Tobacco mottle leaf curl virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_002986925.1
Isolate Cuba:Sancti Spiritus
Release date 2018/8/26
Submitter Dominguez,M., Ramos,P.L., Sanchez,Y., Crespo,J., Andino,V., Pujol,M., Borroto,C., Milagros,D.M.
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_038893
ACCGGATGGCCGCGCGCTCCCCCAGGTGCCGTACTCTCGGGCGCGCAACGCTTTTCTTCGCATGCGCTGTCTTCCAATCATGTTGCGTCTGACGGGCCTAGATATTTTCAACAACTTGGTCGCTAAGTTGTTGCCCCGTCTATAAAGGAAAAGCGGGCTGGGCCAACGTCTTTAACTCAAAATGCCTAAGCGCGATCTCCCATGGCGCCCTTACGCGAAAATATCCAAGGTGAGCCGCAATGCGAATTACTCGCCCCGTACAAGAGTTGGCCCAATTGTCGACAAGGCCGCTGAATGGGTGAACAGGCCCATGTATAGGAAGCCCAGGATCTATCGGACGGTGAGAACCCCCGATGTGCCCAGGGGATGTGAAGGGCCTTGTAAGGTCCAGTCCTATGAACAGCGCCACGACATCTCGCACGTGGGCAAGGTCATGTGTATATCCGACGTGACACGTGGTAATGGCATTACCCATCGTGTTGGTAAGCGTTTTTGTGTTAAGTCTGTGTATATCCTAGGGAAGATCGGGAAAATTTGGATGGATGAGAACATCAAGCTCAAGAACCACACGAACAGCGTCATGTTCTGGTTGGTCAGGGACCGTAGACCGTATGGAACGCCGATGGATTTCGGTCAGGTGTTCAACATGTTCGACAACGAGCCCAGTACCGCTACGGTTAAGAACGATCTACGTGATCGTTACCAGGTCATGCATCGGTTCCATGCTAAGGTCACGGGTGGACAGTATGCCAGCAACGAGCAGGCGATTGTGAGGCGGTTTTGGAAGGTCAACAACCACGTGGTCTACAACCACCAGGAGGCTGGCAAGTACGAGAACCACACGGAGAACGCCCTGTTATTGTATATGGCATGTACTCATGCCTCTAATCCTGTATATGCAACTCTGAAGATACGAATCTATTTTTATGATTCGGTCATGAATTAATAAATTTTGAATTTTATTGAGTGATTTTCCAGTACATGATTTACATATGGTCTGTCTGTCGCGAAACGAACAGCTCTAATTACATTGTTAATGGAAATCACGCCTAATTGATCTAAGTACATGTTAACTAAGTGCCTAAACCTAAGCAAATATGTCGTTCCAGAAGCTGTCGTCGATGTCGTCCAGACTTGGAAGTTCAGGTAAGCCTTGTGGAGATCCAACGCTCTCCTGAGGTTGTGGTTGAACCGTATCTGGATGTGGTATATTCGTGTCCTGGTGTATGGAAGGTCCTCTACGTTGTATATCTTGAAATACAGGGGATTTTCTATCTCCCAGATATACGCGCCATTCTCCGCCTGATGTGCAGTGATGGGTTCCCCGGTGCGTGAATCCATGTCCCCGGCAGTCTATGTGGAAGTATATGGAGCACCCGCACTCTAGATCAATGCGTCTCCTCCTGATGGCCCTCCTCTCTGGCTTGCCTGTGTGCCTTCTTGATAGAGGGGGGCTGGAGGGGACGAGCCGCATCTGTCCCCAAAATTCCTGAGTGATGAGTTTTCCTCTTTGTCTAGGAAATCTTTATAGCTGGCACCCTCACCAGGATTGCATAGCACGATTGCTGGGATCCCGCCTTTAATTTGAACTGGCTTTCCGTATTTGCAGTTTGACTGCCAGTCTTTTTGTGACCCCAGCAATTCTTTCCAGTGCTTTAGCTTTAGATAGTGCGGTGCGACGTCATCAATTACGTTATACTCCACTTCGTTCGAGTAGACCCGGTGATTGAAGTCTAGGTGACCAGAGAGATAGTTATGTGGGCCTAACGCACGTGCCCACATTGTCTTACTGCAGGCCCACATTGTCTTCCCGGTCCTTGAATCACCTTCGACGATGATACTCATAGGTCTCTCCGGCCGCGCAGCGGAACCCCTTCCAAAATACTCATCGGCCCACTCTTGCATTTCTTCCGGGACGTTAGTGAGCGAGGAGAGTTGAAACGGAGGGACCCACGGTTCCGGAGCCTTTTGAAAGATCCTTTGTGCATTTGCGACGAGGTTATGATGTTGGAGGAAGAAATGTTGAGGCTGCTCTTCTTTTATTATTTGTAGAGCCTCTTCTGCAGAAGAGGCATTTAACGCCTTGGCATACGTGTCGTTAGCCGATTGGCAGCCTCCTCTAGCACTTCTTCCGTCGACCTGGAACTCTCCCCATTCCAGTGTATCTCCGTCCTTGTCGATGTAGGACTTGACGTCGGAGCTCGATTTAGCTCCCTGAACGTTCGGATGGAAATGTGCTGACCGAGATGGGGAGACCAAGTCGAAGAATCTGTAATTCGTGCAGACGTACTTGCCTTCGAATTGGACAAGCACGTGGAGATGAGGCTCCCCATTCTCATGAAGCTCTCTGCATATCTTGATGAACTTCTTGTTTACTGGTGTGTCTAGGTTTTGTAATTGGGAAAGTGCCTCCTCTTTGCTAAGAGAGCACTGTGGATAAGTGAGAAAATAATTTCTTGACTGAACTCTAAATTTCTTAACCGATGGCATTTTTGTAATAATAGGGGGGGTCTCCAATTGAGTTCTCTCAAAACTTGCTCATGCCAATTGGAGACCGGAGTACCTTATATACTAGAACCCTCAATAGAACTCTCAATCTCGTTCGCACACGTGGCGGCCATCCGCTATAATATT

Gene Information

NCBI Accession YP_009508169.1
Location 182-946
Gene Name AV1
Protein Name coat protein
Coding Region ATGCCTAAGCGCGATCTCCCATGGCGCCCTTACGCGAAAATATCCAAGGTGAGCCGCAATGCGAATTACTCGCCCCGTACAAGAGTTGGCCCAATTGTCGACAAGGCCGCTGAATGGGTGAACAGGCCCATGTATAGGAAGCCCAGGATCTATCGGACGGTGAGAACCCCCGATGTGCCCAGGGGATGTGAAGGGCCTTGTAAGGTCCAGTCCTATGAACAGCGCCACGACATCTCGCACGTGGGCAAGGTCATGTGTATATCCGACGTGACACGTGGTAATGGCATTACCCATCGTGTTGGTAAGCGTTTTTGTGTTAAGTCTGTGTATATCCTAGGGAAGATCGGGAAAATTTGGATGGATGAGAACATCAAGCTCAAGAACCACACGAACAGCGTCATGTTCTGGTTGGTCAGGGACCGTAGACCGTATGGAACGCCGATGGATTTCGGTCAGGTGTTCAACATGTTCGACAACGAGCCCAGTACCGCTACGGTTAAGAACGATCTACGTGATCGTTACCAGGTCATGCATCGGTTCCATGCTAAGGTCACGGGTGGACAGTATGCCAGCAACGAGCAGGCGATTGTGAGGCGGTTTTGGAAGGTCAACAACCACGTGGTCTACAACCACCAGGAGGCTGGCAAGTACGAGAACCACACGGAGAACGCCCTGTTATTGTATATGGCATGTACTCATGCCTCTAATCCTGTATATGCAACTCTGAAGATACGAATCTATTTTTATGATTCGGTCATGAATTAA
Protein Sequence MPKRDLPWRPYAKISKVSRNANYSPRTRVGPIVDKAAEWVNRPMYRKPRIYRTVRTPDVPRGCEGPCKVQSYEQRHDISHVGKVMCISDVTRGNGITHRVGKRFCVKSVYILGKIGKIWMDENIKLKNHTNSVMFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATVKNDLRDRYQVMHRFHAKVTGGQYASNEQAIVRRFWKVNNHVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSVMN

NCBI Accession YP_009508170.1
Location 943-1341
Gene Name AC3
Protein Name replication enhancement protein
Coding Region ATGGATTCACGCACCGGGGAACCCATCACTGCACATCAGGCGGAGAATGGCGCGTATATCTGGGAGATAGAAAATCCCCTGTATTTCAAGATATACAACGTAGAGGACCTTCCATACACCAGGACACGAATATACCACATCCAGATACGGTTCAACCACAACCTCAGGAGAGCGTTGGATCTCCACAAGGCTTACCTGAACTTCCAAGTCTGGACGACATCGACGACAGCTTCTGGAACGACATATTTGCTTAGGTTTAGGCACTTAGTTAACATGTACTTAGATCAATTAGGCGTGATTTCCATTAACAATGTAATTAGAGCTGTTCGTTTCGCGACAGACAGACCATATGTAAATCATGTACTGGAAAATCACTCAATAAAATTCAAAATTTATTAA
Protein Sequence MDSRTGEPITAHQAENGAYIWEIENPLYFKIYNVEDLPYTRTRIYHIQIRFNHNLRRALDLHKAYLNFQVWTTSTTASGTTYLLRFRHLVNMYLDQLGVISINNVIRAVRFATDRPYVNHVLENHSIKFKIY

NCBI Accession YP_009508171.1
Location 1088-1474
Gene Name AC2
Protein Name transactivator protein
Coding Region ATGCGGCTCGTCCCCTCCAGCCCCCCTCTATCAAGAAGGCACACAGGCAAGCCAGAGAGGAGGGCCATCAGGAGGAGACGCATTGATCTAGAGTGCGGGTGCTCCATATACTTCCACATAGACTGCCGGGGACATGGATTCACGCACCGGGGAACCCATCACTGCACATCAGGCGGAGAATGGCGCGTATATCTGGGAGATAGAAAATCCCCTGTATTTCAAGATATACAACGTAGAGGACCTTCCATACACCAGGACACGAATATACCACATCCAGATACGGTTCAACCACAACCTCAGGAGAGCGTTGGATCTCCACAAGGCTTACCTGAACTTCCAAGTCTGGACGACATCGACGACAGCTTCTGGAACGACATATTTGCTTAG
Protein Sequence MRLVPSSPPLSRRHTGKPERRAIRRRRIDLECGCSIYFHIDCRGHGFTHRGTHHCTSGGEWRVYLGDRKSPVFQDIQRRGPSIHQDTNIPHPDTVQPQPQESVGSPQGLPELPSLDDIDDSFWNDIFA

NCBI Accession YP_009508172.1
Location 1384-2490
Gene Name AC1
Protein Name replication associated protein
Coding Region ATGCCATCGGTTAAGAAATTTAGAGTTCAGTCAAGAAATTATTTTCTCACTTATCCACAGTGCTCTCTTAGCAAAGAGGAGGCACTTTCCCAATTACAAAACCTAGACACACCAGTAAACAAGAAGTTCATCAAGATATGCAGAGAGCTTCATGAGAATGGGGAGCCTCATCTCCACGTGCTTGTCCAATTCGAAGGCAAGTACGTCTGCACGAATTACAGATTCTTCGACTTGGTCTCCCCATCTCGGTCAGCACATTTCCATCCGAACGTTCAGGGAGCTAAATCGAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGATACACTGGAATGGGGAGAGTTCCAGGTCGACGGAAGAAGTGCTAGAGGAGGCTGCCAATCGGCTAACGACACGTATGCCAAGGCGTTAAATGCCTCTTCTGCAGAAGAGGCTCTACAAATAATAAAAGAAGAGCAGCCTCAACATTTCTTCCTCCAACATCATAACCTCGTCGCAAATGCACAAAGGATCTTTCAAAAGGCTCCGGAACCGTGGGTCCCTCCGTTTCAACTCTCCTCGCTCACTAACGTCCCGGAAGAAATGCAAGAGTGGGCCGATGAGTATTTTGGAAGGGGTTCCGCTGCGCGGCCGGAGAGACCTATGAGTATCATCGTCGAAGGTGATTCAAGGACCGGGAAGACAATGTGGGCCTGCAGTAAGACAATGTGGGCACGTGCGTTAGGCCCACATAACTATCTCTCTGGTCACCTAGACTTCAATCACCGGGTCTACTCGAACGAAGTGGAGTATAACGTAATTGATGACGTCGCACCGCACTATCTAAAGCTAAAGCACTGGAAAGAATTGCTGGGGTCACAAAAAGACTGGCAGTCAAACTGCAAATACGGAAAGCCAGTTCAAATTAAAGGCGGGATCCCAGCAATCGTGCTATGCAATCCTGGTGAGGGTGCCAGCTATAAAGATTTCCTAGACAAAGAGGAAAACTCATCACTCAGGAATTTTGGGGACAGATGCGGCTCGTCCCCTCCAGCCCCCCTCTATCAAGAAGGCACACAGGCAAGCCAGAGAGGAGGGCCATCAGGAGGAGACGCATTGATCTAG
Protein Sequence MPSVKKFRVQSRNYFLTYPQCSLSKEEALSQLQNLDTPVNKKFIKICRELHENGEPHLHVLVQFEGKYVCTNYRFFDLVSPSRSAHFHPNVQGAKSSSDVKSYIDKDGDTLEWGEFQVDGRSARGGCQSANDTYAKALNASSAEEALQIIKEEQPQHFFLQHHNLVANAQRIFQKAPEPWVPPFQLSSLTNVPEEMQEWADEYFGRGSAARPERPMSIIVEGDSRTGKTMWACSKTMWARALGPHNYLSGHLDFNHRVYSNEVEYNVIDDVAPHYLKLKHWKELLGSQKDWQSNCKYGKPVQIKGGIPAIVLCNPGEGASYKDFLDKEENSSLRNFGDRCGSSPPAPLYQEGTQASQRGGPSGGDALI

NCBI Accession YP_009508173.1
Location 2076-2339
Gene Name AC4
Protein Name AC4 protein
Coding Region ATGAGAATGGGGAGCCTCATCTCCACGTGCTTGTCCAATTCGAAGGCAAGTACGTCTGCACGAATTACAGATTCTTCGACTTGGTCTCCCCATCTCGGTCAGCACATTTCCATCCGAACGTTCAGGGAGCTAAATCGAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGATACACTGGAATGGGGAGAGTTCCAGGTCGACGGAAGAAGTGCTAGAGGAGGCTGCCAATCGGCTAACGACACGTATGCCAAGGCGTTAA
Protein Sequence MRMGSLISTCLSNSKASTSARITDSSTWSPHLGQHISIRTFRELNRAPTSSPTSTRTEIHWNGESSRSTEEVLEEAANRLTTRMPRR

References More References in PubMed

1

Pest categorisation of non-EU viruses of Rubus L.

EFSA Panel on Plant Health (PLH), et al.  EFSA J. 2020 Jan 16;18(1):e05928. doi: 10.2903/j.efsa.2020.5928. eCollection 2020 Jan.

PMID: 32626483
2

Evidence of local evolution of tomato-infecting begomovirus species in West Africa: characterization of tomato leaf curl Mali virus and tomato yellow leaf crumple virus from Mali.

Zhou YC, et al.  Arch Virol. 2008;153(4):693-706. doi: 10.1007/s00705-008-0042-9. Epub 2008 Feb 16.

PMID: 18278427
3

Predominance of tomato leaf curl Gujarat virus as a monopartite begomovirus: association with tomato yellow leaf curl Thailand betasatellite.

Jyothsna P, et al.  Arch Virol. 2013 Jan;158(1):217-24. doi: 10.1007/s00705-012-1468-7. Epub 2012 Sep 15.

PMID: 22983111
4

Heterologous expression of pepper mild mottle virus coat protein encoding region and its application in immuno-diagnostics.

Kumari N, et al.  Virusdisease. 2020 Sep;31(3):323-332. doi: 10.1007/s13337-020-00597-9. Epub 2020 May 15.

PMID: 32904916
5

RNA viruses and their silencing suppressors boost Abutilon mosaic virus, but not the Old World Tomato yellow leaf curl Sardinia virus.

Sardo L, et al.  Virus Res. 2011 Nov;161(2):170-80. doi: 10.1016/j.virusres.2011.07.021. Epub 2011 Aug 4.

PMID: 21843560
6

A New Begomovirus Causes Tomato Leaf Curl Disease in Baja California Sur, Mexico.

Holguín-Peña RJ, et al.  Plant Dis. 2005 Mar;89(3):341. doi: 10.1094/PD-89-0341A.

PMID: 30795368
7

Molecular characterization of a new begomovirus infecting Mirabilis jalapa in northern India.

Kulshreshtha A, et al.  Arch Virol. 2017 Jul;162(7):2163-2167. doi: 10.1007/s00705-017-3330-4. Epub 2017 Mar 24.

PMID: 28342034
8

Potential risk of plant viruses entering disease cycle in surface water in protected vegetable growing areas of Eastern China.

Zhang X, et al.  PLoS One. 2023 Jan 25;18(1):e0280303. doi: 10.1371/journal.pone.0280303. eCollection 2023.

PMID: 36696381
9

Occurrence and distribution of pepper veinal mottle virus and cucumber mosaic virus in pepper in Ibadan, Nigeria.

Arogundade O, et al.  Virol J. 2012 Apr 11;9:79. doi: 10.1186/1743-422X-9-79.

PMID: 22495040
10

First Report of a Begomovirus Associated with Tomato Yellow Leaf Curl Disease in Ethiopia.

Shih SL, et al.  Plant Dis. 2006 Jul;90(7):974. doi: 10.1094/PD-90-0974A.

PMID: 30781051