Hollyhock leaf curl virus
Basic Information
| Genus | Begomovirus |
|---|---|
| NCBI Assembly | GCF_002986605.1 |
| Isolate | Pakistan:Faisalabad |
| Release date | 2018/8/26 |
| Submitter | Zia Ur Rehman,M., Haider,M.S., Zia ur Rehman,M. |
| Host | |
| Download | Genome |GFF3 |PEP |CDS |
Genomic Organization
JBrowse
Genome
NC_038884
ACCGGATGGCCGCGCAATTTTTTTGGGTCCCACCACTAACTCTTGTCTGCCAATCATATACGGCGCTCAAAGCTTAAATAAATATCCCGCTTATTATAAATACTTCCTTGCTAAGTTTCAGTTTGAAAAATGTGGGATCCACTTTTAAACGAGTTCCCCGAGACGGTTCACGGGTTTCGTTGCATGCTTGCGATAAAATACCTGCAACTGCTGTCTGAGGAATACTCTCCGGATACGGTAGGTTACGATTTAATTCGCGATTTAATTTCTATTTTACGATCTAGGAATTATGTCGAAGCGTCCTGCCGATATCGTCATTTCTACCCCCGCGTCGAAGGTGCGTCGGCGTCTGAACTTCGACAGCCCCTATGCAACCCGTGCAGTTGTCCCCACTGTCCGCGTCACAAAATCACGCATGTGGGCGAACAGGCCCATGAACCGGAAGCCCAGAATGTACAGAATGTACAGAAGCCCTGATGTTCCAAGAGGCTGTGAGGGTCCATGTAAGGTCCAATCCTTTGAGTCCAGACACGATGTAGTCCATATAGGTAAGGTCATGTGTATTAGTGATGTTACTCGCGGTACTGGGCTGACCCATAGAGTTGGGAAACGTTTCTGTGTTAAATCAGTCTATGTATTGGGTAAGATCTGGATGGATGAAAACATAAAGTCCAAAAACCACACTAACAATGTGATGTTCTTCTTGGTCCGTGATCGACGGCCTGTGGATAAGCCTCAGGATTTTGGAGAGGTCTTCAACATGTTCGACAACGAGCCCAGCACCGCTACTGTCAAGAATGTTCATCGAGATCGCTACCAGGTGTTGAGGAAATGGTATGCAACAGTTACGGGTGGTCAATATGGAGCAAAGGAACAGGCCTTGGTCAAGAAGTTTGTCCGAGTTAACAATTATGTTGTTTACAATCAGCAAGAGGCAGGGAAATATGAGAATCATTCTGAGAATGCCCTGATGTTGTATATGGCATGTACCCATGCCTCTAATCCAGTTTACGCTACTCTTAAGATTAGGATTTACTTCTACGATTCTGTAACCAACTGATATTAATAAATATCGAATTTTATTTCTGAATTCATGTCTACGTACACAGTTTGTTCTATTTTTTCCCATAATACATGGTTTACAGCTCTGATAATTGAATTAATTGAGATTACACCCAGATTGTTGAGATACTTGAGGATTTGTGTCTTGAATACCCTTAAGAAAAGACCAGTCGGAGGGCGTAAGGTCGTCCAGATTCGGTAGGTCAGAAAACCACTTGTGACTCCCAGAGCTCTCCGAAGGTTGTAGTTGAATTGGATTCTGATCTTTATTATGTCCGTTGTCATTGTGAATGGCCGGTTGTCGTGGCTGAGGATCTTGAAATAGAGGGGATTTGGAACCTCCCAGGTATAGGCGCCACTCCATGCTTGAGCTGCAGTGATGGGTTCCCCTGTGCGTGAATCCATGGTTGAAGCAGTTTATAGATAGAAAATAAGAACACCCGCATTCAAGATCGACTCTCCTCCTCCTGTGTACCCTCTTGGCTTCCCTGTGCTGTACTTTGATTGGAACCGGAGTACAGTGGTCCTTCGAGGGTGACGAAAATCGCATTTTTGAGAGCCCAATTCTTTAATGCTGTGTTCTTGTCCTCGTCGAGGAATTCTTTATAGCTGCTGTTAGGACCAGGATTGCATAAGAAGATTGTCGGTATGCCGCCTTTAATTTGAACTGGCTTCCCGTACTTAGTGTTGGACTGCCAGTCCCTTTGGGCCCCCATAAACTCCTTAAAGTGCTTGAGGAAGTGCGGGTCGACGTCATCAATGACGTTGTACCACGCGTCGTTACTATAGACTTTTGGGCTTAGATCCAAATGCCCACATAAATAGTTATGTGGGCCTAGAGACCTAGCCCACATTGTTTTCCCAGTACGACTATCTCCCTCAATTACTATACTTTGAGGTCTCAGGGGCCGCGCAGCGGCGTCGACAACATTCTCAGACACCCACTCTTCAAGTTCTTCTGGAACTTGATCGAAAGAAGAATAGGAAAAAGGAGAAACATAAGGAGCTGGAGGCTCCTGAAAGATCCTGTCTAGATTTGCATTTAAATTATGAAATTGTAGTACAAAATCTTTAGGAGCTAGTTCCTTAATGACTCTAAGAGCCTCTGACTTACTTCCCGCGTTAAGTGCTGCGGCGTAAGCGTCGTTGGCTGTTTGTTGCCCTCCTCTTGCTGATCTTCCGTCGATCTGAAATTCGCCCCAGTCGAGAATGTCCCCGTCCTTAGCGATGTAGGACTTGACGTCGGAGCTGGATTTAGCTCCCTGAATGTTTGGATGGAAATGTGCTGACCTGGTTGGGGATACGAGGTCGAAGAATCTGTTATTTTTGCATTTGTATTTGCCCTCGAACTGGATGAGCACGTGAAGATGAGGTTCCCCATTTTCATGAAACTCTCTGCAGATTCTAATGTATTTTTTGTTTACTGGTGTCTGTAGGTTTTGTAATTGGGAAAGTGCTTCCTCTTTAGTAAGAGAGCAAGTGGGATAAGTGAGGAAATAATTTTTGGCATATATCTGAAATTGTTTGGGAGGAGCCATTGACTTGGTCAATCGGTACCCAGATATAGTCTTATGTCAATTGGTGAACGGTACCCTATATATATTGGGTACTGAATGGCAATATTTGTAATTATGAAAATAAATTCAAAATCCTCACGCTCCAAAAAGCGGCCATCCGTATAATATT
Gene Information
| NCBI Accession | YP_009508128.1 |
|---|---|
| Location | 130-477 |
| Gene Name | av2 |
| Protein Name | pre-coat protein |
| Coding Region | ATGTGGGATCCACTTTTAAACGAGTTCCCCGAGACGGTTCACGGGTTTCGTTGCATGCTTGCGATAAAATACCTGCAACTGCTGTCTGAGGAATACTCTCCGGATACGGTAGGTTACGATTTAATTCGCGATTTAATTTCTATTTTACGATCTAGGAATTATGTCGAAGCGTCCTGCCGATATCGTCATTTCTACCCCCGCGTCGAAGGTGCGTCGGCGTCTGAACTTCGACAGCCCCTATGCAACCCGTGCAGTTGTCCCCACTGTCCGCGTCACAAAATCACGCATGTGGGCGAACAGGCCCATGAACCGGAAGCCCAGAATGTACAGAATGTACAGAAGCCCTGA |
| Protein Sequence | MWDPLLNEFPETVHGFRCMLAIKYLQLLSEEYSPDTVGYDLIRDLISILRSRNYVEASCRYRHFYPRVEGASASELRQPLCNPCSCPHCPRHKITHVGEQAHEPEAQNVQNVQKP |
| NCBI Accession | YP_009508129.1 |
|---|---|
| Location | 290-1060 |
| Gene Name | av1 |
| Protein Name | coat protein |
| Coding Region | ATGTCGAAGCGTCCTGCCGATATCGTCATTTCTACCCCCGCGTCGAAGGTGCGTCGGCGTCTGAACTTCGACAGCCCCTATGCAACCCGTGCAGTTGTCCCCACTGTCCGCGTCACAAAATCACGCATGTGGGCGAACAGGCCCATGAACCGGAAGCCCAGAATGTACAGAATGTACAGAAGCCCTGATGTTCCAAGAGGCTGTGAGGGTCCATGTAAGGTCCAATCCTTTGAGTCCAGACACGATGTAGTCCATATAGGTAAGGTCATGTGTATTAGTGATGTTACTCGCGGTACTGGGCTGACCCATAGAGTTGGGAAACGTTTCTGTGTTAAATCAGTCTATGTATTGGGTAAGATCTGGATGGATGAAAACATAAAGTCCAAAAACCACACTAACAATGTGATGTTCTTCTTGGTCCGTGATCGACGGCCTGTGGATAAGCCTCAGGATTTTGGAGAGGTCTTCAACATGTTCGACAACGAGCCCAGCACCGCTACTGTCAAGAATGTTCATCGAGATCGCTACCAGGTGTTGAGGAAATGGTATGCAACAGTTACGGGTGGTCAATATGGAGCAAAGGAACAGGCCTTGGTCAAGAAGTTTGTCCGAGTTAACAATTATGTTGTTTACAATCAGCAAGAGGCAGGGAAATATGAGAATCATTCTGAGAATGCCCTGATGTTGTATATGGCATGTACCCATGCCTCTAATCCAGTTTACGCTACTCTTAAGATTAGGATTTACTTCTACGATTCTGTAACCAACTGA |
| Protein Sequence | MSKRPADIVISTPASKVRRRLNFDSPYATRAVVPTVRVTKSRMWANRPMNRKPRMYRMYRSPDVPRGCEGPCKVQSFESRHDVVHIGKVMCISDVTRGTGLTHRVGKRFCVKSVYVLGKIWMDENIKSKNHTNNVMFFLVRDRRPVDKPQDFGEVFNMFDNEPSTATVKNVHRDRYQVLRKWYATVTGGQYGAKEQALVKKFVRVNNYVVYNQQEAGKYENHSENALMLYMACTHASNPVYATLKIRIYFYDSVTN |
| NCBI Accession | YP_009508130.1 |
|---|---|
| Location | 1063-1467 |
| Gene Name | ac3 |
| Protein Name | replication enhancer protein |
| Coding Region | ATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCATGGAGTGGCGCCTATACCTGGGAGGTTCCAAATCCCCTCTATTTCAAGATCCTCAGCCACGACAACCGGCCATTCACAATGACAACGGACATAATAAAGATCAGAATCCAATTCAACTACAACCTTCGGAGAGCTCTGGGAGTCACAAGTGGTTTTCTGACCTACCGAATCTGGACGACCTTACGCCCTCCGACTGGTCTTTTCTTAAGGGTATTCAAGACACAAATCCTCAAGTATCTCAACAATCTGGGTGTAATCTCAATTAATTCAATTATCAGAGCTGTAAACCATGTATTATGGGAAAAAATAGAACAAACTGTGTACGTAGACATGAATTCAGAAATAAAATTCGATATTTATTAA |
| Protein Sequence | MDSRTGEPITAAQAWSGAYTWEVPNPLYFKILSHDNRPFTMTTDIIKIRIQFNYNLRRALGVTSGFLTYRIWTTLRPPTGLFLRVFKTQILKYLNNLGVISINSIIRAVNHVLWEKIEQTVYVDMNSEIKFDIY |
| NCBI Accession | YP_009508131.1 |
|---|---|
| Location | 1160-1612 |
| Gene Name | ac2 |
| Protein Name | transcriptional activator protein |
| Coding Region | ATGCGATTTTCGTCACCCTCGAAGGACCACTGTACTCCGGTTCCAATCAAAGTACAGCACAGGGAAGCCAAGAGGGTACACAGGAGGAGGAGAGTCGATCTTGAATGCGGGTGTTCTTATTTTCTATCTATAAACTGCTTCAACCATGGATTCACGCACAGGGGAACCCATCACTGCAGCTCAAGCATGGAGTGGCGCCTATACCTGGGAGGTTCCAAATCCCCTCTATTTCAAGATCCTCAGCCACGACAACCGGCCATTCACAATGACAACGGACATAATAAAGATCAGAATCCAATTCAACTACAACCTTCGGAGAGCTCTGGGAGTCACAAGTGGTTTTCTGACCTACCGAATCTGGACGACCTTACGCCCTCCGACTGGTCTTTTCTTAAGGGTATTCAAGACACAAATCCTCAAGTATCTCAACAATCTGGGTGTAATCTCAATTAA |
| Protein Sequence | MRFSSPSKDHCTPVPIKVQHREAKRVHRRRRVDLECGCSYFLSINCFNHGFTHRGTHHCSSSMEWRLYLGGSKSPLFQDPQPRQPAIHNDNGHNKDQNPIQLQPSESSGSHKWFSDLPNLDDLTPSDWSFLKGIQDTNPQVSQQSGCNLN |
| NCBI Accession | YP_009508132.1 |
|---|---|
| Location | 1509-2600 |
| Gene Name | ac1 |
| Protein Name | replication associated protein |
| Coding Region | ATGGCTCCTCCCAAACAATTTCAGATATATGCCAAAAATTATTTCCTCACTTATCCCACTTGCTCTCTTACTAAAGAGGAAGCACTTTCCCAATTACAAAACCTACAGACACCAGTAAACAAAAAATACATTAGAATCTGCAGAGAGTTTCATGAAAATGGGGAACCTCATCTTCACGTGCTCATCCAGTTCGAGGGCAAATACAAATGCAAAAATAACAGATTCTTCGACCTCGTATCCCCAACCAGGTCAGCACATTTCCATCCAAACATTCAGGGAGCTAAATCCAGCTCCGACGTCAAGTCCTACATCGCTAAGGACGGGGACATTCTCGACTGGGGCGAATTTCAGATCGACGGAAGATCAGCAAGAGGAGGGCAACAAACAGCCAACGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCAGAGGCTCTTAGAGTCATTAAGGAACTAGCTCCTAAAGATTTTGTACTACAATTTCATAATTTAAATGCAAATCTAGACAGGATCTTTCAGGAGCCTCCAGCTCCTTATGTTTCTCCTTTTTCCTATTCTTCTTTCGATCAAGTTCCAGAAGAACTTGAAGAGTGGGTGTCTGAGAATGTTGTCGACGCCGCTGCGCGGCCCCTGAGACCTCAAAGTATAGTAATTGAGGGAGATAGTCGTACTGGGAAAACAATGTGGGCTAGGTCTCTAGGCCCACATAACTATTTATGTGGGCATTTGGATCTAAGCCCAAAAGTCTATAGTAACGACGCGTGGTACAACGTCATTGATGACGTCGACCCGCACTTCCTCAAGCACTTTAAGGAGTTTATGGGGGCCCAAAGGGACTGGCAGTCCAACACTAAGTACGGGAAGCCAGTTCAAATTAAAGGCGGCATACCGACAATCTTCTTATGCAATCCTGGTCCTAACAGCAGCTATAAAGAATTCCTCGACGAGGACAAGAACACAGCATTAAAGAATTGGGCTCTCAAAAATGCGATTTTCGTCACCCTCGAAGGACCACTGTACTCCGGTTCCAATCAAAGTACAGCACAGGGAAGCCAAGAGGGTACACAGGAGGAGGAGAGTCGATCTTGA |
| Protein Sequence | MAPPKQFQIYAKNYFLTYPTCSLTKEEALSQLQNLQTPVNKKYIRICREFHENGEPHLHVLIQFEGKYKCKNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIAKDGDILDWGEFQIDGRSARGGQQTANDAYAAALNAGSKSEALRVIKELAPKDFVLQFHNLNANLDRIFQEPPAPYVSPFSYSSFDQVPEELEEWVSENVVDAAARPLRPQSIVIEGDSRTGKTMWARSLGPHNYLCGHLDLSPKVYSNDAWYNVIDDVDPHFLKHFKEFMGAQRDWQSNTKYGKPVQIKGGIPTIFLCNPGPNSSYKEFLDEDKNTALKNWALKNAIFVTLEGPLYSGSNQSTAQGSQEGTQEEESRS |
| NCBI Accession | YP_009508133.1 |
|---|---|
| Location | 2141-2449 |
| Gene Name | ac4 |
| Protein Name | AC4 protein |
| Coding Region | ATGAAAATGGGGAACCTCATCTTCACGTGCTCATCCAGTTCGAGGGCAAATACAAATGCAAAAATAACAGATTCTTCGACCTCGTATCCCCAACCAGGTCAGCACATTTCCATCCAAACATTCAGGGAGCTAAATCCAGCTCCGACGTCAAGTCCTACATCGCTAAGGACGGGGACATTCTCGACTGGGGCGAATTTCAGATCGACGGAAGATCAGCAAGAGGAGGGCAACAAACAGCCAACGACGCTTACGCCGCAGCACTTAACGCGGGAAGTAAGTCAGAGGCTCTTAGAGTCATTAAGGAACTAG |
| Protein Sequence | MKMGNLIFTCSSSSRANTNAKITDSSTSYPQPGQHISIQTFRELNPAPTSSPTSLRTGTFSTGANFRSTEDQQEEGNKQPTTLTPQHLTREVSQRLLESLRN |
References More References in PubMed
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| 3 |
Khan A, et al. Arch Virol. 2021 Sep;166(9):2607-2610. doi: 10.1007/s00705-021-05134-7. Epub 2021 Jun 11. PMID: 34115211 |
| 4 |
Cotton leaf curl virus disease. Briddon RW, et al. Virus Res. 2000 Nov;71(1-2):151-9. doi: 10.1016/s0168-1702(00)00195-7. PMID: 11137169 |
| 5 |
Mahmood MA, et al. Sci Rep. 2024 Jun 12;14(1):13532. doi: 10.1038/s41598-024-63211-8. PMID: 38866855 |
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Cotton Leaf Curl Disease: Which Whitefly Is the Vector? Pan LL, et al. Phytopathology. 2018 Oct;108(10):1172-1183. doi: 10.1094/PHYTO-01-18-0015-R. Epub 2018 Aug 21. PMID: 29714092 |
| 7 |
Identification of Cotton leaf curl Gezira virus in Papaya in Oman. Khan AJ, et al. Plant Dis. 2012 Nov;96(11):1704. doi: 10.1094/PDIS-05-12-0438-PDN. PMID: 30727467 |
| 8 |
Infectivity of okra enation leaf curl virus and the role of its V2 protein in pathogenicity. Saeed F, et al. Virus Res. 2018 Aug 15;255:90-94. doi: 10.1016/j.virusres.2018.07.007. Epub 2018 Jul 18. PMID: 30009848 |
| 9 |
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| 10 |
Using Multiplexed CRISPR/Cas9 for Suppression of Cotton Leaf Curl Virus. Binyameen B, et al. Int J Mol Sci. 2021 Nov 21;22(22):12543. doi: 10.3390/ijms222212543. PMID: 34830426 |