Tobacco leaf curl Yunnan virus

Basic Information

Genus Begomovirus
NCBI Assembly GCF_000860165.1
Isolate China:Yunnan
Release date 2015/2/13
Submitter Zhou,X.P., Xie,Y., Zhang,Z.K., Zhou,X.
Host
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

NC_004356
ACCTGTGGGCCGCGATTTTTTTTAAAGTGGGCCCGTTGATGTGATATGTCATCCAATCAGAACGCTCCCCCAAAGCTTAATTGTTTTGTGGTCCCTTATTTAAACTTGCTCACCAAGTAGTGCACTCCGCACTATGTGGGATCCATTATTAAACGAGTTTCCCGAAACCGTTCACGGCTTTAGGTGTATGTTAGCAGTTAAATATCTGCAGTTAGTAGAGAAGACTTATTCGCCTGATACATTAGGGCACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGAAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGCACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAGATCATGGACGAACAGGCCCATGAACAGAAAGCCCAAGATGTACAGGATGTACAGAAGTCCAGATGTCCCTAGAGGATGTGAAGGCCCATGTAAGGTTCAATCTTTTGATGCTAAGAACGATATTGGTCACATGGGCAAGGTCTTATGTTTGTCCGACGTTACCCGTGGTATTGGGCTTACCCATCGAGTTGGCAAGCGTTTCTGTGTCAAATCACTTTATTTTGTTGGCAAGATCTGGATGGATGAAAATATTAAGGTTAAGAACCACACTAACACCGTTTTATTCTGGATAGTTAGAGATCGGCGTCCTACTGGAACGCCTAATGATTTTCAGCAGGTCTTTAATGTATATGATAATGAACCTAGCACTGCTACTGTGAAGAACGATCAGCGTGATCGTTTTCAGGTTATAAGGAGGTTCCAGGCAACGGTGACTGGTGGACAATATGCAGCGAAGGAGCAGGCGATTATTAGAAAGTTTTATCGTGTTAATAATTATGTAGTTTACAATCATCAGGAAGCTGGCAAGTATGAGAACCATACCGAAAATGCTTTGTTGTTGTATATGGCATGTACTCATGCCTCTAATCCTGTGTATGCTACTTTGAAAGTCAGGAGTTATTTTTATGACTCAGTGACGAATTAATAAAGATTGAATTTTATTATATTAGAATTTGTTACATATTCTGTTTTTTCCAATACATCCCATAATACATGATTACATGCTCTAATTACATTGTTAATACTAATTACACCCAAATTATCTAAATATTTCATACATTGAACCTTAAATACTCTTAAGAAACGCCAAGTCTGAGGTTGTAAGCGAGTCCAGATCTGGAAGCTCAGAAAACACTGGTGTATTCCCAACGCTTTCCTCAGGTTGTGGTTGAACTGTATTTGGATCTGTATGATGTCGTGTTTGGTGTTGAATGGTCTCTCGTGGTGCTTGGTTATCTTGAAATAGAGGGGATTTCTGATCGTCCAGGTATACACGCCACTCTCGCATTGAGTTGCAGTGAGTAATTCCCCTGTGCGAAAATCCATGATTTGCACAATTTATGCCGAAGTAGTATGAGCACCCACACGTTAGATCAACTCTCCGCCTGCGAACTGGCCTCCTCTTGGCTATTCTGTGTTGCACTTTGATTGGTACCTGAGTACAATGGGCTGTTGAGGGTGATGAATTCCGCATTCTTTAATGCCCACTCTTTTAAAGCTGAATTCTTTTCTTCCTCCAAGAATTCTTTATATGATGATGTTGGGCCTGGATTGCAAAGGAAGATAGTTGGGATTCCACCTTTAATTTGAATTGGTTTCCCGTACTTGGTGTTGCTTTGCCAGTCCCTTTGGGCCCCCATGAATTCTTTAAAGTGCTTTAGATAGTGGGGGTCTACGTCATCAATGACGTTATACCAAGCATCATTACTGTACACCTTTGGACTCAGATCCAGATGACCGCACAGATAATTATGTGGGCCCAATGAACGCGCCCACATGGTTTTTCCTGTACGACTCTCTCCCTCTATGACAATACTGATGGGTCTCCATGGCCGCGCACCGGCATGCCTTACATTATCAGCAGCCCCATTCTTCAAGTTCTTTGGGAACTTGATCCAAATGATGAAAGATAAAAAAGGAGAACCAAAAACCTCTAAAGGAGGTGCAAAAATCCTATCTAAATTAGCATTTAAATTATGAAATTGTAAAACAAAATCTTTAGGAGCTAACTCCTTAATTACATTAAGAGCCTCTGACTTACTGCCGCTGTTAAGTGCCTGGGCGTAAGCGTCATTGGCTGTCTGTTGACCCCCTCTTGCAGATCTTCCGTCGATCTGAAACTCTCCCCATTCGAGGGTGTCTCCGTCCTTGTCGATGTAGGACTTGACGTCGGAGCTGGATTTAGCTCCCTGAATGTTCGGATGGAAATGTGCTGACCTGGTTGGGGATACCAAGTCGAAGAATCTGTTATTCGTGCAGACGTATTTCCCTTCGAACTGGATAAGCACGTGGAGATGAGGGCTCCCATCTTCGTGAAGCTCTCTGCAGATTTTGATATATTTTTTATTAGTTGGTGTCTCTAGGGCTTGTAATTGGGAAAGTGCTTCTTCTTTGTTGAGAGAGCACTGTGGATAAGTGAGGAAATAATTTTTGGCTTGTATTTTAAAACGTTTGGGAGGAGCCATTGACTTGGTCAATTGGAGACATTCATAGTTCTCTGTCAATTGGAGACAGGAGACAATATATAGGTGTCTCCAAATGGCATAGTGGTAATTTCTCATAGAAATTCCACTTTAATTTGAAATCCAAAAGCGGCCATCCGTATAATATT

Gene Information

NCBI Accession NP_722552.1
Location 134-490
Gene Name AV2
Protein Name AV2 protein
Coding Region ATGTGGGATCCATTATTAAACGAGTTTCCCGAAACCGTTCACGGCTTTAGGTGTATGTTAGCAGTTAAATATCTGCAGTTAGTAGAGAAGACTTATTCGCCTGATACATTAGGGCACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGAAATTATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGCACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAGATCATGGACGAACAGGCCCATGAACAGAAAGCCCAAGATGTACAGGATGTACAGAAGTCCAGATGTCCCTAG
Protein Sequence MWDPLLNEFPETVHGFRCMLAVKYLQLVEKTYSPDTLGHDLIRDLISVIRARNYVEATSRYNHFHARFEGTPPSQLRQPICEPCCCPHCPRHQSKIMDEQAHEQKAQDVQDVQKSRCP

NCBI Accession NP_722553.1
Location 294-1064
Gene Name AV1
Protein Name coat protein
Coding Region ATGTCGAAGCGACCAGCAGATATAATCATTTCCACGCCCGCTTCGAAGGCACGCCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAGATCATGGACGAACAGGCCCATGAACAGAAAGCCCAAGATGTACAGGATGTACAGAAGTCCAGATGTCCCTAGAGGATGTGAAGGCCCATGTAAGGTTCAATCTTTTGATGCTAAGAACGATATTGGTCACATGGGCAAGGTCTTATGTTTGTCCGACGTTACCCGTGGTATTGGGCTTACCCATCGAGTTGGCAAGCGTTTCTGTGTCAAATCACTTTATTTTGTTGGCAAGATCTGGATGGATGAAAATATTAAGGTTAAGAACCACACTAACACCGTTTTATTCTGGATAGTTAGAGATCGGCGTCCTACTGGAACGCCTAATGATTTTCAGCAGGTCTTTAATGTATATGATAATGAACCTAGCACTGCTACTGTGAAGAACGATCAGCGTGATCGTTTTCAGGTTATAAGGAGGTTCCAGGCAACGGTGACTGGTGGACAATATGCAGCGAAGGAGCAGGCGATTATTAGAAAGTTTTATCGTGTTAATAATTATGTAGTTTACAATCATCAGGAAGCTGGCAAGTATGAGAACCATACCGAAAATGCTTTGTTGTTGTATATGGCATGTACTCATGCCTCTAATCCTGTGTATGCTACTTTGAAAGTCAGGAGTTATTTTTATGACTCAGTGACGAATTAA
Protein Sequence MSKRPADIIISTPASKARRRLNFDSPYVSRAAAPIVRVTKARSWTNRPMNRKPKMYRMYRSPDVPRGCEGPCKVQSFDAKNDIGHMGKVLCLSDVTRGIGLTHRVGKRFCVKSLYFVGKIWMDENIKVKNHTNTVLFWIVRDRRPTGTPNDFQQVFNVYDNEPSTATVKNDQRDRFQVIRRFQATVTGGQYAAKEQAIIRKFYRVNNYVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKVRSYFYDSVTN

NCBI Accession NP_722554.1
Location 1061-1465
Gene Name AC3
Protein Name AC3 protein
Coding Region ATGGATTTTCGCACAGGGGAATTACTCACTGCAACTCAATGCGAGAGTGGCGTGTATACCTGGACGATCAGAAATCCCCTCTATTTCAAGATAACCAAGCACCACGAGAGACCATTCAACACCAAACACGACATCATACAGATCCAAATACAGTTCAACCACAACCTGAGGAAAGCGTTGGGAATACACCAGTGTTTTCTGAGCTTCCAGATCTGGACTCGCTTACAACCTCAGACTTGGCGTTTCTTAAGAGTATTTAAGGTTCAATGTATGAAATATTTAGATAATTTGGGTGTAATTAGTATTAACAATGTAATTAGAGCATGTAATCATGTATTATGGGATGTATTGGAAAAAACAGAATATGTAACAAATTCTAATATAATAAAATTCAATCTTTATTAA
Protein Sequence MDFRTGELLTATQCESGVYTWTIRNPLYFKITKHHERPFNTKHDIIQIQIQFNHNLRKALGIHQCFLSFQIWTRLQPQTWRFLRVFKVQCMKYLDNLGVISINNVIRACNHVLWDVLEKTEYVTNSNIIKFNLY

NCBI Accession NP_722555.1
Location 1206-1613
Gene Name AC2
Protein Name AC2 protein
Coding Region ATGCGGAATTCATCACCCTCAACAGCCCATTGTACTCAGGTACCAATCAAAGTGCAACACAGAATAGCCAAGAGGAGGCCAGTTCGCAGGCGGAGAGTTGATCTAACGTGTGGGTGCTCATACTACTTCGGCATAAATTGTGCAAATCATGGATTTTCGCACAGGGGAATTACTCACTGCAACTCAATGCGAGAGTGGCGTGTATACCTGGACGATCAGAAATCCCCTCTATTTCAAGATAACCAAGCACCACGAGAGACCATTCAACACCAAACACGACATCATACAGATCCAAATACAGTTCAACCACAACCTGAGGAAAGCGTTGGGAATACACCAGTGTTTTCTGAGCTTCCAGATCTGGACTCGCTTACAACCTCAGACTTGGCGTTTCTTAAGAGTATTTAA
Protein Sequence MRNSSPSTAHCTQVPIKVQHRIAKRRPVRRRRVDLTCGCSYYFGINCANHGFSHRGITHCNSMREWRVYLDDQKSPLFQDNQAPRETIQHQTRHHTDPNTVQPQPEESVGNTPVFSELPDLDSLTTSDLAFLKSI

NCBI Accession NP_722556.1
Location 1513-2604
Gene Name AC1
Protein Name Rep protein
Coding Region ATGGCTCCTCCCAAACGTTTTAAAATACAAGCCAAAAATTATTTCCTCACTTATCCACAGTGCTCTCTCAACAAAGAAGAAGCACTTTCCCAATTACAAGCCCTAGAGACACCAACTAATAAAAAATATATCAAAATCTGCAGAGAGCTTCACGAAGATGGGAGCCCTCATCTCCACGTGCTTATCCAGTTCGAAGGGAAATACGTCTGCACGAATAACAGATTCTTCGACTTGGTATCCCCAACCAGGTCAGCACATTTCCATCCGAACATTCAGGGAGCTAAATCCAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGACACCCTCGAATGGGGAGAGTTTCAGATCGACGGAAGATCTGCAAGAGGGGGTCAACAGACAGCCAATGACGCTTACGCCCAGGCACTTAACAGCGGCAGTAAGTCAGAGGCTCTTAATGTAATTAAGGAGTTAGCTCCTAAAGATTTTGTTTTACAATTTCATAATTTAAATGCTAATTTAGATAGGATTTTTGCACCTCCTTTAGAGGTTTTTGGTTCTCCTTTTTTATCTTTCATCATTTGGATCAAGTTCCCAAAGAACTTGAAGAATGGGGCTGCTGATAATGTAAGGCATGCCGGTGCGCGGCCATGGAGACCCATCAGTATTGTCATAGAGGGAGAGAGTCGTACAGGAAAAACCATGTGGGCGCGTTCATTGGGCCCACATAATTATCTGTGCGGTCATCTGGATCTGAGTCCAAAGGTGTACAGTAATGATGCTTGGTATAACGTCATTGATGACGTAGACCCCCACTATCTAAAGCACTTTAAAGAATTCATGGGGGCCCAAAGGGACTGGCAAAGCAACACCAAGTACGGGAAACCAATTCAAATTAAAGGTGGAATCCCAACTATCTTCCTTTGCAATCCAGGCCCAACATCATCATATAAAGAATTCTTGGAGGAAGAAAAGAATTCAGCTTTAAAAGAGTGGGCATTAAAGAATGCGGAATTCATCACCCTCAACAGCCCATTGTACTCAGGTACCAATCAAAGTGCAACACAGAATAGCCAAGAGGAGGCCAGTTCGCAGGCGGAGAGTTGA
Protein Sequence MAPPKRFKIQAKNYFLTYPQCSLNKEEALSQLQALETPTNKKYIKICRELHEDGSPHLHVLIQFEGKYVCTNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIDKDGDTLEWGEFQIDGRSARGGQQTANDAYAQALNSGSKSEALNVIKELAPKDFVLQFHNLNANLDRIFAPPLEVFGSPFLSFIIWIKFPKNLKNGAADNVRHAGARPWRPISIVIEGESRTGKTMWARSLGPHNYLCGHLDLSPKVYSNDAWYNVIDDVDPHYLKHFKEFMGAQRDWQSNTKYGKPIQIKGGIPTIFLCNPGPTSSYKEFLEEEKNSALKEWALKNAEFITLNSPLYSGTNQSATQNSQEEASSQAES

NCBI Accession NP_722557.1
Location 2157-2447
Gene Name AC4
Protein Name AC4 protein
Coding Region ATGGGAGCCCTCATCTCCACGTGCTTATCCAGTTCGAAGGGAAATACGTCTGCACGAATAACAGATTCTTCGACTTGGTATCCCCAACCAGGTCAGCACATTTCCATCCGAACATTCAGGGAGCTAAATCCAGCTCCGACGTCAAGTCCTACATCGACAAGGACGGAGACACCCTCGAATGGGGAGAGTTTCAGATCGACGGAAGATCTGCAAGAGGGGGTCAACAGACAGCCAATGACGCTTACGCCCAGGCACTTAACAGCGGCAGTAAGTCAGAGGCTCTTAATGTAA
Protein Sequence MGALISTCLSSSKGNTSARITDSSTWYPQPGQHISIRTFRELNPAPTSSPTSTRTETPSNGESFRSTEDLQEGVNRQPMTLTPRHLTAAVSQRLLM

References More References in PubMed

1

Distinct tomato yellow leaf curl Chuxiong virus isolated from whiteflies and plants in China and its symptom determinant and suppressor of post-transcriptional gene silencing.

Xie Y, et al.  Virology. 2024 Jun;594:110040. doi: 10.1016/j.virol.2024.110040. Epub 2024 Mar 5.

PMID: 38471198
2

Tomato leaf curl Yunnan virus-encoded C4 induces cell division through enhancing stability of Cyclin D 1.1 via impairing NbSKeta -mediated phosphorylation in Nicotiana benthamiana.

Mei Y, et al.  PLoS Pathog. 2018 Jan 2;14(1):e1006789. doi: 10.1371/journal.ppat.1006789. eCollection 2018 Jan.

PMID: 29293689
3

First Report of Ageratum yellow vein virus Causing Tobacco Leaf Curl Disease in Fujian Province, China.

Liu Z, et al.  Plant Dis. 2008 Jan;92(1):177. doi: 10.1094/PDIS-92-1-0177B.

PMID: 30786379
4

ty-5 Confers Broad-Spectrum Resistance to Geminiviruses.

Ren Y, et al.  Viruses. 2022 Aug 17;14(8):1804. doi: 10.3390/v14081804.

PMID: 36016426
5

Development and application of triple antibody sandwich enzyme-linked immunosorbent assays for begomovirus detection using monoclonal antibodies against Tomato yellow leaf curl Thailand virus.

Seepiban C, et al.  Virol J. 2017 May 30;14(1):99. doi: 10.1186/s12985-017-0763-z.

PMID: 28558726
6

The C4 protein encoded by tomato leaf curl Yunnan virus reverses transcriptional gene silencing by interacting with NbDRM2 and impairing its DNA-binding ability.

Mei Y, et al.  PLoS Pathog. 2020 Oct 1;16(10):e1008829. doi: 10.1371/journal.ppat.1008829. eCollection 2020 Oct.

PMID: 33002088
7

Incidence and Molecular Identification of Begomoviruses Infecting Tomato and Pepper in Myanmar.

Kwak HR, et al.  Plants (Basel). 2022 Apr 10;11(8):1031. doi: 10.3390/plants11081031.

PMID: 35448759
8

Divergent Symptoms Caused by Geminivirus-Encoded C4 Proteins Correlate with Their Ability To Bind NbSKη.

Mei Y, et al.  J Virol. 2020 Sep 29;94(20):e01307-20. doi: 10.1128/JVI.01307-20. Print 2020 Sep 29.

PMID: 32759325
9

Geminivirus C4 antagonizes the HIR1-mediated hypersensitive response by inhibiting the HIR1 self-interaction and promoting degradation of the protein.

Mei Y, et al.  New Phytol. 2020 Feb;225(3):1311-1326. doi: 10.1111/nph.16208. Epub 2019 Oct 29.

PMID: 31537050
10

A recombinant begomovirus resulting from exchange of the C4 gene.

Xie Y, et al.  J Gen Virol. 2013 Aug;94(Pt 8):1896-1907. doi: 10.1099/vir.0.053181-0. Epub 2013 May 29.

PMID: 23720217