Papaya severe leaf curl virus 2

Basic Information

Genus Begomovirus
Isolate India
Vector
Download Genome |GFF3 |PEP |CDS

Genomic Organization

JBrowse

Genome

MH988458
ACCGGATGGCCGCGATTTTTTTTTTGTGGCCCCAACAAAGCACTAACTGACAATGACAAGTTGACCAATGAGAATCGTTCCTCGTCGCCTAATTGTTTCGGGGTTCCCCCTATAAACTTAGTGCGCAAGTTGTGTTTTCCCTTCACTATGTGGGATCCATTGTTAAACGAGTTTCCCGAAACCGTTCACGGTTTTAGATGTATGTTAGCAGTTAAATATTTGCAGTTAGTAGAAAAGACTTATTCTCCCGATACATTAGGTTACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGGAACTATGGCGAAGCGACCAGCAGATATCATCATTTCAACGCCCGCATCGAAGGTACGTCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTCCGGGATGTACAGAAGTCCAGATGTCCCTAGGGGCTGGGAAGGTCCAGTTAAGGTCCAGTCCTTTGGATGCAGACATGATTTTGATCACATGGGTAAGGCCATTTGTCTTTGTGATGTTACTAGGGGTATTGGGCTGACCCATCGAGTAGCGAAGAGGTTTTGTGTGAAGTCTGTTTATGTGTTGGGTAAAATATGGATGGATGAAAATATAAAGACCAAGAATCACACGAACAATGTGATGTTCTTTCTCGTTCGTGACCGTAGACCAGTTGACAAGCCTCAGGATTTTGGTGAGGTTTTTAACATGTTTGATAATGAGCCCAGCACGGTGACGGTGAAAAATGTGCATCGGGATAGGTACCAGGTGCTCAGGAAGTGGCATGCAACTGTGACAGGGGGTCAATATGCATCGAAGGAGCAGGCTCTCGTGAAGAAGTTTATTAGGGTTAATAATTATGTTGTGTACAACCAACAAGAGGCTGGCAAATATGAGAATCATACTGAGAATGCGTTAATGTTGTATATGGCGTGTACGCACGCCTCTAATCCCGTGTATGCTACATTGAAGATACGGATCTACTTCTATGACTCTGTATCGAATTAATAAATATAGAATTTTATTGAAGATGATTGGTCTAAATATACATCATGTTCTGATACATCGTATAATACATGTTTAAAGGCCCTAACTACATTATTTATACTAATGACTCCTAGATTATCTAAATACTTTAAAACCTGACTCCTAAAGACTCTTAAGAAATGCCCGGTCTGAGGTTGTAAAGCCATGCAGATTCTTAAGCCCAAAAAACACTTCAGTATCCTCAGTTCCTTCCTGAGGTTGTGATTGAACTGGATCTGGAGAGTGATGATGTCGTGGTTCATGGAAAATGGCCTTTGGTCGTGGTCTGAGGACTTGAAATATAGGGGATTTGGGACCTTCCAGATATACACCCCATTCATTTCCTGAGCTGCAGTGATGAGTTCCCCTGTGCGTGAATCCATGATTGTGGCAGGCTGATGGTACGTAGTAAGAGCAACCACCCTCGAGATCAACACTTCGCCGGATGGTCCCCTGCTTGGCTAGCCTGTGTTGGACCTTGATTGGTACCTGAGTACAGTGGCTCTGTGAGGGTGATGAATTTTGCATTCTTTATAGCCCACGCTCTTAGTGCCGAATTCTTGTCCTCGTCCAAGAACTCTTTATAGCTGGAAGTGGACCCAGGATTGCAGAGGAAGATAGTGGGAATGCCCCCTTTAATTTGAACGGGCTTCCCGTACTTGGTGTTGCTTTGCCAGTCTCTTTGGGCCCCCATGAATTCTTTAAAGTGCTCTAGGTAGTGGGGATCGACGTCATCAATGACGTTGTACCAGGCCTCGTTGCTGTAGACCTTTGGACTAAGGTCTAAATGACCACACAGATAATTGTGTGGACCCAGTGACCTGGCCCACATCGTCTTCCCCGTTCTACTATCACCCTCTAAGACAATACTTTTAGATCTCAATGGCCGCGCAGCGGTACCCATCACATTTTCAGCAGCCCATTCCTCTATGGCCTCCGGCACCTGATCGAATGAACAACAAGAAATGGGGGAAACATAAACCTCCACTGGAGGTGTCCAAATCCTATCTAAATTATTTTTTAAATTATGATATTGAAAAATAAAATCTTCCGGGAGTTTCTCCCTAATAATTGCTAAAGCAGCTTCCGCTGAACCTGCATTTAGGGCCTCCGCTGCACCATCACTACCTGTCTGTTGACCTCCACTAGCAAATCGCCCACCGATCTGAAACTCACCCCAGTCGATGTACTCTCCGCCCTTCTGGATGTAGGACTTGACACCTGACCTGCACTTAGCTCCCTGAAACCCGGGGTGGAACTGGCTTGAGGTATTAGGGCGAGCGATTTCAAAATGTCTGTCTTCTCTGAACCGCAATTTCCCTTTGAATTGGATGAAACCCTGGATACGCAGAGACCAATCTTGGTGTTTTTCTTTTGATACTCTGATAAACAATTTATCAAGAGGACAGGTAATGTTTTTAAATAGTTCGAGCATTTGCTCTTTGCGTATTGGGCATTTGGGATAAGTAAGGAAGATATTTTCGGCATTTATACAGAAGGAGTTATTACGACGCATATTGGATTGGAGACATTCAAAACTCTGAGGAATCCGGGACTCCCGGGACGCAATTATATGGTGTCCCCAAATGGCAATTTGGTAATTCAGAAAGAAATTTCAAAATCTCCACGCTCCAAACCGCGGCCATCCGTATAATATT

Gene Information

NCBI Accession QBP05521.1
Location 148-504
Gene Name AV2
Protein Name pre-coat
Coding Region ATGTGGGATCCATTGTTAAACGAGTTTCCCGAAACCGTTCACGGTTTTAGATGTATGTTAGCAGTTAAATATTTGCAGTTAGTAGAAAAGACTTATTCTCCCGATACATTAGGTTACGATTTAATTAGGGATTTAATTTCAGTTATTAGGGCTAGGAACTATGGCGAAGCGACCAGCAGATATCATCATTTCAACGCCCGCATCGAAGGTACGTCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTCCGGGATGTACAGAAGTCCAGATGTCCCTAG
Protein Sequence MWDPLLNEFPETVHGFRCMLAVKYLQLVEKTYSPDTLGYDLIRDLISVIRARNYGEATSRYHHFNARIEGTSPSQLRQPICEPCCCPHCPRHQSKSMGEQAHEQKAQDVRDVQKSRCP

NCBI Accession QBP05522.1
Location 308-1078
Gene Name AV1
Protein Name coat protein
Coding Region ATGGCGAAGCGACCAGCAGATATCATCATTTCAACGCCCGCATCGAAGGTACGTCGCCGTCTCAACTTCGACAGCCCATATGTGAGCCGTGCTGCTGCCCCCATTGTCCGCGTCACCAAAGCAAAAGCATGGGCGAACAGGCCCATGAACAGAAAGCCCAGGATGTCCGGGATGTACAGAAGTCCAGATGTCCCTAGGGGCTGGGAAGGTCCAGTTAAGGTCCAGTCCTTTGGATGCAGACATGATTTTGATCACATGGGTAAGGCCATTTGTCTTTGTGATGTTACTAGGGGTATTGGGCTGACCCATCGAGTAGCGAAGAGGTTTTGTGTGAAGTCTGTTTATGTGTTGGGTAAAATATGGATGGATGAAAATATAAAGACCAAGAATCACACGAACAATGTGATGTTCTTTCTCGTTCGTGACCGTAGACCAGTTGACAAGCCTCAGGATTTTGGTGAGGTTTTTAACATGTTTGATAATGAGCCCAGCACGGTGACGGTGAAAAATGTGCATCGGGATAGGTACCAGGTGCTCAGGAAGTGGCATGCAACTGTGACAGGGGGTCAATATGCATCGAAGGAGCAGGCTCTCGTGAAGAAGTTTATTAGGGTTAATAATTATGTTGTGTACAACCAACAAGAGGCTGGCAAATATGAGAATCATACTGAGAATGCGTTAATGTTGTATATGGCGTGTACGCACGCCTCTAATCCCGTGTATGCTACATTGAAGATACGGATCTACTTCTATGACTCTGTATCGAATTAA
Protein Sequence MAKRPADIIISTPASKVRRRLNFDSPYVSRAAAPIVRVTKAKAWANRPMNRKPRMSGMYRSPDVPRGWEGPVKVQSFGCRHDFDHMGKAICLCDVTRGIGLTHRVAKRFCVKSVYVLGKIWMDENIKTKNHTNNVMFFLVRDRRPVDKPQDFGEVFNMFDNEPSTVTVKNVHRDRYQVLRKWHATVTGGQYASKEQALVKKFIRVNNYVVYNQQEAGKYENHTENALMLYMACTHASNPVYATLKIRIYFYDSVSN

NCBI Accession QBP05527.1
Location 338-973
Gene Name AC5
Protein Name AC5
Coding Region ATGATTCTCATATTTGCCAGCCTCTTGTTGGTTGTACACAACATAATTATTAACCCTAATAAACTTCTTCACGAGAGCCTGCTCCTTCGATGCATATTGACCCCCTGTCACAGTTGCATGCCACTTCCTGAGCACCTGGTACCTATCCCGATGCACATTTTTCACCGTCACCGTGCTGGGCTCATTATCAAACATGTTAAAAACCTCACCAAAATCCTGAGGCTTGTCAACTGGTCTACGGTCACGAACGAGAAAGAACATCACATTGTTCGTGTGATTCTTGGTCTTTATATTTTCATCCATCCATATTTTACCCAACACATAAACAGACTTCACACAAAACCTCTTCGCTACTCGATGGGTCAGCCCAATACCCCTAGTAACATCACAAAGACAAATGGCCTTACCCATGTGATCAAAATCATGTCTGCATCCAAAGGACTGGACCTTAACTGGACCTTCCCAGCCCCTAGGGACATCTGGACTTCTGTACATCCCGGACATCCTGGGCTTTCTGTTCATGGGCCTGTTCGCCCATGCTTTTGCTTTGGTGACGCGGACAATGGGGGCAGCAGCACGGCTCACATATGGGCTGTCGAAGTTGAGACGGCGACGTACCTTCGATGCGGGCGTTGA
Protein Sequence MILIFASLLLVVHNIIINPNKLLHESLLLRCILTPCHSCMPLPEHLVPIPMHIFHRHRAGLIIKHVKNLTKILRLVNWSTVTNEKEHHIVRVILGLYIFIHPYFTQHINRLHTKPLRYSMGQPNTPSNITKTNGLTHVIKIMSASKGLDLNWTFPAPRDIWTSVHPGHPGLSVHGPVRPCFCFGDADNGGSSTAHIWAVEVETATYLRCGR

NCBI Accession QBP05525.1
Location 1075-1479
Gene Name AC3
Protein Name replication enhancer protein
Coding Region ATGGATTCACGCACAGGGGAACTCATCACTGCAGCTCAGGAAATGAATGGGGTGTATATCTGGAAGGTCCCAAATCCCCTATATTTCAAGTCCTCAGACCACGACCAAAGGCCATTTTCCATGAACCACGACATCATCACTCTCCAGATCCAGTTCAATCACAACCTCAGGAAGGAACTGAGGATACTGAAGTGTTTTTTGGGCTTAAGAATCTGCATGGCTTTACAACCTCAGACCGGGCATTTCTTAAGAGTCTTTAGGAGTCAGGTTTTAAAGTATTTAGATAATCTAGGAGTCATTAGTATAAATAATGTAGTTAGGGCCTTTAAACATGTATTATACGATGTATCAGAACATGATGTATATTTAGACCAATCATCTTCAATAAAATTCTATATTTATTAA
Protein Sequence MDSRTGELITAAQEMNGVYIWKVPNPLYFKSSDHDQRPFSMNHDIITLQIQFNHNLRKELRILKCFLGLRICMALQPQTGHFLRVFRSQVLKYLDNLGVISINNVVRAFKHVLYDVSEHDVYLDQSSSIKFYIY

NCBI Accession QBP05524.1
Location 1220-1624
Gene Name AC2
Protein Name transcriptional activator protein
Coding Region ATGCAAAATTCATCACCCTCACAGAGCCACTGTACTCAGGTACCAATCAAGGTCCAACACAGGCTAGCCAAGCAGGGGACCATCCGGCGAAGTGTTGATCTCGAGGGTGGTTGCTCTTACTACGTACCATCAGCCTGCCACAATCATGGATTCACGCACAGGGGAACTCATCACTGCAGCTCAGGAAATGAATGGGGTGTATATCTGGAAGGTCCCAAATCCCCTATATTTCAAGTCCTCAGACCACGACCAAAGGCCATTTTCCATGAACCACGACATCATCACTCTCCAGATCCAGTTCAATCACAACCTCAGGAAGGAACTGAGGATACTGAAGTGTTTTTTGGGCTTAAGAATCTGCATGGCTTTACAACCTCAGACCGGGCATTTCTTAAGAGTCTTTAG
Protein Sequence MQNSSPSQSHCTQVPIKVQHRLAKQGTIRRSVDLEGGCSYYVPSACHNHGFTHRGTHHCSSGNEWGVYLEGPKSPIFQVLRPRPKAIFHEPRHHHSPDPVQSQPQEGTEDTEVFFGLKNLHGFTTSDRAFLKSL

NCBI Accession QBP05523.1
Location 1527-2612
Gene Name AC1
Protein Name replication associated protein
Coding Region ATGCGTCGTAATAACTCCTTCTGTATAAATGCCGAAAATATCTTCCTTACTTATCCCAAATGCCCAATACGCAAAGAGCAAATGCTCGAACTATTTAAAAACATTACCTGTCCTCTTGATAAATTGTTTATCAGAGTATCAAAAGAAAAACACCAAGATTGGTCTCTGCGTATCCAGGGTTTCATCCAATTCAAAGGGAAATTGCGGTTCAGAGAAGACAGACATTTTGAAATCGCTCGCCCTAATACCTCAAGCCAGTTCCACCCCGGGTTTCAGGGAGCTAAGTGCAGGTCAGGTGTCAAGTCCTACATCCAGAAGGGCGGAGAGTACATCGACTGGGGTGAGTTTCAGATCGGTGGGCGATTTGCTAGTGGAGGTCAACAGACAGGTAGTGATGGTGCAGCGGAGGCCCTAAATGCAGGTTCAGCGGAAGCTGCTTTAGCAATTATTAGGGAGAAACTCCCGGAAGATTTTATTTTTCAATATCATAATTTAAAAAATAATTTAGATAGGATTTGGACACCTCCAGTGGAGGTTTATGTTTCCCCCATTTCTTGTTGTTCATTCGATCAGGTGCCGGAGGCCATAGAGGAATGGGCTGCTGAAAATGTGATGGGTACCGCTGCGCGGCCATTGAGATCTAAAAGTATTGTCTTAGAGGGTGATAGTAGAACGGGGAAGACGATGTGGGCCAGGTCACTGGGTCCACACAATTATCTGTGTGGTCATTTAGACCTTAGTCCAAAGGTCTACAGCAACGAGGCCTGGTACAACGTCATTGATGACGTCGATCCCCACTACCTAGAGCACTTTAAAGAATTCATGGGGGCCCAAAGAGACTGGCAAAGCAACACCAAGTACGGGAAGCCCGTTCAAATTAAAGGGGGCATTCCCACTATCTTCCTCTGCAATCCTGGGTCCACTTCCAGCTATAAAGAGTTCTTGGACGAGGACAAGAATTCGGCACTAAGAGCGTGGGCTATAAAGAATGCAAAATTCATCACCCTCACAGAGCCACTGTACTCAGGTACCAATCAAGGTCCAACACAGGCTAGCCAAGCAGGGGACCATCCGGCGAAGTGTTGA
Protein Sequence MRRNNSFCINAENIFLTYPKCPIRKEQMLELFKNITCPLDKLFIRVSKEKHQDWSLRIQGFIQFKGKLRFREDRHFEIARPNTSSQFHPGFQGAKCRSGVKSYIQKGGEYIDWGEFQIGGRFASGGQQTGSDGAAEALNAGSAEAALAIIREKLPEDFIFQYHNLKNNLDRIWTPPVEVYVSPISCCSFDQVPEAIEEWAAENVMGTAARPLRSKSIVLEGDSRTGKTMWARSLGPHNYLCGHLDLSPKVYSNEAWYNVIDDVDPHYLEHFKEFMGAQRDWQSNTKYGKPVQIKGGIPTIFLCNPGSTSSYKEFLDEDKNSALRAWAIKNAKFITLTEPLYSGTNQGPTQASQAGDHPAKC

NCBI Accession QBP05526.1
Location 2198-2584
Gene Name AC4
Protein Name AC4 protein
Coding Region ATGCCGAAAATATCTTCCTTACTTATCCCAAATGCCCAATACGCAAAGAGCAAATGCTCGAACTATTTAAAAACATTACCTGTCCTCTTGATAAATTGTTTATCAGAGTATCAAAAGAAAAACACCAAGATTGGTCTCTGCGTATCCAGGGTTTCATCCAATTCAAAGGGAAATTGCGGTTCAGAGAAGACAGACATTTTGAAATCGCTCGCCCTAATACCTCAAGCCAGTTCCACCCCGGGTTTCAGGGAGCTAAGTGCAGGTCAGGTGTCAAGTCCTACATCCAGAAGGGCGGAGAGTACATCGACTGGGGTGAGTTTCAGATCGGTGGGCGATTTGCTAGTGGAGGTCAACAGACAGGTAGTGATGGTGCAGCGGAGGCCCTAA
Protein Sequence MPKISSLLIPNAQYAKSKCSNYLKTLPVLLINCLSEYQKKNTKIGLCVSRVSSNSKGNCGSEKTDILKSLALIPQASSTPGFRELSAGQVSSPTSRRAESTSTGVSFRSVGDLLVEVNRQVVMVQRRP

References More References in PubMed

1

Identification of Cotton leaf curl Gezira virus in Papaya in Oman.

Khan AJ, et al.  Plant Dis. 2012 Nov;96(11):1704. doi: 10.1094/PDIS-05-12-0438-PDN.

PMID: 30727467
2

Squash Yellow Leaf Curl Virus: A New Whitefly-Transmitted Poty-Like Virus.

Zouba AA, et al.  Plant Dis. 1998 May;82(5):475-478. doi: 10.1094/PDIS.1998.82.5.475.

PMID: 30856974
3

In silico identification of papaya genome-encoded microRNAs to target begomovirus genes in papaya leaf curl disease.

Srivastava A, et al.  Front Microbiol. 2024 Mar 21;15:1340275. doi: 10.3389/fmicb.2024.1340275. eCollection 2024.

PMID: 38605706
4

Leaf Curl Disease of Carica papaya from India May Be Caused by a Bipartite Geminivirus.

Saxena S, et al.  Plant Dis. 1998 Jan;82(1):126. doi: 10.1094/PDIS.1998.82.1.126A.

PMID: 30857046
5

A Mixed Infection of Lettuce chlorosis virus, Papaya ringspot virus, and Tomato yellow leaf curl virus-IL Detected in a Texas Papaya Orchard Affected by a Virus-Like Disease Outbreak.

Alabi OJ, et al.  Plant Dis. 2017 Jul;101(7):1094-1102. doi: 10.1094/PDIS-01-17-0118-RE. Epub 2017 Apr 19.

PMID: 30682949
6

First Report of Tomato leaf curl Palampur virus on Bitter Gourd in Pakistan.

Ali I, et al.  Plant Dis. 2010 Feb;94(2):276. doi: 10.1094/PDIS-94-2-0276A.

PMID: 30754274
7

First Report of Tomato leaf curl Albatinah virus (ToLCABV) and its Associated Betasatellite Infecting Papaya in Oman.

Ammara UE, et al.  Plant Dis. 2015 Mar;99(3):421. doi: 10.1094/PDIS-09-14-0912-PDN.

PMID: 30699712
8

Beneficial fungal root endophyte Piriformospora indica inhibits bitter gourd mosaic complex disease incited by combined infection of tomato leaf curl, papaya ringspot, and cucumber mosaic viruses without compromising crop growth and yield by orchestrating ROS production and scavenging through retrograde signaling.

Chandran DR, et al.  Front Microbiol. 2026 Mar 18;17:1781341. doi: 10.3389/fmicb.2026.1781341. eCollection 2026.

PMID: 41929680
9

Molecular characterization and infectivity of Papaya leaf curl China virus infecting tomato in China.

Zhang H, et al.  J Zhejiang Univ Sci B. 2010 Feb;11(2):109-14. doi: 10.1631/jzus.B0900176.

PMID: 20104645
10

Identification of an emerging cucumber virus in Taiwan using Oxford nanopore sequencing technology.

Dong ZX, et al.  Plant Methods. 2022 Dec 22;18(1):143. doi: 10.1186/s13007-022-00976-x.

PMID: 36550551