EU viruses of Rubus L.

EFSA Panel on Plant Health (PLH), et al.  EFSA J. 2020 Jan 16;18(1):e05928. doi: 10.2903/j.efsa.2020.5928. eCollection 2020 Jan.

PMID: 32626483
4

Predominance of tomato leaf curl Gujarat virus as a monopartite begomovirus: association with tomato yellow leaf curl Thailand betasatellite.

Jyothsna P, et al.  Arch Virol. 2013 Jan;158(1):217-24. doi: 10.1007/s00705-012-1468-7. Epub 2012 Sep 15.

PMID: 22983111
5

Potential risk of plant viruses entering disease cycle in surface water in protected vegetable growing areas of Eastern China.

Zhang X, et al.  PLoS One. 2023 Jan 25;18(1):e0280303. doi: 10.1371/journal.pone.0280303. eCollection 2023.

PMID: 36696381
6

RNA viruses and their silencing suppressors boost Abutilon mosaic virus, but not the Old World Tomato yellow leaf curl Sardinia virus.

Sardo L, et al.  Virus Res. 2011 Nov;161(2):170-80. doi: 10.1016/j.virusres.2011.07.021. Epub 2011 Aug 4.

PMID: 21843560
7

Molecular characterization of a new begomovirus infecting Mirabilis jalapa in northern India.

Kulshreshtha A, et al.  Arch Virol. 2017 Jul;162(7):2163-2167. doi: 10.1007/s00705-017-3330-4. Epub 2017 Mar 24.

PMID: 28342034
8

Characterization of a novel recombinant begomovirus and tomato leaf curl Kunene virus infecting bottle gourd in Kenya.

Ringeera KH, et al.  Mol Biol Rep. 2025 Sep 13;52(1):901. doi: 10.1007/s11033-025-11020-1.

PMID: 40944776
9

Heterologous expression of pepper mild mottle virus coat protein encoding region and its application in immuno-diagnostics.

Kumari N, et al.  Virusdisease. 2020 Sep;31(3):323-332. doi: 10.1007/s13337-020-00597-9. Epub 2020 May 15.

PMID: 32904916
10

The invasion biology of tomato begomoviruses in Costa Rica reveals neutral synergism that may lead to increased disease pressure and economic loss.

Maliano MR, et al.  Virus Res. 2022 Aug;317:198793. doi: 10.1016/j.virusres.2022.198793. Epub 2022 May 13.

PMID: 35569691